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Index Demegestone

Demegestone, sold under the brand name Lutionex, is a progestin medication which was previously used to treat luteal insufficiency but is now no longer marketed. [1]

56 relations: Agonist, Aldosterone, Androgen, Antiandrogen, Antiglucocorticoid, Aromatization, Bioassay, Bioavailability, Biological half-life, Biological target, Carl Clauberg, Clearance (pharmacology), Decidualization, Dehydration, Deoxycorticosterone, Derivative (chemistry), Estradiol (medication), Estrogen (medication), Excretion, France, Glucocorticoid, Glucocorticoid receptor, Hydrocortisone, Hydroxy group, Hydroxylation, Infertility, Intravenous therapy, Ligand (biochemistry), Luteal phase, Metabolism, Metabolite, Mineralocorticoid, Moxestrol, Oral administration, Oral contraceptive pill, Organic compound, Ovulation, Pharmacodynamics, Potency (pharmacology), Progesterone, Progesterone (medication), Progesterone receptor, Progestin, Progestogen, Promegestone, Roussel Uclaf, Steroid, Testosterone (medication), Trademark distinctiveness, Trimegestone, ..., Urine, Volume of distribution, 17α-Methyl-19-norprogesterone, 17α-Methylprogesterone, 19-Norpregnane, 19-Norprogesterone. Expand index (6 more) »


An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.

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An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.

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Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body.

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An antiglucocorticoid is a drug which reduces glucocorticoid activity in the body.

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Aromatization is a chemical reaction in which an aromatic system is formed.

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A bioassay is an analytical method to determine concentration or potency of a substance by its effect on living cells or tissues.

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In pharmacology, bioavailability (BA or F) is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.

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Biological half-life

The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.

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Biological target

A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function.

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Carl Clauberg

Carl Clauberg (28 September 1898 – 9 August 1957) was a German gynecologist who conducted medical experiments on human subjects (mainly Jewish) at Auschwitz concentration camp.

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Clearance (pharmacology)

In pharmacology, the clearance is a pharmacokinetic measurement of the volume of plasma from which a substance is completely removed per unit time; the usual units are mL/min.

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Decidualization is a process that results in significant changes to cells of the endometrium in preparation for, and during, pregnancy.

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In physiology, dehydration is a deficit of total body water, with an accompanying disruption of metabolic processes.

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Deoxycorticosterone (DOC), or desoxycorticosterone, may refer to.

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Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

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Estradiol (medication)

Estradiol, also spelled oestradiol, is a medication and naturally occurring steroid hormone.

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Estrogen (medication)

An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.

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Excretion is the process by which metabolic waste is eliminated from an organism.

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France, officially the French Republic (République française), is a sovereign state whose territory consists of metropolitan France in Western Europe, as well as several overseas regions and territories.

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Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones.

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Glucocorticoid receptor

The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind.

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Hydrocortisone, sold under a number of brand names, is the name for the hormone cortisol when supplied as a medication.

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Hydroxy group

A hydroxy or hydroxyl group is the entity with the formula OH.

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Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound.

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Infertility is the inability of a person, animal or plant to reproduce by natural means.

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Intravenous therapy

Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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Luteal phase

The luteal phase is the latter phase of the menstrual cycle (in humans and a few other animals) or the earlier phase of the estrous cycle (in other placental mammals).

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Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.

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A metabolite is the intermediate end product of metabolism.

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Mineralocorticoids are a class of corticosteroids, which in turn are a class of steroid hormones.

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Moxestrol, sold under the brand name Surestryl, is an estrogen medication which is or was used in Europe for the treatment of menopausal symptoms and menstrual disorders.

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Oral administration

| name.

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Oral contraceptive pill

Oral contraceptives, abbreviated OCPs, also known as birth control pills, are medications taken by mouth for the purpose of birth control.

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Organic compound

In chemistry, an organic compound is generally any chemical compound that contains carbon.

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Ovulation is the release of eggs from the ovaries.

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Pharmacodynamics is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).

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Potency (pharmacology)

In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.

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Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.

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Progesterone (medication)

Progesterone is a medication and naturally occurring steroid hormone.

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Progesterone receptor

The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.

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A progestin is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.

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Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).

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Promegestone, sold under the brand name Surgestone, is a progestin medication which is used in menopausal hormone therapy and in the treatment of gynecological disorders.

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Roussel Uclaf

Roussel Uclaf S.A. was a French pharmaceutical company and one of several predecessor companies of today's Sanofi.

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A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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Testosterone (medication)

Testosterone is a medication and naturally occurring steroid hormone.

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Trademark distinctiveness

Trademark distinctiveness is an important concept in the law governing trademarks and service marks.

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Trimegestone, sold under the brand names Ondeva and Totelle among others, is a progestin medication which is used in menopausal hormone therapy and in the prevention of postmenopausal osteoporosis.

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Urine is a liquid by-product of metabolism in humans and in many animals.

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Volume of distribution

In pharmacology, the volume of distribution (VD, also known as apparent volume of distribution) is the theoretical volume that would be necessary to contain the total amount of an administered drug at the same concentration that it is observed in the blood plasma.

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17α-Methyl-19-norprogesterone (developmental code name H-3510), also known as 17α-methyl-19-norpregn-4-ene-3,20-dione, is a progestin which was never marketed.

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17α-Methylprogesterone (17α-MP), or 17α-methylpregn-4-ene-3,20-dione, is a steroidal progestin related to progesterone that was synthesized and characterized in 1949 but was never marketed.

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19-Norpregnane, also known as 13β-methyl-17β-ethylgonane, is a norsteroid and the 19-demethyl analogue of pregnane.

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19-Norprogesterone, also known as 19-norpregn-4-ene-3,20-dione, is a steroidal progestin and close analogue of the sex hormone progesterone, lacking only the C19 methyl group of that molecule.

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Redirects here:

ATC code G03DB05, ATCvet code QG03DB05, Dimegestone, Lutionex, R 2353, R 2453, R-2353, R-2453, R2353, R2453, RU 2353, RU 2453, RU-2353, RU-2453, RU2353, RU2453.


[1] https://en.wikipedia.org/wiki/Demegestone

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