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Early 35 kDa protein

Index Early 35 kDa protein

The Early 35 kDa protein, or P35 in short, is a baculoviral protein that inhibits apoptosis in the cells infected by the virus. [1]

29 relations: Apoptosis, Autographa californica, Baculoviridae, BASF, Beta sheet, Bombyx mori, Bystander effect (radiobiology), Caspase, Caspase 1, Caspase 10, Caspase 3, Caspase 6, Caspase 7, Caspase 8, Competitive inhibition, Ectopic expression, Gene therapy, Hao Wu (biochemist), Invertebrate, Lois K. Miller, Nuclear Polyhedrosis Virus, Organ transplantation, Sf caspase-1, Thioester, Transplant rejection, University of Georgia, Vertebrate, Weill Cornell Medicine, Worcester, Massachusetts.

Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Autographa californica

The alfalfa looper (Autographa californica) is a moth of the Noctuidae family.

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Baculoviridae

Baculoviridae is a family of viruses.

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BASF

BASF SE is a German chemical company and the largest chemical producer in the world.

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Beta sheet

The β-sheet (also β-pleated sheet) is a common motif of regular secondary structure in proteins.

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Bombyx mori

The silkworm is the larva or caterpillar or imago of the domestic silkmoth, Bombyx mori (Latin: "silkworm of the mulberry tree").

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Bystander effect (radiobiology)

The radiation-induced bystander effect (bystander effect) is the phenomenon in which unirradiated cells exhibit irradiated effects as a result of signals received from nearby irradiated cells.

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Caspase

Caspases (cysteine-aspartic proteases, cysteine aspartases or cysteine-dependent aspartate-directed proteases) are a family of protease enzymes playing essential roles in programmed cell death (including apoptosis, pyroptosis and necroptosis) and inflammation.

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Caspase 1

Caspase-1/Interleukin-1 converting enzyme (ICE) is an evolutionarily conserved enzyme that proteolytically cleaves other proteins, such as the precursors of the inflammatory cytokines interleukin 1β and interleukin 18 as well as the pyroptosis inducer Gasdermin D, into active mature peptides.

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Caspase 10

Caspase-10 is an enzyme that, in humans, is encoded by the CASP10 gene.

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Caspase 3

Caspase-3 is a caspase protein that interacts with caspase-8 and caspase-9.

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Caspase 6

Caspase-6 is an enzyme that in humans is encoded by the CASP6 gene.

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Caspase 7

Caspase-7, apoptosis-related cysteine peptidase, also known as CASP7, is a human protein encoded by the CASP7 gene.

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Caspase 8

Caspase-8 is a caspase protein, encoded by the CASP8 gene.

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Competitive inhibition

Competitive inhibition is a form of enzyme inhibition where binding of an inhibitor prevents binding of the target molecule of the enzyme, also known as the substrate.

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Ectopic expression

Ectopic is a word used with a prefix, ecto, meaning “out of place.” Ectopic expression is an abnormal gene expression in a cell type, tissue type, or developmental stage in which the gene is not usually expressed.

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Gene therapy

In the medicine field, gene therapy (also called human gene transfer) is the therapeutic delivery of nucleic acid into a patient's cells as a drug to treat disease.

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Hao Wu (biochemist)

Hao Wu (吴皓), Ph.D., is a Chinese American biochemist and crystallographer and the Asa and Patricia Springer Professor of Structural Biology in the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School.

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Invertebrate

Invertebrates are animals that neither possess nor develop a vertebral column (commonly known as a backbone or spine), derived from the notochord.

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Lois K. Miller

Lois Kathryn Miller (October 8, 1945Miller's National Academy of Sciences biographical memoir lists two birthdates – this one and May 2, 1945. – November 9, 1999) was an American geneticist and academic.

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Nuclear Polyhedrosis Virus

The nuclear polyhedrosis virus (NPV), part of the family of baculoviruses, is a virus affecting insects, predominantly moths and butterflies.

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Organ transplantation

Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ.

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Sf caspase-1

The protein Sf caspase-1 is the insect ortholog of the human effector caspases CASP3 (CPP32) and CASP7 (MCH3) in the species ''Spodoptera frugiperda'' (Fall armyworm).

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Thioester

In chemistry thioesters are compounds with the functional group R–S–CO–R'.

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Transplant rejection

Transplant rejection occurs when transplanted tissue is rejected by the recipient's immune system, which destroys the transplanted tissue.

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University of Georgia

The University of Georgia, also referred to as UGA or simply Georgia, is an American public comprehensive research university.

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Vertebrate

Vertebrates comprise all species of animals within the subphylum Vertebrata (chordates with backbones).

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Weill Cornell Medicine

Weill Cornell Medicine is the biomedical research unit and medical school of Cornell University, a private Ivy League university.

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Worcester, Massachusetts

Worcester is a city and the county seat of Worcester County, Massachusetts, United States.

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References

[1] https://en.wikipedia.org/wiki/Early_35_kDa_protein

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