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22 relations: Apoptosis, Asthma, Atopic dermatitis, Bronchus, Cutaneous condition, Eosinophil, Eosinophil-derived neurotoxin, Erythema, Gene, Glycosylation, Granule (cell biology), Helminths, Immunoglobulin E, Itch, Necrosis, Neurotoxicity, Pancreatic ribonuclease, Papule, Reference ranges for blood tests, Ribonuclease, RNA, Sleep deprivation.
Apoptosis
Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.
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Asthma
Asthma is a common long-term inflammatory disease of the airways of the lungs.
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Atopic dermatitis
Atopic dermatitis (AD), also known as atopic eczema, is a type of inflammation of the skin (dermatitis).
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Bronchus
A bronchus, is a passage of airway in the respiratory system that conducts air into the lungs.
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Cutaneous condition
A cutaneous condition is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, hair, nails, and related muscle and glands.
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Eosinophil
Eosinophils sometimes called eosinophiles or, less commonly, acidophils, are a variety of white blood cells and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates. Along with mast cells and basophils, they also control mechanisms associated with allergy and asthma. They are granulocytes that develop during hematopoiesis in the bone marrow before migrating into blood, after which they are terminally differentiated and do not multiply. These cells are eosinophilic or "acid-loving" due to their large acidophilic cytoplasmic granules, which show their affinity for acids by their affinity to coal tar dyes: Normally transparent, it is this affinity that causes them to appear brick-red after staining with eosin, a red dye, using the Romanowsky method. The staining is concentrated in small granules within the cellular cytoplasm, which contain many chemical mediators, such as eosinophil peroxidase, ribonuclease (RNase), deoxyribonucleases (DNase), lipase, plasminogen, and major basic protein. These mediators are released by a process called degranulation following activation of the eosinophil, and are toxic to both parasite and host tissues. In normal individuals, eosinophils make up about 1–3% of white blood cells, and are about 12–17 micrometres in size with bilobed nuclei. While they are released into the bloodstream as neutrophils are, eosinophils reside in tissue They are found in the medulla and the junction between the cortex and medulla of the thymus, and, in the lower gastrointestinal tract, ovary, uterus, spleen, and lymph nodes, but not in the lung, skin, esophagus, or some other internal organs under normal conditions. The presence of eosinophils in these latter organs is associated with disease. For instance, patients with eosinophilic asthma have high levels of eosinophils that lead to inflammation and tissue damage, making it more difficult for patients to breathe. Eosinophils persist in the circulation for 8–12 hours, and can survive in tissue for an additional 8–12 days in the absence of stimulation. Pioneering work in the 1980s elucidated that eosinophils were unique granulocytes, having the capacity to survive for extended periods of time after their maturation as demonstrated by ex-vivo culture experiments.
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Eosinophil-derived neurotoxin
Eosinophil-derived neurotoxin is an enzyme that in humans is encoded by the RNASE2 gene.
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Erythema
Erythema (from the Greek erythros, meaning red) is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Glycosylation
Glycosylation (see also chemical glycosylation) is the reaction in which a carbohydrate, i.e. a glycosyl donor, is attached to a hydroxyl or other functional group of another molecule (a glycosyl acceptor).
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Granule (cell biology)
In cell biology, a granule is a small particle.
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Helminths
Helminths, also commonly known as parasitic worms, are large multicellular parasites, which can generally be seen with the naked eye when they are mature.
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Immunoglobulin E
Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals.
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Itch
Itch (also known as pruritus) is a sensation that causes the desire or reflex to scratch.
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Necrosis
Necrosis (from the Greek νέκρωσις "death, the stage of dying, the act of killing" from νεκρός "dead") is a form of cell injury which results in the premature death of cells in living tissue by autolysis.
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Neurotoxicity
Neurotoxicity is a form of toxicity in which a biological, chemical, or physical agent produces an adverse effect on the structure or function of the central and/or peripheral nervous system.
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Pancreatic ribonuclease
Pancreatic ribonucleases (RNase, RNase I, RNase A, pancreatic RNase, ribonuclease I, endoribonuclease I, ribonucleic phosphatase, alkaline ribonuclease, ribonuclease, gene S glycoproteins, Ceratitis capitata alkaline ribonuclease, SLSG glycoproteins, gene S locus-specific glycoproteins, S-genotype-assocd. glycoproteins, ribonucleate 3'-pyrimidino-oligonucleotidohydrolase) are pyrimidine-specific endonucleases found in high quantity in the pancreas of certain mammals and of some reptiles.
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Papule
A papule is a circumscribed, solid elevation of skin with no visible fluid, varying in area from a pinhead to 1 cm.
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Reference ranges for blood tests
Reference ranges for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples.
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Ribonuclease
Ribonuclease (commonly abbreviated RNase) is a type of nuclease that catalyzes the degradation of RNA into smaller components.
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RNA
Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.
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Sleep deprivation
Sleep deprivation is the condition of not having enough sleep; it can be either chronic or acute.
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References
[1] https://en.wikipedia.org/wiki/Eosinophil_cationic_protein
