35 relations: ABVD, Alkylating antineoplastic agent, Allergy, Aprepitant, Bayer, Bleomycin, Boxed warning, Chemotherapy, Chemotherapy regimen, Chemotherapy-induced nausea and vomiting, Developing country, Dexamethasone, Diazomethane, Doxorubicin, Generic drug, Health system, History of cancer chemotherapy, Hodgkin's lymphoma, Hospira, Intravenous therapy, Kidney, Leukopenia, Liver disease, Melanoma, Metastasis, National Health Service, NK1 receptor antagonist, Ondansetron, Pregnancy, Purine analogue, Teva Pharmaceutical Industries, Thrombocytopenia, Vinblastine, WHO Model List of Essential Medicines, 5-HT3 antagonist.
ABVD
ABVD is a chemotherapy regimen used in the first-line treatment of Hodgkin lymphoma, supplanting the older MOPP protocol.
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Alkylating antineoplastic agent
An alkylating antineoplastic agent is an alkylating agent used in cancer treatment that attaches an alkyl group (CnH2n+1) to DNA.
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Allergy
Allergies, also known as allergic diseases, are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment.
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Aprepitant
Aprepitant (brand name: Emend (the brand name used in all English-speaking countries)) is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA).
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Bayer
Bayer AG is a German multinational, pharmaceutical and life sciences company.
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Bleomycin
Bleomycin is a medication used to treat cancer. This includes Hodgkin's lymphoma, non-Hodgkin's lymphoma, testicular cancer, ovarian cancer, and cervical cancer among others. Typically used with other cancer medications, it can be given intravenously, by injection into a muscle or under the skin. It may also be administered inside the chest to help prevent the recurrence of a fluid around the lung due to cancer; however talc is better for this. Common side effects include fever, weight loss, vomiting, and rash. A severe type of anaphylaxis may occur. It may also cause inflammation of the lungs that can result in lung scarring. Chest X-rays every couple of weeks are recommended to check for this. Bleomycin may cause harm to the baby if used during pregnancy. It is believed to primarily work by preventing the making of DNA. Bleomycin was discovered in 1962. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. It is available as a generic medication. The wholesale cost in the developing world is between 14 USD and 78 USD a dose. It is made by the bacterium Streptomyces verticillus.
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Boxed warning
In the United States, a boxed warning (sometimes "black box warning", colloquially) is a type of warning that appears on the package insert for certain prescription drugs, so called because the U.S. Food and Drug Administration specifies that it is formatted with a 'box' or border around the text.
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.
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Chemotherapy regimen
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations.
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Chemotherapy-induced nausea and vomiting
Chemotherapy-induced nausea and vomiting (CINV) is a common side-effect of many cancer treatments.
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Developing country
A developing country (or a low and middle income country (LMIC), less developed country, less economically developed country (LEDC), underdeveloped country) is a country with a less developed industrial base and a low Human Development Index (HDI) relative to other countries.
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Dexamethasone
Dexamethasone is a type of corticosteroid medication.
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Diazomethane
Diazomethane is the chemical compound CH2N2, discovered by German chemist Hans von Pechmann in 1894.
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Doxorubicin
Doxorubicin, sold under the trade names Adriamycin among others, is a chemotherapy medication used to treat cancer.
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Generic drug
A generic drug is a pharmaceutical drug that is equivalent to a brand-name product in dosage, strength, route of administration, quality, performance, and intended use, but does not carry the brand name.
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Health system
A health system, also sometimes referred to as health care system or as healthcare system, is the organization of people, institutions, and resources that deliver health care services to meet the health needs of target populations.
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History of cancer chemotherapy
The era of cancer chemotherapy began in the 1940s with the first use of nitrogen mustards and folic acid antagonist drugs.
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Hodgkin's lymphoma
Hodgkin's lymphoma (HL) is a type of lymphoma which is generally believed to result from white blood cells of the lymphocyte kind.
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Hospira
Hospira was an American global pharmaceutical and medical device company with headquarters in Lake Forest, Illinois.
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Intravenous therapy
Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).
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Kidney
The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.
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Leukopenia
Leukopenia is a decrease in the number of white blood cells (leukocytes) found in the blood, which places individuals at increased risk of infection.
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Liver disease
Liver disease (also called hepatic disease) is a type of damage to or disease of the liver.
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Melanoma
Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes.
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Metastasis
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.
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National Health Service
The National Health Service (NHS) is the name used for each of the public health services in the United Kingdom – the National Health Service in England, NHS Scotland, NHS Wales, and Health and Social Care in Northern Ireland – as well as a term to describe them collectively.
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NK1 receptor antagonist
Neurokinin 1 (NK1) antagonists are a novel class of medications that possesses unique antidepressant, anxiolytic, and antiemetic properties.
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Ondansetron
Ondansetron, marketed under the brand name Zofran, is a medication used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, or surgery.
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Pregnancy
Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.
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Purine analogue
Purine analogues are antimetabolites that mimic the structure of metabolic purines.
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Teva Pharmaceutical Industries
Teva Pharmaceutical Industries Ltd. (טבע תעשיות פרמצבטיות בע"מ) is an Israeli multinational pharmaceutical company headquartered in Petah Tikva, Israel.
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Thrombocytopenia
Thrombocytopenia is a condition characterized by abnormally low levels of thrombocytes, also known as platelets, in the blood.
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Vinblastine
Vinblastine is a chemotherapy medication, typically used with other medications, to treat a number of types of cancer.
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WHO Model List of Essential Medicines
The WHO Model List of Essential Medicines (EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.
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5-HT3 antagonist
The 5-HT3 antagonists, informally known as "setrons", are a class of drugs that act as receptor antagonists at the 5-HT3 receptor, a subtype of serotonin receptor found in terminals of the vagus nerve and in certain areas of the brain.
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Redirects here:
ATC code L01AX04, ATCvet code QL01AX04, C6H10N6O, Deticene, Dtic-Dome.
References
[1] https://en.wikipedia.org/wiki/Dacarbazine