Daf-12

The DAF-12 (abnormal dauer formation protein 12) gene encodes the nuclear receptor of dafachronic acid (a steroid hormone) in the worm Caenorhabditis elegans, with the NRNC Symbol NR1J1 as the homolog of nuclear hormone receptor HR96 in Drosophila melanogaster. ^[1]

16 relations: Caenorhabditis elegans, Cynthia Kenyon, Cytochrome P450, Daf-9, Dafachronic acid, Dauer larva, Development (journal), Drosophila melanogaster, Frontiers in Endocrinology, Gene, Hormone, Nature (journal), Nuclear receptor, PLOS One, Repressor, Steroid.
Caenorhabditis elegans genes
Nuclear receptors

Caenorhabditis elegans

Caenorhabditis elegans is a free-living transparent nematode about 1 mm in length that lives in temperate soil environments.

See Daf-12 and Caenorhabditis elegans

Cynthia Kenyon

Cynthia Jane Kenyon (born February 21, 1954) is an American molecular biologist and biogerontologist known for her genetic dissection of aging in a widely used model organism, the roundworm Caenorhabditis elegans.

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Cytochrome P450

Cytochromes P450 (P450s or CYPs) are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases.

See Daf-12 and Cytochrome P450

Daf-9

The Daf-9 gene encodes a cytochrome p450 enzyme catalysis the generation of dafachronic acid (a steroid hormone) in the worm Caenorhabditis elegans, with the CYP Symbol CYP22A1 (Cytochrome P450, family 22, member A1). Daf-12 and daf-9 are Caenorhabditis elegans genes.

See Daf-12 and Daf-9

Dafachronic acid

Dafachronic acids are steroid hormones activate the nuclear receptor Daf-12/NR1J1 in Caenorhabditis elegans and related organisms, include Δ4-dafachronic acid and Δ7-dafachronic acid.

See Daf-12 and Dafachronic acid

Dauer larva

Dauer (German "", English "the enduring", "the duration" in the meaning of "a length of time") describes an alternative developmental stage of nematode worms, particularly rhabditids including Caenorhabditis elegans, whereby the larva goes into a type of stasis and can survive harsh conditions.

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Development (journal)

Development is a bi-weekly peer-reviewed scientific journal in the field of developmental biology that covers cellular and molecular mechanisms of animal and plant development.

See Daf-12 and Development (journal)

Drosophila melanogaster

Drosophila melanogaster is a species of fly (an insect of the order Diptera) in the family Drosophilidae.

See Daf-12 and Drosophila melanogaster

Frontiers in Endocrinology

Frontiers in Endocrinology is a peer-reviewed open access scientific journal covering all aspects of endocrinology in 21 sections.

See Daf-12 and Frontiers in Endocrinology

Gene

In biology, the word gene has two meanings.

See Daf-12 and Gene

Hormone

A hormone (from the Greek participle ὁρμῶν, "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physiology and behavior.

See Daf-12 and Hormone

Nature (journal)

Nature is a British weekly scientific journal founded and based in London, England.

See Daf-12 and Nature (journal)

Nuclear receptor

In the field of molecular biology, nuclear receptors are a class of proteins responsible for sensing steroids, thyroid hormones, vitamins, and certain other molecules. Daf-12 and nuclear receptor are nuclear receptors.

See Daf-12 and Nuclear receptor

PLOS One

PLOS One (stylized PLOS ONE, and formerly PLoS ONE) is a peer-reviewed open access mega journal published by the Public Library of Science (PLOS) since 2006.

See Daf-12 and PLOS One

Repressor

In molecular genetics, a repressor is a DNA- or RNA-binding protein that inhibits the expression of one or more genes by binding to the operator or associated silencers.

See Daf-12 and Repressor

Steroid

A steroid is an organic compound with four fused rings (designated A, B, C, and D) arranged in a specific molecular configuration.

See Daf-12 and Steroid

References

[1] https://en.wikipedia.org/wiki/Daf-12

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