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20 relations: Androstane, Androstanedione, Androsterone, Epiandrosterone, Etiocholane, Etiocholanolone, Excretion, Glucuronidation, Liver, Metabolic pathway, Metabolite, Steroid, Sulfation, Testosterone, Urine, 17β-Hydroxysteroid dehydrogenase, 3β,5β-Androstanediol, 3β-Hydroxysteroid dehydrogenase, 5β-Dihydrotestosterone, 5β-Reductase.
Androstane
Androstane is a C19 steroid with a gonane core.
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Androstanedione
Androstanediones are a pair of isomeric steroids which differ at the 5-position.
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Androsterone
Androsterone, or 5α-androstan-3α-ol-17-one, is an endogenous steroid hormone, neurosteroid, and putative pheromone.
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Epiandrosterone
Epiandrosterone, or isoandrosterone, also known as 3β-androsterone, 3β-hydroxy-5α-androstan-17-one, or 5α-androstan-3β-ol-17-one, is a steroid hormone with weak androgenic activity.
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Etiocholane
Etiocholane, also known as 5β-androstane or 5-epiandrostane, is an androstane (C19) steroid.
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Etiocholanolone
Etiocholanolone, also known as 5β-androsterone, as well as 3α-hydroxy-5β-androstan-17-one or etiocholan-3α-ol-17-one, is an etiocholane (5β-androstane) steroid as well as an endogenous 17-ketosteroid that is produced from the metabolism of testosterone.
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Excretion
Excretion is the process by which metabolic waste is eliminated from an organism.
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Glucuronidation
Glucuronidation is often involved in drug metabolism of substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Metabolic pathway
In biochemistry, a metabolic pathway is a linked series of chemical reactions occurring within a cell.
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Metabolite
A metabolite is the intermediate end product of metabolism.
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Steroid
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
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Sulfation
Sulfation or sulfurylation (not to be confused with sulfonation) in biochemistry is the enzyme-catalyzed conjugation of a sulfo group (not a sulfate or sulfuryl group) to another molecule.
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Testosterone
Testosterone is the primary male sex hormone and an anabolic steroid.
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Urine
Urine is a liquid by-product of metabolism in humans and in many animals.
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17β-Hydroxysteroid dehydrogenase
17β-Hydroxysteroid dehydrogenases (17β-HSD, HSD17B), also 17-ketosteroid reductases (17-KSR), are a group of alcohol oxidoreductases which catalyze the reduction of 17-ketosteroids and the dehydrogenation of 17β-hydroxysteroids in steroidogenesis and steroid metabolism.
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3β,5β-Androstanediol
3β,5β-Androstanediol, also known as epietiocholanediol, as well as 5β-androstane-3β,17β-diol or etiocholane-3β,17β-diol, is an endogenous, naturally occurring steroid that is formed as a metabolite of testosterone.
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3β-Hydroxysteroid dehydrogenase
3β-Hydroxysteroid dehydrogenase/Δ5-4 isomerase (3β-HSD) is an enzyme that catalyzes the biosynthesis of progesterone from pregnenolone, 17α-hydroxyprogesterone from 17α-hydroxypregnenolone, and androstenedione from dehydroepiandrosterone (DHEA) in the adrenal gland.
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5β-Dihydrotestosterone
5β-Dihydrotestosterone (5β-DHT), also known as 5β-androstan-17β-ol-3-one or as etiocholan-17β-ol-3-one, is an etiocholane (5β-androstane) steroid as well as an inactive metabolite of testosterone formed by 5β-reductase in the liver and bone marrow and an intermediate in the formation of 3α,5β-androstanediol and 3β,5β-androstanediol (by 3α- and 3β-hydroxysteroid dehydrogenase) and, from them, respectively, etiocholanolone and epietiocholanolone (by 17β-hydroxysteroid dehydrogenase).
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5β-Reductase
5β-Reductase, or Δ4-3-oxosteroid 5β-reductase (3-oxo-Δ4-steroid 5β-reductase, androstenedione 5β-reductase, cholestenone 5β-reductase, cortisone 5β-reductase, cortisone Δ4-5β-reductase, steroid 5β-reductase, testosterone 5β-reductase, Δ4-3-ketosteroid 5β-reductase, Δ4-5β-reductase, Δ4-hydrogenase, 4,5β-dihydrocortisone:NADP+ Δ4-oxidoreductase, 3-oxo-5β-steroid:NADP+ Δ4-oxidoreductase) is an enzyme with systematic name 5β-cholestan-3-one:NADP+ 4,5-oxidoreductase.
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