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Basic fibroblast growth factor

Index Basic fibroblast growth factor

FGF2, also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by the FGF2 gene. [1]

41 relations: Adipocyte, Angiogenesis, Anxiety disorder, Basement membrane, Blood vessel, Bone morphogenetic protein, Bone morphogenetic protein 4, Casein kinase 2, alpha 1, Cell growth, Cell membrane, Cell signaling, Cellular differentiation, Chondrocyte, Cytokine, Embryogenesis, Embryonic stem cell, Endothelium, Enzyme, Extracellular matrix, Fibroblast growth factor, Fibroblast growth factor receptor, Fibroblast growth factor receptor 1, Gene, Gremlin (protein), Growth factor, Heparan sulfate, Mitogen, Morphogenesis, Neoplasm, Osteoblast, Phosphoinositide 3-kinase, Proteases in angiogenesis, Protein–protein interaction, Receptor (biochemistry), Reperfusion therapy, Signal peptide, Signal transduction, Tissue engineering, Wound healing, 40S ribosomal protein S19, 60S ribosomal protein L6.

Adipocyte

Adipocytes, also known as lipocytes and fat cells, are the cells that primarily compose adipose tissue, specialized in storing energy as fat.

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Angiogenesis

Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.

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Anxiety disorder

Anxiety disorders are a group of mental disorders characterized by significant feelings of anxiety and fear.

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Basement membrane

The basement membrane is a thin, fibrous, extracellular matrix of tissue that separates the lining of an internal or external body surface from underlying connective tissue in metazoans.

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Blood vessel

The blood vessels are the part of the circulatory system, and microcirculation, that transports blood throughout the human body.

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Bone morphogenetic protein

Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens.

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Bone morphogenetic protein 4

Bone morphogenetic protein 4 is a protein that in humans is encoded by BMP4 gene.

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Casein kinase 2, alpha 1

Casein kinase II subunit alpha is an enzyme that in humans is encoded by the CSNK2A1 gene.

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Cell growth

The term cell growth is used in the contexts of biological cell development and cell division (reproduction).

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Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).

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Cell signaling

Cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates all cell actions.

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Cellular differentiation

In developmental biology, cellular differentiation is the process where a cell changes from one cell type to another.

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Chondrocyte

Chondrocytes (from Greek χόνδρος, chondros.

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Cytokine

Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.

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Embryogenesis

Embryogenesis is the process by which the embryo forms and develops.

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Embryonic stem cell

Embryonic stem cells (ES cells or ESCs) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre-implantation embryo.

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Endothelium

Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Extracellular matrix

In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by support cells that provides structural and biochemical support to the surrounding cells.

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Fibroblast growth factor

The fibroblast growth factors are a family of cell signalling proteins that are involved in a wide variety of processes, most notably as crucial elements for normal development.

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Fibroblast growth factor receptor

The fibroblast growth factor receptors are, as their name implies, receptors that bind to members of the fibroblast growth factor family of proteins.

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Fibroblast growth factor receptor 1

Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Gremlin (protein)

Gremlin is an inhibitor in the TGF beta signaling pathway.

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Growth factor

A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation.

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Heparan sulfate

Heparan sulfate (HS) is a linear polysaccharide found in all animal tissues.

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Mitogen

A mitogen is a chemical substance that encourages a cell to commence cell division, triggering mitosis.

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Morphogenesis

Morphogenesis (from the Greek morphê shape and genesis creation, literally, "beginning of the shape") is the biological process that causes an organism to develop its shape.

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Neoplasm

Neoplasia is a type of abnormal and excessive growth of tissue.

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Osteoblast

Osteoblasts (from the Greek combining forms for "bone", ὀστέο-, osteo- and βλαστάνω, blastanō "germinate") are cells with a single nucleus that synthesize bone.

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Phosphoinositide 3-kinase

Phosphatidylinositol-4,5-bisphosphate 3-kinase (also called phosphatidylinositide 3-kinases, phosphatidylinositol-3-kinases, PI 3-kinases, PI(3)Ks, PI-3Ks or by the HUGO official stem symbol for the gene family, PI3K(s)) are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.

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Proteases in angiogenesis

Angiogenesis is the process of forming new blood vessels from existing blood vessels.

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Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

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Receptor (biochemistry)

In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.

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Reperfusion therapy

Reperfusion therapy is a medical treatment to restore blood flow, either through or around, blocked arteries, typically after a heart attack (myocardial infarction (MI)).

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Signal peptide

A signal peptide (sometimes referred to as signal sequence, targeting signal, localization signal, localization sequence, transit peptide, leader sequence or leader peptide) is a short peptide (usually 16-30 amino acids long) present at the N-terminus of the majority of newly synthesized proteins that are destined towards the secretory pathway.

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Signal transduction

Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.

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Tissue engineering

Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological tissues.

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Wound healing

Wound healing is an intricate process in which the skin repairs itself after injury.

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40S ribosomal protein S19

40S ribosomal protein S19 is a protein that in humans is encoded by the RPS19 gene.

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60S ribosomal protein L6

60S ribosomal protein L6 is a protein that in humans is encoded by the RPL6 gene.

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Redirects here:

BFGF, FGF-2, FGF-β, FGF2, FGF2 (gene), Fibroblast growing factor, Fibroblast growth factor 2.

References

[1] https://en.wikipedia.org/wiki/Basic_fibroblast_growth_factor

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