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16 relations: Antiestrogen, Breast cancer, Cell (biology), Clinical trial, Estradiol, Estrogen, Estrogen receptor, In vitro, Ligand (biochemistry), MCF-7, Metabolite, Methodology, Nonsteroidal, Selective estrogen receptor modulator, Zindoxifene, 2-Phenylindole.
Antiestrogen
Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body.
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Breast cancer
Breast cancer is cancer that develops from breast tissue.
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Cell (biology)
The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.
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Clinical trial
Clinical trials are experiments or observations done in clinical research.
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Estradiol
Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone.
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Estrogen
Estrogen, or oestrogen, is the primary female sex hormone.
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Estrogen receptor
Estrogen receptors (ERs) are a group of proteins found inside cells.
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In vitro
In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.
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Ligand (biochemistry)
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
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MCF-7
MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old Caucasian woman.
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Metabolite
A metabolite is the intermediate end product of metabolism.
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Methodology
Methodology is the systematic, theoretical analysis of the methods applied to a field of study.
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Nonsteroidal
Nonsteroidal is a term which is used to describe a compound that is not a steroid.
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Selective estrogen receptor modulator
Selective estrogen receptor modulators (SERMs) are a class of drugs that act on the estrogen receptor (ER).
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Zindoxifene
Zindoxifene (INN; former developmental code names D-16726, NSC-341952) is a nonsteroidal selective estrogen receptor modulator (SERM) that was under development in the 1980s and early 1990s for the treatment of breast cancer but was not marketed.
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2-Phenylindole
2-Phenylindole is an organic compound.
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