Get it on Google Play
New! Download Unionpedia on your Android™ device!
Faster access than browser!


Index E2F

E2F is a group of genes that codifies a family of transcription factors (TF) in higher eukaryotes. [1]

46 relations: Adenoviridae, Binding site, BRCA1, C-terminus, Caspase, Cdc6, Cell cycle, Cyclin, Cyclin A, Cyclin D, Cyclin-dependent kinase, Cyclin-dependent kinase 1, Cyclin-dependent kinase 4, Cyclin-dependent kinase 6, Dihydrofolate reductase, DNA microarray, DNA polymerase, DNA repair, DNA-binding domain, Eukaryote, Growth factor, Histone, Histone deacetylase, Human papillomavirus infection, Mammal, MAPK/ERK pathway, MCM5, N-terminus, National Center for Biotechnology Information, P53, Phosphorylation, Pocket protein family, Polycomb-group proteins, Proliferating cell nuclear antigen, Promoter (genetics), Protein domain, Protein primary structure, Retinoblastoma protein, TFDP1, TFDP2, Thymidine kinase, Transcription factor, Transcription factor DP, Type 3c (Pancreatogenic) Diabetes, Winged-helix transcription factors, X-ray crystallography.


Adenoviruses (members of the family Adenoviridae) are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double stranded DNA genome.

New!!: E2F and Adenoviridae · See more »

Binding site

In biochemistry, a binding site is a region on a protein or piece of DNA or RNA to which ligands (specific molecules and/or ions) may form a chemical bond.

New!!: E2F and Binding site · See more »


BRCA1 and BRCA1 are a human gene and its protein product, respectively.

New!!: E2F and BRCA1 · See more »


The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).

New!!: E2F and C-terminus · See more »


Caspases (cysteine-aspartic proteases, cysteine aspartases or cysteine-dependent aspartate-directed proteases) are a family of protease enzymes playing essential roles in programmed cell death (including apoptosis, pyroptosis and necroptosis) and inflammation.

New!!: E2F and Caspase · See more »


Cdc6, or cell division cycle 6, is a protein in eukaryotic cells that is studied in the budding yeast Saccharomyces cerevisiae.

New!!: E2F and Cdc6 · See more »

Cell cycle

The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.

New!!: E2F and Cell cycle · See more »


Cyclin is a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (Cdk) enzymes.

New!!: E2F and Cyclin · See more »

Cyclin A

Cyclin A is a member of the cyclin family, a group of proteins that function in regulating progression through the cell cycle.

New!!: E2F and Cyclin A · See more »

Cyclin D

Cyclin D is a member of the cyclin protein family that is involved in regulating cell cycle progression.

New!!: E2F and Cyclin D · See more »

Cyclin-dependent kinase

Gap phase 2. The duration of mitosis in relation to the other phases has been exaggerated in this diagram Cyclin-dependent kinases (CDKs) are a family of sugar kinases first discovered for their role in regulating the cell cycle.

New!!: E2F and Cyclin-dependent kinase · See more »

Cyclin-dependent kinase 1

Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine kinase, and is a key player in cell cycle regulation.

New!!: E2F and Cyclin-dependent kinase 1 · See more »

Cyclin-dependent kinase 4

Cyclin-dependent kinase 4 also known as cell division protein kinase 4 is an enzyme that in humans is encoded by the CDK4 gene.

New!!: E2F and Cyclin-dependent kinase 4 · See more »

Cyclin-dependent kinase 6

Cell division protein kinase 6 (CDK6) is an enzyme encoded by the CDK6 gene.

New!!: E2F and Cyclin-dependent kinase 6 · See more »

Dihydrofolate reductase

Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in 1-carbon transfer chemistry.

New!!: E2F and Dihydrofolate reductase · See more »

DNA microarray

A DNA microarray (also commonly known as DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid surface.

New!!: E2F and DNA microarray · See more »

DNA polymerase

DNA polymerases are enzymes that synthesize DNA molecules from deoxyribonucleotides, the building blocks of DNA.

New!!: E2F and DNA polymerase · See more »

DNA repair

DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome.

