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30 relations: Acute proliferative glomerulonephritis, Acylation stimulating protein, Alternative complement pathway, Anaphylatoxin, B cell, Blood, C3-convertase, C3a (complement), C3b, Chromosome 19, Cofactor (biochemistry), Complement factor B, Complement factor I, Complement system, Decay-accelerating factor, Factor H, Gene, Hepatocyte, Immune system, Innate immune system, Keratinocyte, Lectin pathway, Membranoproliferative glomerulonephritis, Nucleophile, Opsonin, Protein, Protein–protein interaction, Proteolysis, Shunt nephritis, Thioester.
Acute proliferative glomerulonephritis
Acute proliferative glomerulonephritis is a disorder of the glomeruli (glomerulonephritis), or small blood vessels in the kidneys.
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Acylation stimulating protein
Complement 3 (C3) through its interaction with factors B and D (adipsin) generates C3a.
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Alternative complement pathway
The alternative pathway of the complement system is an innate component of the immune system's natural defense against infections.
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Anaphylatoxin
Anaphylatoxins, or complement peptides, are fragments (C3a, C4a and C5a) that are produced as part of the activation of the complement system.
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B cell
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.
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Blood
Blood is a body fluid in humans and other animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells.
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C3-convertase
C3 convertase (C2, C4bC2b, (formerly C4bC2a)C3bBb, complement C.hivin.4.hivin2, complement C3 convertase) belongs to family of serine proteases and is necessary in innate immunity as a part of the complement system which eventuate in opsonisation of particles, release of inflammatory peptides, C5 convertase formation and cell lysis.
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C3a (complement)
C3a is one of the proteins formed by the cleavage of complement component 3; the other is C3b.
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C3b
C3b is the larger of two elements formed by the cleavage of complement component 3, and is considered an important part of the innate immune system.
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Chromosome 19
Chromosome 19 is one of the 23 pairs of chromosomes in humans.
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Cofactor (biochemistry)
A cofactor is a non-protein chemical compound or metallic ion that is required for an enzyme's activity.
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Complement factor B
Complement factor B is a protein that in humans is encoded by the CFB gene.
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Complement factor I
Complement factor I, also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene.
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Complement system
The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's cell membrane.
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Decay-accelerating factor
Complement decay-accelerating factor, also known as CD55 or DAF, is a protein that, in humans, is encoded by the CD55 gene.
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Factor H
Factor H is a member of the regulators of complement activation family and is a complement control protein.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Hepatocyte
A hepatocyte is a cell of the main parenchymal tissue of the liver.
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Immune system
The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.
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Innate immune system
The innate immune system, also known as the non-specific immune system or in-born immunity system, is an important subsystem of the overall immune system that comprises the cells and mechanisms involved in the defense of the host from infection by other organisms.
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Keratinocyte
A keratinocyte is the predominant cell type in the epidermis, the outermost layer of the skin, constituting 90% of the cells found there.
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Lectin pathway
The lectin pathway is a type of cascade reaction in the complement system, similar in structure to the classical complement pathway, in that, after activation, it proceeds through the action of C4 and C2 to produce activated complement proteins further down the cascade.
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Membranoproliferative glomerulonephritis
Membranoproliferative glomerulonephritis ("MPGN"), also known as mesangiocapillary glomerulonephritis, is a type of glomerulonephritis caused by deposits in the kidney glomerular mesangium and basement membrane (GBM) thickening, activating complement and damaging the glomeruli.
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Nucleophile
Nucleophile is a chemical species that donates an electron pair to an electrophile to form a chemical bond in relation to a reaction.
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Opsonin
An opsonin (from the Greek opsōneîn, to prepare for eating) is any molecule that enhances phagocytosis by marking an antigen for an immune response or marking dead cells for recycling (i.e., causes the phagocyte to "relish" the marked cell).
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids.
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Shunt nephritis
Shunt nephritis is a rare disease of the kidney that can occur in patients being treated for hydrocephalus with a cerebral shunt.
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Thioester
In chemistry thioesters are compounds with the functional group R–S–CO–R'.
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Redirects here:
C3 (complement), C3 (gene), CPAMD1, Complement C3, Complement c3, Complement component 3b, Cpamd1.
References
[1] https://en.wikipedia.org/wiki/Complement_component_3
