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Ecadotril

Index Ecadotril

Ecadotril is a neutral endopeptidase inhibitor ((NEP) EC 3.4.24.11) and determined by the presence of peptidase family M13 as a neutral endopeptidase inhibited by phosphoramidon. [1]

11 relations: Candoxatril, Enantiomer, Endothelin, Endothelin converting enzyme 1, Enkephalinase, Neprilysin, Phosphoramidon, Racecadotril, RB-101, Thermolysin, Thiorphan.

Candoxatril

Candoxatril is the orally active prodrug of candoxatrilat (UK-73967) human neutral endopeptidase (Neprilysin) as the neutral endopeptidase 24.11 complexed (RB-101) with phosphoramidon degrades and inactivates a number of bioactive peptides.

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Enantiomer

In chemistry, an enantiomer, also known as an optical isomer (and archaically termed antipode or optical antipode), is one of two stereoisomers that are mirror images of each other that are non-superposable (not identical), much as one's left and right hands are the same except for being reversed along one axis (the hands cannot be made to appear identical simply by reorientation).

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Endothelin

Endothelins are peptides with receptors and effects in many body organs.

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Endothelin converting enzyme 1

Endothelin converting enzyme 1, also known as ECE1, is an enzyme which in humans is encoded by the ECE1 gene.

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Enkephalinase

Enkephalinases are enzymes that degrade endogenous enkephalin opioid peptides.

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Neprilysin

Neprilysin, also known as membrane metallo-endopeptidase (MME), neutral endopeptidase (NEP), cluster of differentiation 10 (CD10), and common acute lymphoblastic leukemia antigen (CALLA) is an enzyme that in humans is encoded by the MME gene.

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Phosphoramidon

Phosphoramidon is a chemical compound derived from cultures of Streptomyces tanashiensis.

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Racecadotril

Racecadotril, also known as acetorphan, is an antidiarrheal drug which acts as a peripherally acting enkephalinase inhibitor.

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RB-101

RB-101 is a drug that acts as an enkephalinase inhibitor, which is used in scientific research.

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Thermolysin

Thermolysin (Bacillus thermoproteolyticus neutral proteinase, thermoase, thermoase Y10, TLN) is a thermostable neutral metalloproteinase enzyme produced by the Gram-positive bacteria Bacillus thermoproteolyticus.

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Thiorphan

Thiorphan is the active metabolite of the antidiarrheal racecadotril (acetorphan).

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References

[1] https://en.wikipedia.org/wiki/Ecadotril

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