116 relations: Adult stem cell, Amniocentesis, Astellas Institute for Regenerative Medicine, Atlanta, Barack Obama, BBC, Beta cell, BioTime, Blastocyst, Bone marrow, Bone morphogenetic protein, Cambridge, Cardiac muscle cell, Cell biology, Cell growth, Cell potency, Cellular differentiation, Chromosome abnormality, Cystic fibrosis, Diabetes mellitus, Ectoderm, EMBO Reports, Embryo, Embryoid body, Embryonic, Embryonic Stem Cell Research Oversight Committees, Endoderm, Endothelium, European Heart Journal, Fetal tissue implant, Fibroblast, Flow cytometry, Food and Drug Administration, Fragile X syndrome, Gail R. Martin, Gastrulation, Genetic disorder, Genetics, George W. Bush, Germ cell, Germ cell tumor, Germ layer, Geron Corporation, Harvard University, Hepatocyte, HIV/AIDS, Homology directed repair, Human fertilization, Immortalised cell line, Implantation (human embryo), ..., Induced pluripotent stem cell, Induced stem cells, Inner cell mass, Islet, Japan, John Gurdon, Karyotype, Knockout mouse, Kyoto, Leukemia inhibitory factor, List of distinct cell types in the adult human body, Macular degeneration, Martin Evans, Massachusetts, Matthew Kaufman, Medical research, Menlo Park, California, Mesoderm, Michael D. West, Microsurgery, Mitomycins, Mitosis, National Institutes of Health, Natural killer cell, Nature (journal), Nature Publishing Group, Neurodegeneration, Neuron, Non-homologous end joining, Oligodendrocyte, Ovary, Parkinson's disease, Phenotype, Precursor cell, Prenatal testing, Proceedings of the National Academy of Sciences of the United States of America, Progesterone, Reuters, Robert Lanza, Rudolf Jaenisch, Science (journal), Shepherd Center, Shinya Yamanaka, Sialic acid, Sickle cell disease, Spinal cord injury, Spinal cord injury research, Stem cell, Stem cell controversy, Stem cell research policy, Stem-cell therapy, Telomerase, Teratoma, The Guardian, The Washington Post, Toxicology, Transcription factor, Transgene, University of California, Irvine, University of California, San Diego, University of California, San Francisco, University of Cambridge, University of Wisconsin–Madison, USA Today, Whitehead Institute, Yury Verlinsky. Expand index (66 more) » « Shrink index
Adult stem cells are undifferentiated cells, found throughout the body after development, that multiply by cell division to replenish dying cells and regenerate damaged tissues.
Amniocentesis (also referred to as amniotic fluid test or AFT) is a medical procedure used in prenatal diagnosis of chromosomal abnormalities and fetal infections, and also for sex determination, in which a small amount of amniotic fluid, which contains fetal tissues, is sampled from the amniotic sac surrounding a developing fetus, and then the fetal DNA is examined for genetic abnormalities.
Astellas Institute for Regenerative Medicine is a subsidiary of Astellas Pharma located in Marlborough, Massachusetts, developing stem cell therapies with a focus on diseases that cause blindness.
Atlanta is the capital city and most populous municipality of the state of Georgia in the United States.
Barack Hussein Obama II (born August 4, 1961) is an American politician who served as the 44th President of the United States from January 20, 2009, to January 20, 2017.
The British Broadcasting Corporation (BBC) is a British public service broadcaster.
Beta cells (β cells) are a type of cell found in the pancreatic islets of the pancreas.
The blastocyst is a structure formed in the early development of mammals.
Bone marrow is a semi-solid tissue which may be found within the spongy or cancellous portions of bones.
Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens.
Cambridge is a university city and the county town of Cambridgeshire, England, on the River Cam approximately north of London.
Cardiac muscle cells or cardiomyocytes (also known as myocardiocytes or cardiac myocytes) are the muscle cells (myocytes) that make up the cardiac muscle (heart muscle).
Cell biology (also called cytology, from the Greek κυτος, kytos, "vessel") is a branch of biology that studies the structure and function of the cell, the basic unit of life.
The term cell growth is used in the contexts of biological cell development and cell division (reproduction).
Cell potency is a cell's ability to differentiate into other cell types The more cell types a cell can differentiate into, the greater its potency.
In developmental biology, cellular differentiation is the process where a cell changes from one cell type to another.
A chromosome abnormality, disorder, anomaly, aberration, or mutation is a missing, extra, or irregular portion of chromosomal DNA.
Cystic fibrosis (CF) is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine.
Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.
Ectoderm is one of the three primary germ layers in the very early embryo.
EMBO Reports is a peer-reviewed scientific journal covering research related to biology at a molecular level.
