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Epostane

Index Epostane

Epostane (INN, USAN, BAN) (developmental code name WIN-32729) is an inhibitor of 3β-hydroxysteroid dehydrogenase (3β-HSD) that was developed as a contraceptive, abortifacient, and oxytocic drug but was never marketed. [1]

Table of Contents

  1. 20 relations: Abortifacient, Androstenedione, Antiprogestogen, Biosynthesis, Birth control, British Approved Name, Dehydroepiandrosterone, Drug, Enzyme inhibitor, International nonproprietary name, Medical abortion, Mifepristone, Nisterime, Pregnancy, Pregnenolone, Progesterone, Trilostane, United States Adopted Name, Uterotonic, 3β-Hydroxysteroid dehydrogenase.

  2. 1-Methylcyclopentanols
  3. 3β-Hydroxysteroid dehydrogenase inhibitors
  4. Antiprogestogens
  5. Cyclohexenols
  6. Enols

Abortifacient

An abortifacient ("that which will cause a miscarriage" from Latin: abortus "miscarriage" and faciens "making") is a substance that induces abortion.

See Epostane and Abortifacient

Androstenedione

Androstenedione, or 4-androstenedione (abbreviated as A4 or Δ4-dione), also known as androst-4-ene-3,17-dione, is an endogenous weak androgen steroid hormone and intermediate in the biosynthesis of estrone and of testosterone from dehydroepiandrosterone (DHEA). Epostane and Androstenedione are Androstanes.

See Epostane and Androstenedione

Antiprogestogen

Antiprogestogens, or antiprogestins, also known as progesterone antagonists or progesterone blockers, are a class of drugs which prevent progestogens like progesterone from mediating their biological effects in the body. Epostane and Antiprogestogen are Antiprogestogens.

See Epostane and Antiprogestogen

Biosynthesis

Biosynthesis, i.e., chemical synthesis occuring in biological contexts, is a term most often referring to multi-step, enzyme-catalyzed processes where chemical substances absorbed as nutrients (or previously converted through biosynthesis) serve as enzyme substrates, with conversion by the living organism either into simpler or more complex products.

See Epostane and Biosynthesis

Birth control

Birth control, also known as contraception, anticonception, and fertility control, is the use of methods or devices to prevent unintended pregnancy.

See Epostane and Birth control

British Approved Name

A British Approved Name (BAN) is the official, non-proprietary, or generic name given to a pharmaceutical substance, as defined in the British Pharmacopoeia (BP).

See Epostane and British Approved Name

Dehydroepiandrosterone

Dehydroepiandrosterone (DHEA), also known as androstenolone, is an endogenous steroid hormone precursor. Epostane and Dehydroepiandrosterone are Androstanes.

See Epostane and Dehydroepiandrosterone

Drug

A drug is any chemical substance other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect.

See Epostane and Drug

Enzyme inhibitor

An enzyme inhibitor is a molecule that binds to an enzyme and blocks its activity.

See Epostane and Enzyme inhibitor

International nonproprietary name

An international nonproprietary name (INN) is an official generic and nonproprietary name given to a pharmaceutical drug or an active ingredient.

See Epostane and International nonproprietary name

Medical abortion

A medical abortion, also known as medication abortion or non-surgical abortion, occurs when drugs (medication) are used to bring about an abortion.

See Epostane and Medical abortion

Mifepristone

Mifepristone, also known as RU-486, is a medication typically used in combination with misoprostol to bring about a medical abortion during pregnancy and manage early miscarriage. Epostane and Mifepristone are Antiprogestogens.

See Epostane and Mifepristone

Nisterime

Nisterime, also known as 2α-chloro-4,5α-dihydrotestosterone 3-O-(p-nitrophenyl)oxime or as 2α-chloro-5α-androstan-17β-ol-3-one 3-O-(p-nitrophenyl)oxime, is a synthetic anabolic-androgenic steroid (AAS) and a derivative of dihydrotestosterone (DHT) that was never marketed. Epostane and Nisterime are Androstanes and steroid stubs.

See Epostane and Nisterime

Pregnancy

Pregnancy is the time during which one or more offspring develops (gestates) inside a woman's uterus (womb).

See Epostane and Pregnancy

Pregnenolone

Pregnenolone (P5), or pregn-5-en-3β-ol-20-one, is an endogenous steroid and precursor/metabolic intermediate in the biosynthesis of most of the steroid hormones, including the progestogens, androgens, estrogens, glucocorticoids, and mineralocorticoids. Epostane and Pregnenolone are Sterols.

See Epostane and Pregnenolone

Progesterone

Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.

See Epostane and Progesterone

Trilostane

Trilostane, sold under the brand name Vetoryl among others, is a medication which has been used in the treatment of Cushing's syndrome, Conn's syndrome, and postmenopausal breast cancer in humans. Epostane and Trilostane are 3β-Hydroxysteroid dehydrogenase inhibitors, Androstanes and Nitriles.

See Epostane and Trilostane

United States Adopted Name

A United States Adopted Name (USAN) is a unique nonproprietary name assigned to a medication marketed in the United States.

See Epostane and United States Adopted Name

Uterotonic

A uterotonic, also known as an oxytocic or ecbolic, is a type of medication used to induce contraction or greater tonicity of the uterus.

See Epostane and Uterotonic

3β-Hydroxysteroid dehydrogenase

3β-Hydroxysteroid dehydrogenase/Δ5-4 isomerase (3β-HSD) is an enzyme that catalyzes the biosynthesis of the steroid progesterone from pregnenolone, 17α-hydroxyprogesterone from 17α-hydroxypregnenolone, and androstenedione from dehydroepiandrosterone (DHEA) in the adrenal gland.

See Epostane and 3β-Hydroxysteroid dehydrogenase

See also

1-Methylcyclopentanols

3β-Hydroxysteroid dehydrogenase inhibitors

Antiprogestogens

Cyclohexenols

Enols

References

[1] https://en.wikipedia.org/wiki/Epostane