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Ergoline

Index Ergoline

Ergoline derivatives comprise a diverse group of chemical compounds whose structural skeleton is the alkaloid ergoline. [1]

78 relations: Agroclavine, Alanine, Albert Hofmann, Alkaloid, Amide, Argyreia nervosa, Arthur Stoll, Benzyl group, Beta-Ergocryptine, Breast milk, Bromine, Bromocriptine, Cabergoline, Caffeine, CAS Registry Number, Chemical compound, Chemical structure, Chemical synthesis, Chemistry, Chirality (chemistry), Convolvulaceae, Cyclol, Dihydroergotamine, Elymoclavine, Epiphyte, Ergine, Ergocornine, Ergocristine, Ergocryptine, Ergoloid, Ergometrine, Ergosine, Ergot, Ergotamine, Ergotism, Ergovaline, Ethyl group, Festuclavine, Flowering plant, Fumigaclavine A, Fumigaclavine B, Fumigaclavine C, Fungus, Hawaii, International nonproprietary name, Ipomoea asarifolia, Ipomoea tricolor, Isoleucine, Lactam, Leucine, ..., Lisuride, Lysergic acid, Lysergic acid diethylamide, Lysergic acid hydroxyethylamide, Lysergol, Methyl group, Methylergometrine, Methysergide, Mexico, Migraine, Parkinson's disease, Peptide, Pergolide, Phenylalanine, Preferred IUPAC name, Proline, Propyl group, Psychedelic drug, Psychoactive drug, Semisynthesis, Structural formula, Toxicity, Turbina corymbosa, United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances, Uterotonic, Valine, Vasoconstriction, 5-HT1 receptor. Expand index (28 more) »

Agroclavine

Agroclavine belongs to the group of ergot alkaloids, such as ergotamine.

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Alanine

Alanine (symbol Ala or A) is an α-amino acid that is used in the biosynthesis of proteins.

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Albert Hofmann

Albert Hofmann (11 January 1906 – 29 April 2008) was a Swiss scientist known best for being the first person to synthesize, ingest, and learn of the psychedelic effects of lysergic acid diethylamide (LSD).

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Alkaloid

Alkaloids are a class of naturally occurring chemical compounds that mostly contain basic nitrogen atoms.

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Amide

An amide (or or), also known as an acid amide, is a compound with the functional group RnE(O)xNR′2 (R and R′ refer to H or organic groups).

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Argyreia nervosa

Argyreia nervosa is a perennial climbing vine native to the Indian subcontinent and introduced to numerous areas worldwide, including Hawaii, Africa, and the Caribbean.

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Arthur Stoll

Arthur Stoll (8 January 1887 – 13 January 1971) was a Swiss biochemist.

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Benzyl group

In organic chemistry, benzyl is the substituent or molecular fragment possessing the structure C6H5CH2–.

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Beta-Ergocryptine

beta-Ergocryptine (β-ergocryptine) is an ergoline alkaloid.

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Breast milk

Breast milk is the milk produced by the breasts (or mammary glands) of a human female to feed a child.

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Bromine

Bromine is a chemical element with symbol Br and atomic number 35.

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Bromocriptine

Bromocriptine (originally marketed as Parlodel, subsequently under many names) is an ergoline derivative, is a dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.

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Cabergoline

Cabergoline (brand names Dostinex and others), an ergot derivative, is a potent dopamine receptor agonist on D2 receptors.

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Caffeine

Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class.

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CAS Registry Number

A CAS Registry Number, also referred to as CASRN or CAS Number, is a unique numerical identifier assigned by the Chemical Abstracts Service (CAS) to every chemical substance described in the open scientific literature (currently including all substances described from 1957 through the present, plus some substances from the early or mid 1900s), including organic and inorganic compounds, minerals, isotopes, alloys and nonstructurable materials (UVCBs, of unknown, variable composition, or biological origin).

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Chemical compound

A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) composed of atoms from more than one element held together by chemical bonds.

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Chemical structure

A chemical structure determination includes a chemist's specifying the molecular geometry and, when feasible and necessary, the electronic structure of the target molecule or other solid.

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Chemical synthesis

Chemical synthesis is a purposeful execution of chemical reactions to obtain a product, or several products.

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Chemistry

Chemistry is the scientific discipline involved with compounds composed of atoms, i.e. elements, and molecules, i.e. combinations of atoms: their composition, structure, properties, behavior and the changes they undergo during a reaction with other compounds.

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Chirality (chemistry)

Chirality is a geometric property of some molecules and ions.

