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32 relations: Argonaute, Base pair, Breast cancer, Caenorhabditis elegans, Carcinogenesis, Cell nucleus, Colorectal cancer, Cytoplasm, DGCR8, Dicer, DNA repair, Drosophila, Endoribonuclease, Enzyme, Esophageal cancer, Eukaryote, Gene, Master regulator, Messenger RNA, Microprocessor complex, MicroRNA, Nuclease, Primary transcript, Prokaryote, Protein complex, Ribonuclease III, Ribosomal RNA, RNA, RNA interference, RNA-induced silencing complex, Stem-loop, The Cancer Genome Atlas.
Argonaute
The Argonaute protein family plays a central role in RNA silencing processes, as essential components of the RNA-induced silencing complex (RISC).
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Base pair
A base pair (bp) is a unit consisting of two nucleobases bound to each other by hydrogen bonds.
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Breast cancer
Breast cancer is cancer that develops from breast tissue.
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Caenorhabditis elegans
Caenorhabditis elegans is a free-living (not parasitic), transparent nematode (roundworm), about 1 mm in length, that lives in temperate soil environments.
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Carcinogenesis
Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells.
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Cell nucleus
In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.
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Colorectal cancer
Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine).
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Cytoplasm
In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.
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DGCR8
The DGCR8 microprocessor complex subunit (DiGeorge syndrome chromosomal region 8) is a protein that in humans is encoded by the DGCR8 gene.
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Dicer
Dicer, also known as endoribonuclease Dicer or helicase with RNase motif, is an enzyme that in humans is encoded by the DICER1 gene.
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DNA repair
DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome.
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Drosophila
Drosophila is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit.
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Endoribonuclease
An Endoribonuclease is a ribonuclease endonuclease.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Esophageal cancer
Esophageal cancer is cancer arising from the esophagus—the food pipe that runs between the throat and the stomach.
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Eukaryote
Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Master regulator
In genetics, a master regulator is a gene at the top of a gene regulation hierarchy, particularly in regulatory pathways related to cell fate and differentiation.
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Messenger RNA
Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
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Microprocessor complex
The Microprocessor complex is a protein complex involved in the early stages of processing microRNA (miRNA) in animal cells.
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MicroRNA
A microRNA (abbreviated miRNA) is a small non-coding RNA molecule (containing about 22 nucleotides) found in plants, animals and some viruses, that functions in RNA silencing and post-transcriptional regulation of gene expression.
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Nuclease
A nuclease (also archaically known as nucleodepolymerase or polynucleotidase) is an enzyme capable of cleaving the phosphodiester bonds between monomers of nucleic acids.
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Primary transcript
A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs.
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Prokaryote
A prokaryote is a unicellular organism that lacks a membrane-bound nucleus, mitochondria, or any other membrane-bound organelle.
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Protein complex
A protein complex or multiprotein complex is a group of two or more associated polypeptide chains.
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Ribonuclease III
Ribonuclease III (RNase III or RNase C)(BRENDA) is a type of ribonuclease that recognizes dsRNA and cleaves it at specific targeted locations to transform them into mature RNAs.
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Ribosomal RNA
Ribosomal ribonucleic acid (rRNA) is the RNA component of the ribosome, and is essential for protein synthesis in all living organisms.
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RNA
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.
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RNA interference
RNA interference (RNAi) is a biological process in which RNA molecules inhibit gene expression or translation, by neutralizing targeted mRNA molecules.
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RNA-induced silencing complex
The RNA-induced silencing complex, or RISC, is a multiprotein complex, specifically a ribonucleoprotein, which incorporates one strand of a single-stranded RNA (ssRNA) fragment, such as microRNA (miRNA), or double-stranded small interfering RNA (siRNA).
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Stem-loop
Stem-loop intramolecular base pairing is a pattern that can occur in single-stranded DNA or, more commonly, in RNA.
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The Cancer Genome Atlas
The Cancer Genome Atlas (TCGA) is a project, begun in 2005, to catalogue genetic mutations responsible for cancer, using genome sequencing and bioinformatics.
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Redirects here:
DROSHA, DROSHA (gene), Drosha ribonuclease III, RNASEN.
References
[1] https://en.wikipedia.org/wiki/Drosha
