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45 relations: Acute myeloid leukemia, Auditory brainstem response, Beta-catenin, Cellular differentiation, Clinical chemistry, DNA methyltransferase, DNMT1, DNMT3B, Dual-energy X-ray absorptiometry, Embryogenesis, Enzyme, Epigenetics, Exon shuffling, Gene, Genomic imprinting, Glucose tolerance test, HDAC1, Hematology, Hematopoietic stem cell, Heterochromatin, Homology (biology), Indirect calorimetry, Isogenic human disease models, Knockout mouse, Model organism, Murinae, Myc, Phenotypic screening, PIAS1, Prokaryote, Protein inhibitor of activated STAT2, Protein–protein interaction, Radiography, RNA splicing, Salmonella, SUV39H1, Teratology, The Cancer Genome Atlas, Transcriptional regulation, Transcriptome instability, UBE2I, Wellcome Sanger Institute, X-inactivation, ZNF238, Zygosity.
Acute myeloid leukemia
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells.
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Auditory brainstem response
The auditory brainstem response (ABR) is an auditory evoked potential extracted from ongoing electrical activity in the brain and recorded via electrodes placed on the scalp.
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Beta-catenin
Catenin beta-1, also known as β-catenin, is a protein that in humans is encoded by the CTNNB1 gene.
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Cellular differentiation
In developmental biology, cellular differentiation is the process where a cell changes from one cell type to another.
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Clinical chemistry
Clinical chemistry (also known as chemical pathology, clinical biochemistry or medical biochemistry) is the area of chemistry that is generally concerned with analysis of bodily fluids for diagnostic and therapeutic purposes.
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DNA methyltransferase
In biochemistry, the DNA methyltransferase (DNA MTase) family of enzymes catalyze the transfer of a methyl group to DNA.
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DNMT1
DNA (cytosine-5)-methyltransferase 1 is an enzyme that catalyzes the transfer of methyl groups to specific CpG structures in DNA, a process called DNA methylation.
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DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta, also known as DNMT3B, is a protein associated with immunodeficiency, centromere instability and facial anomalies syndrome.
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Dual-energy X-ray absorptiometry
Dual-energy X-ray absorptiometry (DXA, previously DEXA) is a means of measuring bone mineral density (BMD).
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Embryogenesis
Embryogenesis is the process by which the embryo forms and develops.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Epigenetics
Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence.
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Exon shuffling
--> Exon shuffling is a molecular mechanism for the formation of new genes.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Genomic imprinting
Genomic imprinting is an epigenetic phenomenon that causes genes to be expressed in a parent-of-origin-specific manner.
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Glucose tolerance test
The glucose tolerance test is a medical test in which glucose is given and blood samples taken afterward to determine how quickly it is cleared from the blood.
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HDAC1
Histone deacetylase 1 (HDAC1) is an enzyme that in humans is encoded by the HDAC1 gene.
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Hematology
Hematology, also spelled haematology, is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood.
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Hematopoietic stem cell
Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells.
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Heterochromatin
Heterochromatin is a tightly packed form of DNA or condensed DNA, which comes in multiple varieties.
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Homology (biology)
In biology, homology is the existence of shared ancestry between a pair of structures, or genes, in different taxa.
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Indirect calorimetry
Indirect calorimetry calculates heat that living organisms produce by measuring either their production of carbon dioxide and nitrogen waste (frequently ammonia in aquatic organisms, or urea in terrestrial ones), or from their consumption of oxygen.
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Isogenic human disease models
Isogenic human disease models are a family of cells that are selected or engineered to accurately model the genetics of a specific patient population, in vitro.
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Knockout mouse
A knockout mouse or knock-out mouse is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA.
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Model organism
A model organism is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the organism model will provide insight into the workings of other organisms.
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Murinae
The Old World rats and mice, part of the subfamily Murinae in the family Muridae, comprise at least 519 species.
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Myc
Myc is a family of regulator genes and proto-oncogenes that code for transcription factors.
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Phenotypic screening
Phenotypic screening is a type of screening used in biological research and drug discovery to identify substances such as small molecules, peptides, or RNAi that alter the phenotype of a cell or an organism in a desired manner.
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PIAS1
E3 SUMO-protein ligase PIAS1 is an enzyme that in humans is encoded by the PIAS1 gene.
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Prokaryote
A prokaryote is a unicellular organism that lacks a membrane-bound nucleus, mitochondria, or any other membrane-bound organelle.
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Protein inhibitor of activated STAT2
E3 SUMO-protein ligase PIAS2 is an enzyme that in humans is encoded by the PIAS2 gene.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Radiography
Radiography is an imaging technique using X-rays to view the internal form of an object.
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RNA splicing
In molecular biology, splicing is the editing of the nascent precursor messenger RNA (pre-mRNA) transcript into a mature messenger RNA (mRNA).
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Salmonella
Salmonella is a genus of rod-shaped (bacillus) Gram-negative bacteria of the family Enterobacteriaceae.
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SUV39H1
Histone-lysine N-methyltransferase SUV39H1 is an enzyme that in humans is encoded by the SUV39H1 gene.
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Teratology
Teratology is the study of abnormalities of physiological development.
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The Cancer Genome Atlas
The Cancer Genome Atlas (TCGA) is a project, begun in 2005, to catalogue genetic mutations responsible for cancer, using genome sequencing and bioinformatics.
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Transcriptional regulation
In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity.
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Transcriptome instability
Transcriptome instability is a genome-wide, pre-mRNA splicing-related characteristic of certain cancers.
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UBE2I
SUMO-conjugating enzyme UBC9 is an enzyme that in humans is encoded by the UBE2I gene.
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Wellcome Sanger Institute
The Wellcome Sanger Institute, previously known as The Sanger Centre and Wellcome Trust Sanger Institute, is a non-profit British genomics and genetics research institute, primarily funded by the Wellcome Trust.
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X-inactivation
X-inactivation (also called lyonization) is a process by which one of the copies of the X chromosome present in female mammals is inactivated.
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ZNF238
Zinc finger protein 238 is a protein that in humans is encoded by the ZNF238 gene.
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Zygosity
Zygosity is the degree of similarity of the alleles for a trait in an organism.
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Redirects here:
DNMT3A, DNMT3A (gene), DNMT3a.
References
[1] https://en.wikipedia.org/wiki/DNA_(cytosine-5)-methyltransferase_3A
