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ERG (gene)

Index ERG (gene)

ERG (ETS-related gene) is an oncogene. [1]

28 relations: Acute myeloid leukemia, Androgen receptor, Angiogenesis, Apoptosis, C-jun, Cell growth, Cellular differentiation, DNA-binding domain, Embryogenesis, Endothelium, ETS transcription factor family, ETS2, Ewing sarcoma breakpoint region 1, Ewing's sarcoma, FUS (gene), Fusion gene, Haematopoiesis, Inflammation, Lymphocyte, Myelocyte, Oncogene, Philadelphia chromosome, Platelet adhesiveness, Prostate cancer, Protein–protein interaction, Purine, TMPRSS2, White blood cell.

Acute myeloid leukemia

Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells.

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Androgen receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.

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Angiogenesis

Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.

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Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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C-jun

c-Jun is a protein that in humans is encoded by the JUN gene.

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Cell growth

The term cell growth is used in the contexts of biological cell development and cell division (reproduction).

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Cellular differentiation

In developmental biology, cellular differentiation is the process where a cell changes from one cell type to another.

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DNA-binding domain

A DNA-binding domain (DBD) is an independently folded protein domain that contains at least one structural motif that recognizes double- or single-stranded DNA.

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Embryogenesis

Embryogenesis is the process by which the embryo forms and develops.

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Endothelium

Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

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ETS transcription factor family

In the field of molecular biology, the ETS (E26 transformation-specific or E-twenty-six) family is one of the largest families of transcription factors and is unique to animals.

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ETS2

Protein C-ets-2 is a protein that in humans is encoded by the ETS2 gene.

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Ewing sarcoma breakpoint region 1

RNA-binding protein EWS is a protein that in humans is encoded by the EWSR1 gene on human chromosome 22.

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Ewing's sarcoma

Ewing's sarcoma or Ewing sarcoma is a malignant small, round, blue cell tumor.

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FUS (gene)

RNA-binding protein FUS/TLS (Fused in Sarcoma/Translocated in Sarcoma) is a protein that in humans is encoded by the FUS gene.

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Fusion gene

A fusion gene is a hybrid gene formed from two previously separate genes.

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Haematopoiesis

Haematopoiesis (from Greek αἷμα, "blood" and ποιεῖν "to make"; also hematopoiesis in American English; sometimes also haemopoiesis or hemopoiesis) is the formation of blood cellular components.

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Lymphocyte

A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system.

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Myelocyte

A myelocyte is a young cell of the granulocytic series, occurring normally in bone marrow (can be found in circulating blood when caused by certain diseases).

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Oncogene

An oncogene is a gene that has the potential to cause cancer.

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Philadelphia chromosome

The Philadelphia chromosome or Philadelphia translocation (Ph) is a specific genetic abnormality in chromosome 22 of leukemia cancer cells (particularly chronic myeloid leukemia (CML) cells).

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Platelet adhesiveness

Platelet adhesiveness is the adhesion of platelets to other structures.

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Prostate cancer

Prostate cancer is the development of cancer in the prostate, a gland in the male reproductive system.

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Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

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Purine

A purine is a heterocyclic aromatic organic compound that consists of a pyrimidine ring fused to an imidazole ring.

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TMPRSS2

Transmembrane protease, serine 2 is an enzyme that in humans is encoded by the TMPRSS2 gene.

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White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

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Redirects here:

Transcriptional regulator ERG.

References

[1] https://en.wikipedia.org/wiki/ERG_(gene)

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