Foliglurax

Foliglurax (developmental code names PXT-002331, DT-1687) is a positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4) which is under development by Prexton Therapeutics for the treatment of Parkinson's disease. ^[1]

4 relations: Allosteric modulator, Clinical trial, Metabotropic glutamate receptor 4, Parkinson's disease.

Allosteric modulator

In biochemistry and pharmacology, an allosteric modulator (allo- from the Greek meaning "other") is a substance which indirectly influences (modulates) the effects of a primary ligand that directly activates or deactivates the function of a target protein.

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Clinical trial

Clinical trials are experiments or observations done in clinical research.

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Metabotropic glutamate receptor 4

Metabotropic glutamate receptor 4 is a protein that in humans is encoded by the GRM4 gene.

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Parkinson's disease

Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system.

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Redirects here:

DT 1687, DT-1687, DT1687, PXT 002331, PXT 2331, PXT-002331, PXT-2331, PXT002331, PXT2331.

References

[1] https://en.wikipedia.org/wiki/Foliglurax

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