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Dihydrodipicolinate synthase

Index Dihydrodipicolinate synthase

4-Hydroxy-tetrahydrodipicolinate synthase (dihydrodipicolinate synthase, dihydropicolinate synthetase, dihydrodipicolinic acid synthase, L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing), dapA (gene)) is an enzyme with the systematic name L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing; (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinate-forming). [1]

24 relations: Active site, Alpha helix, C-terminus, Catalysis, Chemical reaction, Enzyme, Escherichia coli, List of enzymes, Lyase, Lysine, Monomer, N-acetylneuraminate lyase, N-Acetylneuraminic acid, Phycomycetes, Prokaryote, Protein, Protein folding, Pyruvic acid, Schiff base, Sequence (biology), Sinorhizobium meliloti, Structure, Symmetry, Vascular plant.

Active site

In biology, the active site is the region of an enzyme where substrate molecules bind and undergo a chemical reaction.

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Alpha helix

The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a righthand-spiral conformation (i.e. helix) in which every backbone N−H group donates a hydrogen bond to the backbone C.

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C-terminus

The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).

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Catalysis

Catalysis is the increase in the rate of a chemical reaction due to the participation of an additional substance called a catalysthttp://goldbook.iupac.org/C00876.html, which is not consumed in the catalyzed reaction and can continue to act repeatedly.

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Chemical reaction

A chemical reaction is a process that leads to the transformation of one set of chemical substances to another.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Escherichia coli

Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).

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List of enzymes

This page lists enzymes by their classification in the International Union of Biochemistry and Molecular Biology's Enzyme Commission numbering system.

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Lyase

In biochemistry, a lyase is an enzyme that catalyzes the breaking (an "elimination" reaction) of various chemical bonds by means other than hydrolysis (a "substitution" reaction) and oxidation, often forming a new double bond or a new ring structure.

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Lysine

Lysine (symbol Lys or K) is an α-amino acid that is used in the biosynthesis of proteins.

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Monomer

A monomer (mono-, "one" + -mer, "part") is a molecule that "can undergo polymerization thereby contributing constitutional units to the essential structure of a macromolecule".

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N-acetylneuraminate lyase

In enzymology, a N-acetylneuraminate lyase is an enzyme that catalyzes the chemical reaction Hence, this enzyme has one substrate, N-acetylneuraminate, and two products, N-acetyl-D-mannosamine and pyruvate.

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N-Acetylneuraminic acid

N-Acetylneuraminic acid (Neu5Ac or NANA) is the predominant sialic acid found in mammalian cells.

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Phycomycetes

Phycomycetes is an obsolete polyphyletic taxon for certain fungi with nonseptate hyphae.

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Prokaryote

A prokaryote is a unicellular organism that lacks a membrane-bound nucleus, mitochondria, or any other membrane-bound organelle.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein folding

Protein folding is the physical process by which a protein chain acquires its native 3-dimensional structure, a conformation that is usually biologically functional, in an expeditious and reproducible manner.

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Pyruvic acid

Pyruvic acid (CH3COCOOH) is the simplest of the alpha-keto acids, with a carboxylic acid and a ketone functional group.

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Schiff base

A Schiff base (named after Hugo Schiff) is a compound with the general structure R2C.

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Sequence (biology)

A sequence in biology is the one-dimensional ordering of monomers, covalently linked within a biopolymer; it is also referred to as the primary structure of the biological macromolecule.

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Sinorhizobium meliloti

Sinorhizobium meliloti is a Gram-negative nitrogen-fixing bacterium (rhizobium).

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Structure

Structure is an arrangement and organization of interrelated elements in a material object or system, or the object or system so organized.

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Symmetry

Symmetry (from Greek συμμετρία symmetria "agreement in dimensions, due proportion, arrangement") in everyday language refers to a sense of harmonious and beautiful proportion and balance.

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Vascular plant

Vascular plants (from Latin vasculum: duct), also known as tracheophytes (from the equivalent Greek term trachea) and also higher plants, form a large group of plants (c. 308,312 accepted known species) that are defined as those land plants that have lignified tissues (the xylem) for conducting water and minerals throughout the plant.

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Redirects here:

4-hydroxy-tetrahydrodipicolinate synthase, DHDPS, DapA (gene), Dihydrodipicolinate synthase (version 2), Dihydrodipicolinic acid synthase, Dihydropicolinate synthetase, EC 4.2.1.52, EC 4.3.3.7, L-aspartate-4-semialdehyde hydro-lyase, L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing), L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing; (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinate-forming).

References

[1] https://en.wikipedia.org/wiki/Dihydrodipicolinate_synthase

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