An embryo is an early stage of development of a multicellular diploid eukaryotic organism.
Embryoid bodies (EBs) are three-dimensional aggregates of pluripotent stem cells.
Embryonic is the twelfth studio album by experimental rock band The Flaming Lips released on October 13, 2009 on Warner Bros.
The National Academies called for the establishment of Embryonic Stem Cell Research Oversight (ESCRO) Committees in its 2005 Guidelines for Human Embryonic Stem Cell Research to manage the ethical and legal concerns in human embryonic stem cell research.
Endoderm is one of the three primary germ layers in the very early embryo.
Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.
The European Heart Journal is a leading peer-reviewed medical journal of cardiology published by Oxford University Press on a weekly basis, on behalf of the European Society of Cardiology.
Fetal tissue implant or fetal cell therapy is an experimental medical therapy where researchers implant tissue from a fetus into a person as treatment of a disease.
A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing.
In biotechnology, flow cytometry is a laser- or impedance-based, biophysical technology employed in cell counting, cell sorting, biomarker detection and protein engineering, by suspending cells in a stream of fluid and passing them through an electronic detection apparatus.
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
Fragile X syndrome (FXS) is a genetic disorder.
Gail Roberta Martin (née Zuckman) is a professor emerita in the Department of Anatomy, University of California, San Francisco.
Gastrulation is a phase early in the embryonic development of most animals, during which the single-layered blastula is reorganized into a multilayered structure known as the gastrula.
A genetic disorder is a genetic problem caused by one or more abnormalities in the genome.
Genetics is the study of genes, genetic variation, and heredity in living organisms.
George Walker Bush (born July 6, 1946) is an American politician who served as the 43rd President of the United States from 2001 to 2009.
A germ cell is any biological cell that gives rise to the gametes of an organism that reproduces sexually.
A germ cell tumor (GCT) is a neoplasm derived from germ cells.
A germ layer is a primary layer of cells that form during embryogenesis.
Geron Corporation is a biotechnology company located in Menlo Park, California, which specializes in developing and commercializing therapeutic products for cancer that inhibit telomerase.
Harvard University is a private Ivy League research university in Cambridge, Massachusetts.
A hepatocyte is a cell of the main parenchymal tissue of the liver.
Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV).
Homology directed repair (HDR) is a mechanism in cells to repair double strand DNA lesions.
Human fertilization is the union of a human egg and sperm, usually occurring in the ampulla of the fallopian tube.
An immortalized cell line is a population of cells from a multicellular organism which would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division.
In humans, implantation is the stage of pregnancy at which the already fertilized egg adheres to the wall of the uterus.
Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from adult cells.
Induced stem cells (iSC) are stem cells derived from somatic, reproductive, pluripotent or other cell types by deliberate epigenetic reprogramming.
In early embryogenesis of most eutherian mammals, the inner cell mass (abbreviated ICM and also known as the embryoblast in mammals or pluriblast) is the mass of cells inside the primordial embryo that will eventually give rise to the definitive structures of the fetus.
An islet is a very small island.
Japan (日本; Nippon or Nihon; formally 日本国 or Nihon-koku, lit. "State of Japan") is a sovereign island country in East Asia.
Sir John Bertrand Gurdon (born 2 October 1933), is an English developmental biologist.
A karyotype is the number and appearance of chromosomes in the nucleus of a eukaryotic cell.
A knockout mouse or knock-out mouse is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA.
, officially, is the capital city of Kyoto Prefecture, located in the Kansai region of Japan.
Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation.
There are many different types of cell in the human body.
Macular degeneration, also known as age-related macular degeneration (AMD or ARMD), is a medical condition which may result in blurred or no vision in the center of the visual field.
Sir Martin John Evans (born 1 January 1941) is a British biologist who, with Matthew Kaufman, was the first to culture mice embryonic stem cells and cultivate them in a laboratory in 1981.
Massachusetts, officially known as the Commonwealth of Massachusetts, is the most populous state in the New England region of the northeastern United States.
Matthew H. Kaufman (29 September 1942 – 11 August 2013) was Professor Emeritus at University of Edinburgh having been Professor of Anatomy there from 1985 to 2007.
Biomedical research (or experimental medicine) encompasses a wide array of research, extending from "basic research" (also called bench science or bench research), – involving fundamental scientific principles that may apply to a ''preclinical'' understanding – to clinical research, which involves studies of people who may be subjects in clinical trials.
Menlo Park is a city at the eastern edge of San Mateo County, in the San Francisco Bay Area of California, in the United States.
In all bilaterian animals, the mesoderm is one of the three primary germ layers in the very early embryo.
Michael D. West is a gerontologist, and a pioneer in stem cells, cellular aging and telomerase.
