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Dimethandrolone undecanoate

Index Dimethandrolone undecanoate

Dimethandrolone undecanoate (DMAU), also known by its developmental code name CDB-4521, is an experimental androgen/anabolic steroid (AAS) and progestogen medication which is under development as a potential birth control pill for men. [1]

86 relations: Acne, Agonist, Anabolic steroid, Androgen, Androgen ester, Androgen receptor, Androgen replacement therapy, Androgen-dependent condition, Antigonadotropin, Aromatase, Benign prostatic hyperplasia, Benzyl benzoate, Biological target, Biosynthesis, Birth control, Bone density, Capsule (pharmacy), Castor oil, Combined oral contraceptive pill, Derivative (chemistry), Dimethandrolone, Dimethandrolone buciclate, Dimethandrolone dodecylcarbonate, Erectile dysfunction, Ester, Estrane, Estrogen, Estrogen (medication), Eunice Kennedy Shriver National Institute of Child Health and Human Development, Experimental drug, Federal government of the United States, Fertility, Hair follicle, Hepatotoxicity, High-density lipoprotein, Hormonal contraception, Hydrolysis, Hypertrichosis, Hypoactive sexual desire disorder, Hypoestrogenism, Hypogonadism, Intramuscular injection, Kidney, Liver, Luteinizing hormone, Male contraceptive, Methyl group, Methyltestosterone, Nandrolone, National Institutes of Health, ..., Oral administration, Orchiectomy, Organic compound, Osteoporosis, Patent, Pattern hair loss, Pharmacokinetics, Prodrug, Progesterone, Progesterone receptor, Progestin, Progestogen, Prostate, Prostate cancer, Self-microemulsifying drug delivery system, Sexual dysfunction, Side effect, Skin, Spermatogenesis, Steric effects, Steroid, Substrate (chemistry), Symptom, Testicle, Testosterone, Testosterone undecanoate, Tissue (biology), Tolerability, Trestolone, Trestolone acetate, Undecylic acid, United States Department of Health and Human Services, Weight gain, 11β-Methyl-19-nortestosterone dodecylcarbonate, 17α-Alkylated anabolic steroid, 5α-Reductase. Expand index (36 more) »

Acne

Acne, also known as acne vulgaris, is a long-term skin disease that occurs when hair follicles are clogged with dead skin cells and oil from the skin.

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Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Anabolic steroid

Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone.

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Androgen

An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.

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Androgen ester

An androgen or anabolic steroid ester is an ester of an androgen/anabolic steroid (AAS) such as the natural testosterone or dihydrotestosterone (DHT) or the synthetic nandrolone (19-nortestosterone).

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Androgen receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.

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Androgen replacement therapy

Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a class of hormone replacement therapy in which androgens, often testosterone, are replaced.

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Androgen-dependent condition

An androgen-dependent condition, disease, disorder, or syndrome, is a medical condition that is, in part or full, dependent on, or is sensitive to, the presence of androgenic activity in the body.

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Antigonadotropin

An antigonadotropin is a drug which suppresses the activity and/or downstream effects of one or both of the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH).

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Aromatase

Aromatase, also called estrogen synthetase or estrogen synthase, is an enzyme responsible for a key step in the biosynthesis of estrogens.

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Benign prostatic hyperplasia

Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate.

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Benzyl benzoate

Benzyl benzoate (BnBzO), sold under the brand name Scabanca among others, is a medication and insect repellent.

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Biological target

A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function.

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Biosynthesis

Biosynthesis (also called anabolism) is a multi-step, enzyme-catalyzed process where substrates are converted into more complex products in living organisms.

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Birth control

Birth control, also known as contraception and fertility control, is a method or device used to prevent pregnancy.

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Bone density

Bone density, or bone mineral density (BMD), is the amount of bone mineral in bone tissue.

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Capsule (pharmacy)

In the manufacture of pharmaceuticals, encapsulation refers to a range of dosage forms—techniques used to enclose medicines—in a relatively stable shell known as a capsule, allowing them to, for example, be taken orally or be used as suppositories.

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Castor oil

Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (Ricinus communis).

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Combined oral contraceptive pill

The combined oral contraceptive pill (COCP), often referred to as the birth control pill or colloquially as "the pill", is a type of birth control that is designed to be taken orally by women.

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Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

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Dimethandrolone

Dimethandrolone (DMA), also known by its developmental code name CDB-1321, is an experimental androgen/anabolic steroid (AAS) and progestogen medication which is under investigation for potential clinical use.