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Convolvulaceae

Convolvulaceae, known commonly as the bindweed or morning glory family, is a family of about 60 genera and more than 1,650 species of mostly herbaceous vines, but also trees, shrubs and herbs.

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Cyclol

The cyclol hypothesis is the first structural model of a folded, globular protein.

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Dihydroergotamine

Dihydroergotamine (DHE) is an ergot alkaloid used to treat migraines.

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Elymoclavine

Elymoclavine is an ergot alkaloid (ergoline alkaloid).

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Epiphyte

An epiphyte is an organism that grows on the surface of a plant and derives its moisture and nutrients from the air, rain, water (in marine environments) or from debris accumulating around it.

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Ergine

Ergine, also known as d-lysergic acid amide (LSA) and d-lysergamide, is an alkaloid of the ergoline family that occurs in various species of vines of the Convolvulaceae and some species of fungi.

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Ergocornine

Ergocornine or 12′-Hydroxy-2′,5′-α-bis(1-methyl-ethyl)ergotaman-3′,6′,18-trione or C31H39N5O5 is a crystalline ergopeptine and one of the ergot alkaloids separated from ergotoxine.

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Ergocristine

Ergocristine is an ergopeptine and one of the ergot alkaloids.

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Ergocryptine

Ergocryptine is an ergopeptine and one of the ergot alkaloids.

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Ergoloid

Ergoloid mesylates (USAN), co-dergocrine mesilate (BAN) or dihydroergotoxine mesylate, trade name Hydergine, is a mixture of the methanesulfonate salts of three dihydrogenated ergot alkaloids (dihydroergocristine, dihydroergocornine, and alpha- and beta-dihydroergocryptine).

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Ergometrine

Ergometrine also known as ergonovine, is a medication used to cause contractions of the uterus to treat heavy vaginal bleeding after childbirth.

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Ergosine

alpha and beta ergosine Ergosines are ergoloid-like chemicals made by Claviceps purpurea.

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Ergot

Ergot (pron.) or ergot fungi refers to a group of fungi of the genus Claviceps.

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Ergotamine

Ergotamine is an ergopeptine and part of the ergot family of alkaloids; it is structurally and biochemically closely related to ergoline.

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Ergotism

Ergotism (pron.) is the effect of long-term ergot poisoning, traditionally due to the ingestion of the alkaloids produced by the Claviceps purpurea fungus that infects rye and other cereals, and more recently by the action of a number of ergoline-based drugs.

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Ergovaline

Ergovaline is an ergopeptine and one of the ergot alkaloids.

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Ethyl group

In chemistry, an ethyl group is an alkyl substituent derived from ethane (C2H6).

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Festuclavine

Festuclavine is an ergoline fungal isolate.

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Flowering plant

The flowering plants, also known as angiosperms, Angiospermae or Magnoliophyta, are the most diverse group of land plants, with 416 families, approximately 13,164 known genera and c. 295,383 known species.

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Fumigaclavine A

Fumigaclavine A is an antibacterial ergoline alkaloid produced by endophytic Aspergillus.

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Fumigaclavine B

Fumigaclavine B is a ergoline compound made by certain fungi.

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Fumigaclavine C

Fumigaclavine C is a ergoline alkaloid produced by Aspergillus fumigatus.

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Fungus

A fungus (plural: fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms.

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Hawaii

Hawaii (Hawaii) is the 50th and most recent state to have joined the United States, having received statehood on August 21, 1959.

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International nonproprietary name

The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.

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Ipomoea asarifolia

Ipomoea asarifolia, the ginger-leaf morning-glory, is a species of plant in the Convolvulaceae family, of the genus Ipomoea.

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Ipomoea tricolor

Ipomoea tricolor, the Mexican morning glory or just morning glory, is a species of flowering plant in the family Convolvulaceae, native to the New World tropics, and widely cultivated and naturalised elsewhere.

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Isoleucine

Isoleucine (symbol Ile or I) is an α-amino acid that is used in the biosynthesis of proteins.

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Lactam

A lactam is a cyclic amide.

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Leucine

Leucine (symbol Leu or L) is an essential amino acid that is used in the biosynthesis of proteins.

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Lisuride

Lisuride, sold under the brand names Dopergin, Proclacam, and Revanil, is an antiparkinson agent of the iso-ergoline class, chemically related to the dopaminergic ergoline Parkinson's drugs.

