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Cross-presentation

Index Cross-presentation

Cross-presentation is the ability of certain antigen-presenting cells to take up, process and present extracellular antigens with MHC class I molecules to CD8 T cells (cytotoxic T cells). [1]

42 relations: Adaptive immune system, Antigen processing, Antigen-presenting cell, Autoimmune disease, B cell, Bacteria, Beta-2 microglobulin, Calreticulin, Cancer immunotherapy, Cancer vaccine, Cauliflower mosaic virus, Central tolerance, Cytoplasm, Cytotoxic T cell, Cytotoxicity, Dendritic cell, Endocytosis, Endoplasmic reticulum, Epstein–Barr virus, ERAP, Herpesviridae, Immune tolerance, Interferon type I, Liver sinusoid, Macrophage, Medullary thymic epithelial cells, MHC class I, MHC class II, Minor histocompatibility antigen, Neoplasm, Orthomyxoviridae, Papillomaviridae, Peripheral tolerance, Plasmacytoid dendritic cell, Proteasome, Simian immunodeficiency virus, T helper cell, Tapasin, Thymus, Transporter associated with antigen processing, Vaccination, Virus.

Adaptive immune system

The adaptive immune system, also known as the acquired immune system or, more rarely, as the specific immune system, is a subsystem of the overall immune system that is composed of highly specialized, systemic cells and processes that eliminate pathogens or prevent their growth.

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Antigen processing

Antigen processing is an immunological process that prepares antigens for presentation to special cells of the immune system called T lymphocytes.

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Antigen-presenting cell

An antigen-presenting cell (APC) or accessory cell is a cell that displays antigen complexed with major histocompatibility complexes (MHCs) on their surfaces; this process is known as antigen presentation.

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Autoimmune disease

An autoimmune disease is a condition arising from an abnormal immune response to a normal body part.

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B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.

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Bacteria

Bacteria (common noun bacteria, singular bacterium) is a type of biological cell.

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Beta-2 microglobulin

β2 microglobulin also known as B2M is a component of MHC class I molecules, MHC class I molecules have α1, α2, and α3 proteins which are present on all nucleated cells (excludes red blood cells).

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Calreticulin

Calreticulin also known as calregulin, CRP55, CaBP3, calsequestrin-like protein, and endoplasmic reticulum resident protein 60 (ERp60) is a protein that in humans is encoded by the CALR gene.

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Cancer immunotherapy

Cancer immunotherapy (sometimes called immuno-oncology, abbreviated IO) is the use of the immune system to treat cancer.

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Cancer vaccine

A cancer vaccine is a vaccine that either treats existing cancer or prevents development of a cancer.

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Cauliflower mosaic virus

Cauliflower mosaic virus (CaMV) is a member of the genus Caulimovirus, one of the six genera in the Caulimoviridae family, which are pararetroviruses that infect plants.

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Central tolerance

Central tolerance, also known as negative selection, is the process of eliminating any developing T or B lymphocytes that are reactive to self.

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Cytoplasm

In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.

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Cytotoxic T cell

A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected (particularly with viruses), or cells that are damaged in other ways.

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Cytotoxicity

Cytotoxicity is the quality of being toxic to cells.

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Dendritic cell

Dendritic cells (DCs) are antigen-presenting cells (also known as accessory cells) of the mammalian immune system.

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Endocytosis

Endocytosis is a form of bulk transport in which a cell transports molecules (such as proteins) into the cell (endo- + cytosis) by engulfing them in an energy-using process.

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Endoplasmic reticulum

The endoplasmic reticulum (ER) is a type of organelle found in eukaryotic cells that forms an interconnected network of flattened, membrane-enclosed sacs or tube-like structures known as cisternae.

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Epstein–Barr virus

The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is one of eight known human herpesvirus types in the herpes family, and is one of the most common viruses in humans.

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ERAP

Entreprise de recherches et d'activités pétrolières is a French petroleum company created in 1965 by the merger of RAP (Régie autonome des pétroles) and BRP (Bureau de recherche des pétroles).

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Herpesviridae

Herpesviridae is a large family of DNA viruses that cause diseases in animals, including humans.

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Immune tolerance

Immune tolerance, or immunological tolerance, or immunotolerance, is a state of unresponsiveness of the immune system to substances or tissue that have the capacity to elicit an immune response in given organism.It is induced by prior exposure to that specific antigen.

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Interferon type I

Human type I interferons (IFNs) are a large subgroup of interferon proteins that help regulate the activity of the immune system.

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Liver sinusoid

A liver sinusoid is a type of sinusoidal blood vessel (with fenestrated, discontinuous endothelium) that serves as a location for mixing of the oxygen-rich blood from the hepatic artery and the nutrient-rich blood from the portal vein.

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Macrophage

Macrophages (big eaters, from Greek μακρός (makrós).

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Medullary thymic epithelial cells

Medullary thymic epithelial cells (mTECs) represent unique stromal cell population of the thymus which plays essential role in the establishment of central tolerance.

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MHC class I

MHC class I molecules are one of two primary classes of major histocompatibility complex (MHC) molecules (the other being MHC class II) and are found on the cell surface of all nucleated cells in the bodies of jawed vertebrates.

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MHC class II

MHC class II molecules are a class of major histocompatibility complex (MHC) molecules normally found only on antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells.

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Minor histocompatibility antigen

Minor histocompatibility antigen (also known as MiHA) are receptors on the cellular surface of donated organs that are known to give an immunological response in some organ transplants.

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Neoplasm

Neoplasia is a type of abnormal and excessive growth of tissue.

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Orthomyxoviridae

The Orthomyxoviruses (ὀρθός, orthós, Greek for "straight"; μύξα, mýxa, Greek for "mucus") are a family of RNA viruses that includes seven genera: Influenza virus A, Influenza virus B, Influenza virus C, Influenza virus D, Isavirus, Thogotovirus and Quaranjavirus.

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Papillomaviridae

Papillomaviridae is an ancient taxonomic family of non-enveloped DNA viruses, collectively known as papillomaviruses.

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Peripheral tolerance

Peripheral tolerance is the second branch of immunological tolerance, after central tolerance.

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Plasmacytoid dendritic cell

Plasmacytoid dendritic cells (pDCs) are a rare type of immune cell that are known to secrete large quantities of type 1 interferon (IFNs) in response to a viral infection.

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Proteasome

Proteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds.

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Simian immunodeficiency virus

Simian immunodeficiency viruses (SIVs) are retroviruses that cause persistent infections in at least 45 species of African non-human primates.

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T helper cell

The T helper cells (Th cells) are a type of T cell that play an important role in the immune system, particularly in the adaptive immune system.

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Tapasin

TAP-associated glycoprotein also known as tapasin or TAPBP is a protein that in humans is encoded by the TAPBP gene.

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Thymus

The thymus is a specialized primary lymphoid organ of the immune system.

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Transporter associated with antigen processing

Transporter associated with antigen processing (TAP) is a member of the ATP-binding-cassette transporter family.

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Vaccination

Vaccination is the administration of antigenic material (a vaccine) to stimulate an individual's immune system to develop adaptive immunity to a pathogen.

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Virus

A virus is a small infectious agent that replicates only inside the living cells of other organisms.

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Redirects here:

Cross presentation, Cross-priming, Crosspresentation.

References

[1] https://en.wikipedia.org/wiki/Cross-presentation

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