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Dimethandrolone buciclate

Dimethandrolone buciclate (developmental code name CDB-4386A), or dimethandrolone bucyclate, also known as 7α,11β-dimethyl-19-nortestosterone 17β-buciclate, is a synthetic anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was developed by the Contraceptive Development Branch (CDB) of the National Institute of Child Health and Human Development (NICHD) and has not been marketed at this time.

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Dimethandrolone dodecylcarbonate

Dimethandrolone dodecylcarbonate (developmental code name CDB-4730), or dimethandrolone dodecanoylcarbonate, also known as 7α,11β-dimethyl-19-nortestosterone 17β-dodecylcarbonate, is a synthetic and orally active anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was developed by the Contraceptive Development Branch (CDB) of the National Institute of Child Health and Human Development (NICHD) and has not been marketed at this time.

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Erectile dysfunction

Erectile dysfunction (ED), also known as impotence, is a type of sexual dysfunction characterized by the inability to develop or maintain an erection of the penis during sexual activity.

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Ester

In chemistry, an ester is a chemical compound derived from an acid (organic or inorganic) in which at least one –OH (hydroxyl) group is replaced by an –O–alkyl (alkoxy) group.

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Estrane

Estrane is a C18 steroid derivative, with a gonane core.

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Estrogen

Estrogen, or oestrogen, is the primary female sex hormone.

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Estrogen (medication)

An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.

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Eunice Kennedy Shriver National Institute of Child Health and Human Development

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is one of the National Institutes of Health (NIH) in the United States Department of Health and Human Services.

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Experimental drug

An experimental drug is a medicinal product (a drug or vaccine) that has not yet received approval from governmental regulatory authorities for routine use in human or veterinary medicine.

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Federal government of the United States

The federal government of the United States (U.S. federal government) is the national government of the United States, a constitutional republic in North America, composed of 50 states, one district, Washington, D.C. (the nation's capital), and several territories.

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Fertility

Fertility is the natural capability to produce offspring.

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Hair follicle

The hair follicle is a dynamic organ found in mammalian skin.

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Hepatotoxicity

Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage.

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High-density lipoprotein

High-density lipoproteins (HDL) are one of the five major groups of lipoproteins.

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Hormonal contraception

Hormonal contraception refers to birth control methods that act on the endocrine system.

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Hydrolysis

Hydrolysis is a term used for both an electro-chemical process and a biological one.

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Hypertrichosis

Hypertrichosis is an abnormal amount of hair growth over the body.

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Hypoactive sexual desire disorder

Hypoactive sexual desire disorder (HSDD) or inhibited sexual desire (ISD) is considered a sexual dysfunction and is characterized as a lack or absence of sexual fantasies and desire for sexual activity, as judged by a clinician.

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Hypoestrogenism

Hypoestrogenism, or estrogen deficiency, refers to a lower than normal level of estrogen, the primary sex hormone in women.

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Hypogonadism

Hypogonadism means diminished functional activity of the gonads—the testes or the ovaries —that may result in diminished sex hormone biosynthesis.

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Intramuscular injection

Intramuscular (also IM or im) injection is the injection of a substance directly into muscle.

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Kidney

The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.

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Liver

The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.

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Luteinizing hormone

Luteinizing hormone (LH, also known as lutropin and sometimes lutrophin) is a hormone produced by gonadotropic cells in the anterior pituitary gland.

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Male contraceptive

Male contraceptives, also known as male birth control are methods of preventing pregnancy that primarily involve the male physiology.

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Methyl group

A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3.

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Methyltestosterone

Methyltestosterone, sold under the brand names Android, Metandren, and Testred among others, is an androgen and anabolic steroid (AAS) medication which is used in the treatment of low testosterone levels in men, delayed puberty in boys, at low doses as a component of menopausal hormone therapy for menopausal symptoms like hot flashes, osteoporosis, and low sexual desire in women, and to treat breast cancer in women.

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Nandrolone

Nandrolone, also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin).

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National Institutes of Health

The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.

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Oral administration

| name.

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Orchiectomy

Orchiectomy (also named orchidectomy, and sometimes shortened as orchi) is a surgical procedure in which one or both testicles are removed.

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Organic compound

In chemistry, an organic compound is generally any chemical compound that contains carbon.

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Osteoporosis

Osteoporosis is a disease where increased bone weakness increases the risk of a broken bone.

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Patent

A patent is a set of exclusive rights granted by a sovereign state or intergovernmental organization to an inventor or assignee for a limited period of time in exchange for detailed public disclosure of an invention.