Microsurgery is a general term for surgery requiring an operating microscope.
The mitomycins are a family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae. They include mitomycin A, mitomycin B, and mitomycin C. When the name mitomycin occurs alone, it usually refers to mitomycin C, its international nonproprietary name.
In cell biology, mitosis is a part of the cell cycle when replicated chromosomes are separated into two new nuclei.
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.
Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system.
Nature is a British multidisciplinary scientific journal, first published on 4 November 1869.
Nature Publishing Group is a division of the international scientific publishing company Springer Nature that publishes academic journals, magazines, online databases, and services in science and medicine.
Neurodegeneration is the progressive loss of structure or function of neurons, including death of neurons.
A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.
Non-homologous end joining (NHEJ) is a pathway that repairs double-strand breaks in DNA.
Oligodendrocytes, or oligodendroglia,.
The ovary is an organ found in the female reproductive system that produces an ovum.
Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system.
A phenotype is the composite of an organism's observable characteristics or traits, such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior (such as a bird's nest).
In cell biology, a precursor cell, also called a blast cell or simply blast, is a partially differentiated cell, usually referred to as a unipotent cell that has lost most of its stem cell properties.
Prenatal testing consists of prenatal screening and prenatal diagnosis, which are aspects of prenatal care that focus on detecting problems with the pregnancy as early as possible.
Proceedings of the National Academy of Sciences of the United States of America (PNAS) is the official scientific journal of the National Academy of Sciences, published since 1915.
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.
Reuters is an international news agency headquartered in London, United Kingdom.
Robert Lanza (born 11 February 1956) is an American medical doctor and scientist.
Rudolf Jaenisch (born 22 April 1942) is a Professor of Biology at MIT and a founding member of the Whitehead Institute for Biomedical Research.
Science, also widely referred to as Science Magazine, is the peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals.
Shepherd Center is a private, not-for profit hospital in Atlanta, Georgia.
is a Japanese Nobel Prize-winning stem cell researcher.
Sialic acid is a generic term for the N- or O-substituted derivatives of neuraminic acid, a monosaccharide with a nine-carbon backbone.
Sickle cell disease (SCD) is a group of blood disorders typically inherited from a person's parents.
A spinal cord injury (SCI) is damage to the spinal cord that causes temporary or permanent changes in its function.
Spinal cord injury research seeks new ways to cure or treat spinal cord injury in order to lessen the debilitating effects of the injury in the short or long term.
Stem cells are biological cells that can differentiate into other types of cells and can divide to produce more of the same type of stem cells.
The stem cell controversy is the consideration of the ethics of research involving the development, use, and destruction of human embryos.
Stem cell research policy varies significantly throughout the world.
Stem-cell therapy is the use of stem cells to treat or prevent a disease or condition.
Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres.
A teratoma is a tumor made up of several different types of tissue, such as hair, muscle, or bone.
The Guardian is a British daily newspaper.
The Washington Post is a major American daily newspaper founded on December 6, 1877.
Toxicology is a discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating exposures to toxins and toxicants.
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.
A transgene is a gene or genetic material that has been transferred naturally, or by any of a number of genetic engineering techniques from one organism to another.
The University of California, Irvine (UCI, UC Irvine, or Irvine), is a public research university located in Irvine, Orange County, California, United States, and one of the 10 campuses in the University of California (UC) system.
The University of California, San Diego is a public research university located in the La Jolla neighborhood of San Diego, California, in the United States.
The University of California, San Francisco (UCSF), is a research university located in San Francisco, California and part of the University of California system.
The University of Cambridge (informally Cambridge University)The corporate title of the university is The Chancellor, Masters, and Scholars of the University of Cambridge.
The University of Wisconsin–Madison (also known as University of Wisconsin, Wisconsin, UW, or regionally as UW–Madison, or simply Madison) is a public research university in Madison, Wisconsin, United States.
USA Today is an internationally distributed American daily, middle-market newspaper that serves as the flagship publication of its owner, the Gannett Company.
Founded in 1982, the Whitehead Institute for Biomedical Research is a non-profit research and teaching institution located in Cambridge, Massachusetts, United States.
Yury Verlinsky (1 September 1943 – 16 July 2009) was a Russian-American medical researcher specializing in embryo and cellular genetics (genetic cytology).
Blastocyst stem cell, ES cell, ES cells, Embryonic Stem Cell, Embryonic Stem Cell Therapy, Embryonic Stem Cells, Embryonic stem (es) cells, Embryonic stem cell research, Embryonic stem cells, Embryonic stem-cell, Embryonic stem-cell research, Embyronic stem cells, HESC, Human embryonic stem cell, Human embryonic stem cells.