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Lysergic acid

Lysergic acid, also known as D-lysergic acid and (+)-lysergic acid, is a precursor for a wide range of ergoline alkaloids that are produced by the ergot fungus and found in the seeds of Turbina corymbosa (ololiuhqui), Argyreia nervosa (Hawaiian Baby Woodrose), and Ipomoea tricolor (morning glories, tlitliltzin).

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Lysergic acid diethylamide

Lysergic acid diethylamide (LSD), also known as acid, is a psychedelic drug known for its psychological effects, which may include altered awareness of one's surroundings, perceptions, and feelings as well as sensations and images that seem real though they are not.

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Lysergic acid hydroxyethylamide

-Lysergic acid α-hydroxyethylamide (LSH, LAH), also known as -lysergic acid methyl carbinolamide, is an alkaloid of the ergoline family, and is commonly misconceived as occurring in various species in the Convolvulaceae (morning glory) (LSA), family however does occur in some species of fungi.

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Lysergol

Lysergol is an alkaloid of the ergoline family that occurs as a minor constituent in some species of fungi (most within Claviceps), and in the morning glory family of plants (Convolvulaceae), including the hallucinogenic seeds of Rivea corymbosa (ololiuhqui), Argyreia nervosa (Hawaiian baby woodrose) and Ipomoea violacea.

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Methyl group

A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3.

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Methylergometrine

Methylergometrine (also called methylergonovine, methylergobasin, and D-lysergic acid 1-butanolamide) is a synthetic analogue of ergonovine, a psychedelic alkaloid found in ergot, and many species of morning glory.

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Methysergide

Methysergide (1-methyl-D-lysergic acid butanolamide or UML-491) also known as methysergide maleate, is an ergot derived prescription drug used for the prophylaxis of difficult to treat migraine and cluster headaches.

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Mexico

Mexico (México; Mēxihco), officially called the United Mexican States (Estados Unidos Mexicanos) is a federal republic in the southern portion of North America.

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Migraine

A migraine is a primary headache disorder characterized by recurrent headaches that are moderate to severe.

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Parkinson's disease

Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system.

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Peptide

Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.

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Pergolide

Pergolide (trade names Permax, Prascend) is an ergoline-based dopamine receptor agonist used in some countries for the treatment of Parkinson's disease (PD).

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Phenylalanine

Phenylalanine (symbol Phe or F) is an α-amino acid with the formula.

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Preferred IUPAC name

In chemical nomenclature, a preferred IUPAC name (PIN) is a unique name, assigned to a chemical substance and preferred among the possible names generated by IUPAC nomenclature.

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Proline

Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins.

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Propyl group

In organic chemistry, propyl is a three-carbon alkyl substituent with chemical formula – for the linear form.

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Psychedelic drug

Psychedelics are a class of drug whose primary action is to trigger psychedelic experiences via serotonin receptor agonism, causing thought and visual/auditory changes, and altered state of consciousness.

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Psychoactive drug

A psychoactive drug, psychopharmaceutical, or psychotropic is a chemical substance that changes brain function and results in alterations in perception, mood, consciousness, cognition, or behavior.

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Semisynthesis

Semisynthesis or partial chemical synthesis is a type of chemical synthesis that uses chemical compounds isolated from natural sources (e.g., microbial cell cultures or plant material) as the starting materials to produce other novel compounds with distinct chemical and medicinal properties.

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Structural formula

The structural formula of a chemical compound is a graphic representation of the molecular structure, showing how the atoms are arranged.

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Toxicity

Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism.

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Turbina corymbosa

Turbina corymbosa, syn. Rivea corymbosa, is a species of morning glory, native throughout Latin America from Mexico as far south as Peru and widely naturalised elsewhere.

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United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances

The United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances of 1988 is one of three major drug control treaties currently in force.

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Uterotonic

A uterotonic, also known as ecbolic, is an agent used to induce contraction or greater tonicity of the uterus.

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Valine

Valine (symbol Val or V) is an α-amino acid that is used in the biosynthesis of proteins.

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Vasoconstriction

Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles.

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5-HT1 receptor

The 5-HT1 receptors are a subfamily of the 5-HT serotonin receptors that bind to the endogenous neurotransmitter serotonin (also known as 5-hydroxytryptamine, or 5-HT).

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ATC code G02AB02, ATCvet code QG02AB02, Avetol, Clavine, Dihydroergoline, Dihydroergolines, Ergoline derivatives, Ergolines, Ergopeptide, Ergopeptides, Ergopeptine, Ergopeptines, Ergot alkaloid, Ergotamines, Ergotoxine.

References

[1] https://en.wikipedia.org/wiki/Ergoline

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