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Pattern hair loss

Pattern hair loss, known as male-pattern hair loss (MPHL) when it affects males and female-pattern hair loss (FPHL) when it affects females, is hair loss that primarily affects the top and front of the scalp.

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Pharmacokinetics

Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism.

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Prodrug

A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug.

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Progesterone

Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.

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Progesterone receptor

The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.

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Progestin

A progestin is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.

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Progestogen

Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).

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Prostate

The prostate (from Ancient Greek προστάτης, prostates, literally "one who stands before", "protector", "guardian") is a compound tubuloalveolar exocrine gland of the male reproductive system in most mammals.

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Prostate cancer

Prostate cancer is the development of cancer in the prostate, a gland in the male reproductive system.

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Self-microemulsifying drug delivery system

A self-microemulsifying drug delivery system (SMEDDS) is a drug delivery system that uses a microemulsion achieved by chemical rather than mechanical means.

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Sexual dysfunction

Sexual dysfunction (or sexual malfunction or sexual disorder) is difficulty experienced by an individual or a couple during any stage of a normal sexual activity, including physical pleasure, desire, preference, arousal or orgasm.

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Side effect

In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.

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Skin

Skin is the soft outer tissue covering vertebrates.

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Spermatogenesis

Spermatogenesis is the process by which haploid spermatozoa develop from germ cells in the seminiferous tubules of the testis.

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Steric effects

Steric effects are nonbonding interactions that influence the shape (conformation) and reactivity of ions and molecules.

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Steroid

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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Substrate (chemistry)

In chemistry, a substrate is typically the chemical species being observed in a chemical reaction, which reacts with a reagent to generate a product.

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Symptom

A symptom (from Greek σύμπτωμα, "accident, misfortune, that which befalls", from συμπίπτω, "I befall", from συν- "together, with" and πίπτω, "I fall") is a departure from normal function or feeling which is noticed by a patient, reflecting the presence of an unusual state, or of a disease.

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Testicle

The testicle or testis is the male reproductive gland in all animals, including humans.

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Testosterone

Testosterone is the primary male sex hormone and an anabolic steroid.

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Testosterone undecanoate

Testosterone undecanoate, sold under the brand names Nebido, Aveed, and Andriol among others, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels in men.

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Tissue (biology)

In biology, tissue is a cellular organizational level between cells and a complete organ.

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Tolerability

Tolerability refers to the degree to which overt adverse effects of a drug can be tolerated by a patient.

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Trestolone

Trestolone, also known as 7α-methyl-19-nortestosterone (MENT), is an experimental androgen/anabolic steroid (AAS) and progestogen medication which has been under development for potential use as a form of hormonal birth control for men and in androgen replacement therapy for low testosterone levels in men but has never been marketed for medical use.

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Trestolone acetate

Trestolone acetate (developmental code names CDB-903, NSC-69948, U-15614; also known as 7α-methyl-19-nortestosterone 17β-acetate and 7α-methylestr-4-en-17β-ol-3-one 17β-acetate) is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was never marketed.

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Undecylic acid

Undecylic acid (systematically named undecanoic acid) is a naturally occurring carboxylic acid with chemical formula CH3(CH2)9COOH.

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United States Department of Health and Human Services

The United States Department of Health and Human Services (HHS), also known as the Health Department, is a cabinet-level department of the U.S. federal government with the goal of protecting the health of all Americans and providing essential human services.

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Weight gain

Weight gain is an increase in body weight.

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11β-Methyl-19-nortestosterone dodecylcarbonate

11β-Methyl-19-nortestosterone 17β-dodecylcarbonate (11β-MNTDC) (developmental code name CDB-4754) is a synthetic and orally active anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was developed by the Contraceptive Development Branch (CDB) of the National Institute of Child Health and Human Development (NICHD) and has not been marketed for medical use at this time.

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17α-Alkylated anabolic steroid

A 17α-alkylated anabolic steroid is a synthetic anabolic–androgenic steroid (AAS) that features an alkyl group, specifically a methyl or ethyl group, at the C17α position.

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5α-Reductase

5α-reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism.

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Redirects here:

7α,11β-Dimethyl-19-nortestosterone 17β-undecanoate, 7α,11β-Dimethyl-19-nortestosterone undecanoate, 7α,11β-dimethyl-19-nortestosterone 17β-undecanoate, 7α,11β-dimethyl-19-nortestosterone undecanoate, C31H50O3, CDB 4521, CDB-4521, CDB4521, DMAU, DMAU undecanoate, DMAU undecylate, Dimethandrolone undecylate.

References

[1] https://en.wikipedia.org/wiki/Dimethandrolone_undecanoate

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