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Modified-release dosage

Index Modified-release dosage

Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release dosage) or to a specific target in the body (targeted-release dosage). [1]

44 relations: Acryloyl group, Active ingredient, Active transport, ALZA, Bioadhesive, Buoyancy, Capsule (pharmacy), Chitin, Contraceptive implant, Controlled-release fertiliser, Dosage form, Dose (biochemistry), Dose dumping, Drug, Drug carrier, Enteric coating, Excipient, Extended-release morphine, Food and Drug Administration, Gel, Half-life, Health information technology, Injection (medicine), Journal of Controlled Release, Laser drilling, Liberation (pharmacology), Liposome, Micro-encapsulation, Microelectromechanical systems, Modified-release dosage, Nanoelectromechanical systems, Osmosis, Osmotic pressure, Patent, PH, Pharmacokinetics, Route of administration, Semipermeable membrane, Side effect, Solvation, Tablet (pharmacy), Therapeutic index, Transdermal patch, Vaginal ring.

Acryloyl group

In organic chemistry, the acryloyl group is form of enone with structure H2C.

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Active ingredient

An active ingredient (AI) is the ingredient in a pharmaceutical drug that is biologically active.

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Active transport

Active transport is the movement of molecules across a membrane from a region of their lower concentration to a region of their higher concentration—in the direction against the concentration gradient.

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ALZA

ALZA Corporation was a pharmaceutical and medical systems company.

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Bioadhesive

Bioadhesives are natural polymeric materials that act as adhesives.

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Buoyancy

In physics, buoyancy or upthrust, is an upward force exerted by a fluid that opposes the weight of an immersed object.

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Capsule (pharmacy)

In the manufacture of pharmaceuticals, encapsulation refers to a range of dosage forms—techniques used to enclose medicines—in a relatively stable shell known as a capsule, allowing them to, for example, be taken orally or be used as suppositories.

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Chitin

Chitin (C8H13O5N)n, a long-chain polymer of ''N''-acetylglucosamine, is a derivative of glucose.

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Contraceptive implant

A contraceptive implant is an implantable medical device used for the purpose of birth control.

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Controlled-release fertiliser

A controlled-release fertiliser (CRF) is a granulated fertiliser that releases nutrients gradually into the soil (i.e., with a controlled release period).

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Dosage form

Dosage forms (also called unit doses) are pharmaceutical drug products in the form in which they are marketed for use, with a specific mixture of active ingredients and inactive components (excipients), in a particular configuration (such as a capsule shell, for example), and apportioned into a particular dose.

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Dose (biochemistry)

A dose is a measured quantity of a medicine, nutrient, or pathogen which is delivered as a unit.

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Dose dumping

Dose dumping is a phenomenon of drug metabolism in which environmental factors can cause the premature and exaggerated release of a drug.

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Drug

A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.

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Drug carrier

A drug carrier is any substrate used in the process of drug delivery which serves to improve the selectivity, effectiveness, and/or safety of drug administration.

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Enteric coating

An enteric coating is a polymer barrier applied on oral medication that prevents its dissolution or disintegration in the gastric environment.

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Excipient

An excipient is a substance formulated alongside the active ingredient of a medication, included for the purpose of long-term stabilization, bulking up solid formulations that contain potent active ingredients in small amounts (thus often referred to as "bulking agents", "fillers", or "diluents"), or to confer a therapeutic enhancement on the active ingredient in the final dosage form, such as facilitating drug absorption, reducing viscosity, or enhancing solubility.

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Extended-release morphine

Extended-release (or slow-release) formulations of morphine are those whose effect last substantially longer than bare morphine, availing for e.g. one administration per day.

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Food and Drug Administration

The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.

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Gel

A gel is a solid jelly-like material that can have properties ranging from soft and weak to hard and tough.

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Half-life

Half-life (symbol t1⁄2) is the time required for a quantity to reduce to half its initial value.

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Health information technology

Health information technology (HIT) is information technology applied to health and health care.

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Injection (medicine)

Injection (often referred to as a "shot" in US English, or a "jab" in UK English) is the act of putting a liquid, especially a drug, into a person's body using a needle (usually a hypodermic needle) and a syringe.

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Journal of Controlled Release

The Journal of Controlled Release is a biweekly peer-reviewed medical journal and the official journal of the Controlled Release Society.

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Laser drilling

Laser drilling is the process of creating thru-holes, referred to as “popped” holes or “percussion drilled” holes, by repeatedly pulsing focused laser energy on a material.

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Liberation (pharmacology)

Liberation is the first step in the process by which medication enters the body and liberates the active ingredient that has been administered.

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Liposome

A liposome is a spherical vesicle having at least one lipid bilayer.

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Micro-encapsulation

Microencapsulation is a process in which tiny particles or droplets are surrounded by a coating to give small capsules, of many useful properties.

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Microelectromechanical systems

Microelectromechanical systems (MEMS, also written as micro-electro-mechanical, MicroElectroMechanical or microelectronic and microelectromechanical systems and the related micromechatronics) is the technology of microscopic devices, particularly those with moving parts.

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Modified-release dosage

Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release dosage) or to a specific target in the body (targeted-release dosage).

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Nanoelectromechanical systems

Nanoelectromechanical systems (NEMS) are a class of devices integrating electrical and mechanical functionality on the nanoscale.

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Osmosis

Osmosis is the spontaneous net movement of solvent molecules through a selectively permeable membrane into a region of higher solute concentration, in the direction that tends to equalize the solute concentrations on the two sides.

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Osmotic pressure

Osmotic pressure is the minimum pressure which needs to be applied to a solution to prevent the inward flow of its pure solvent across a semipermeable membrane.

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Patent

A patent is a set of exclusive rights granted by a sovereign state or intergovernmental organization to an inventor or assignee for a limited period of time in exchange for detailed public disclosure of an invention.

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PH

In chemistry, pH is a logarithmic scale used to specify the acidity or basicity of an aqueous solution.

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Pharmacokinetics

Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism.

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Route of administration

A route of administration in pharmacology and toxicology is the path by which a drug, fluid, poison, or other substance is taken into the body.

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Semipermeable membrane

A semipermeable membrane is a type of biological or synthetic, polymeric membrane that will allow certain molecules or ions to pass through it by diffusion—or occasionally by more specialized processes of facilitated diffusion, passive transport or active transport.

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Side effect

In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.

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Solvation

Solvation describes the interaction of solvent with dissolved molecules.

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Tablet (pharmacy)

A tablet is a pharmaceutical dosage form.

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Therapeutic index

The therapeutic index (TI; also referred to as therapeutic ratio) is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes toxicity.

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Transdermal patch

A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream.

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Vaginal ring

Vaginal rings (also known as intravaginal rings, or V-Rings) are polymeric drug delivery devices designed to provide controlled release of drugs for intravaginal administration over extended periods of time.

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References

[1] https://en.wikipedia.org/wiki/Modified-release_dosage

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