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Triclabendazole

Index Triclabendazole

Triclabendazole, sold under the brand name Egaten among others, is a medication used to treat liver flukes, specifically fascioliasis and paragonimiasis. It is very effective for both conditions. Treatment in hospital may be required. It is taken by mouth with typically one or two doses being required. Side effects are generally few, but can include abdominal pain and headaches. Biliary colic may occur due to dying worms. While no harms have been found with use during pregnancy, triclabendazole has not been well studied in this population. It is a member of the benzimidazole family of medications for worms. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. It is not commercially available in the United States. For human use it can be obtained from the World Health Organization. It is also used in other animals. [1]

15 relations: Anthelmintic, Benzimidazole, Biliary colic, Carbamate, Fasciola hepatica, Fasciolosis, Health system, Ivermectin, Liver fluke, Microtubule, Nematode, Paragonimiasis, Pregnancy, Tubulin, WHO Model List of Essential Medicines.

Anthelmintic

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host.

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Benzimidazole

Benzimidazole is a heterocyclic aromatic organic compound.

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Biliary colic

Biliary colic, also known as a gallbladder attack or gallstone attack, is when pain occurs due to a gallstone temporarily blocking the bile duct.

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Carbamate

A carbamate is an organic compound derived from carbamic acid (NH2COOH).

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Fasciola hepatica

Fasciola hepatica, also known as the common liver fluke or sheep liver fluke, is a parasitic trematode (fluke or flatworm, a type of helminth) of the class Trematoda, phylum Platyhelminthes.

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Fasciolosis

Fasciolosis is a parasitic worm infection caused by the common liver fluke Fasciola hepatica as well as by Fasciola gigantica.

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Health system

A health system, also sometimes referred to as health care system or as healthcare system, is the organization of people, institutions, and resources that deliver health care services to meet the health needs of target populations.

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Ivermectin

Ivermectin is a medication that is effective against many types of parasites.

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Liver fluke

Liver fluke is a collective name of a polyphyletic group of parasitic trematodes under the phylum Platyhelminthes.

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Microtubule

Microtubules are tubular polymers of tubulin that form part of the cytoskeleton that provides the cytoplasm of eukaryotic cells and some bacteria with structure and shape.

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Nematode

The nematodes or roundworms constitute the phylum Nematoda (also called Nemathelminthes).

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Paragonimiasis

Paragonimiasis is a food-borne parasitic infection caused by the lung fluke, most commonly Paragonimus westermani.

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Pregnancy

Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.

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Tubulin

Tubulin in molecular biology can refer either to the tubulin protein superfamily of globular proteins, or one of the member proteins of that superfamily.

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WHO Model List of Essential Medicines

The WHO Model List of Essential Medicines (EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.

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Redirects here:

ATC code P02BX04, ATCvet code QP52AC01, C14H9Cl3N2OS, Egaten, Fasinex.

References

[1] https://en.wikipedia.org/wiki/Triclabendazole

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