New!!: E2F and DNA repair · See more »

DNA-binding domain

A DNA-binding domain (DBD) is an independently folded protein domain that contains at least one structural motif that recognizes double- or single-stranded DNA.

New!!: E2F and DNA-binding domain · See more »


Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).

New!!: E2F and Eukaryote · See more »

Growth factor

A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation.

New!!: E2F and Growth factor · See more »


In biology, histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes.

New!!: E2F and Histone · See more »

Histone deacetylase

Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups (O.

New!!: E2F and Histone deacetylase · See more »

Human papillomavirus infection

Human papillomavirus infection is an infection by human papillomavirus (HPV).

New!!: E2F and Human papillomavirus infection · See more »


Mammals are the vertebrates within the class Mammalia (from Latin mamma "breast"), a clade of endothermic amniotes distinguished from reptiles (including birds) by the possession of a neocortex (a region of the brain), hair, three middle ear bones, and mammary glands.

New!!: E2F and Mammal · See more »

MAPK/ERK pathway

The MAPK/ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the surface of the cell to the DNA in the nucleus of the cell.

New!!: E2F and MAPK/ERK pathway · See more »


DNA replication licensing factor MCM5 is a protein that in humans is encoded by the MCM5 gene.

New!!: E2F and MCM5 · See more »


The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.

New!!: E2F and N-terminus · See more »

National Center for Biotechnology Information

The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health (NIH).

New!!: E2F and National Center for Biotechnology Information · See more »


Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice).

New!!: E2F and P53 · See more »


In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.

New!!: E2F and Phosphorylation · See more »

Pocket protein family

Pocket protein family consists of three proteins.

New!!: E2F and Pocket protein family · See more »

Polycomb-group proteins

Polycomb-group proteins are a family of proteins first discovered in fruit flies that can remodel chromatin such that epigenetic silencing of genes takes place.

New!!: E2F and Polycomb-group proteins · See more »

Proliferating cell nuclear antigen

Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication.

New!!: E2F and Proliferating cell nuclear antigen · See more »

Promoter (genetics)

In genetics, a promoter is a region of DNA that initiates transcription of a particular gene.

New!!: E2F and Promoter (genetics) · See more »

Protein domain

A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.

New!!: E2F and Protein domain · See more »

Protein primary structure

Protein primary structure is the linear sequence of amino acids in a peptide or protein.

New!!: E2F and Protein primary structure · See more »

Retinoblastoma protein

The retinoblastoma protein (protein name abbreviated pRb; gene name abbreviated RB or RB1) is a tumor suppressor protein that is dysfunctional in several major cancers.

New!!: E2F and Retinoblastoma protein · See more »


Transcription factor Dp-1 is a protein that in humans is encoded by the TFDP1 gene.

New!!: E2F and TFDP1 · See more »


Transcription factor Dp-2 is a protein that in humans is encoded by the TFDP2 gene.

New!!: E2F and TFDP2 · See more »

Thymidine kinase

Thymidine kinase is an enzyme, a phosphotransferase (a kinase): 2'-deoxythymidine kinase, ATP-thymidine 5'-phosphotransferase, EC

New!!: E2F and Thymidine kinase · See more »

Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

New!!: E2F and Transcription factor · See more »

Transcription factor DP

In molecular biology, transcription factor DP (Dimerization Partner) is a family of proteins which function as transcription factors.

New!!: E2F and Transcription factor DP · See more »

Type 3c (Pancreatogenic) Diabetes

Type 3c diabetes (also known as Pancreatogenic diabetes) is a form of diabetes that is being researched.

New!!: E2F and Type 3c (Pancreatogenic) Diabetes · See more »

Winged-helix transcription factors

Consisting of about 110 amino acids, the domain in winged-helix transcription factors (see Regulation of gene expression) has four helices and a two-strand beta-sheet.

New!!: E2F and Winged-helix transcription factors · See more »

X-ray crystallography

X-ray crystallography is a technique used for determining the atomic and molecular structure of a crystal, in which the crystalline atoms cause a beam of incident X-rays to diffract into many specific directions.

New!!: E2F and X-ray crystallography · See more »


[1] https://en.wikipedia.org/wiki/E2F

Hey! We are on Facebook now! »