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134 relations: Achilles tendon, Acute bronchitis, Agency for Healthcare Research and Quality, Animal husbandry, Antacid, Anthrax, Antibiotic, Antimicrobial resistance, Antiviral drug, Atom, Azithromycin, Bactericide, Balofloxacin, Benzodiazepine dependence, Benzodiazepine withdrawal syndrome, Besifloxacin, Bicyclic molecule, Boxed warning, Broad-spectrum antibiotic, Ceftriaxone, Central nervous system, Cephalosporin, Chemical nomenclature, Chloroquine, Ciclosporin, Cimetidine, Cinoxacin, Ciprofloxacin, Clinafloxacin, Clindamycin, Clostridium difficile (bacteria), Clostridium difficile infection, Cmax (pharmacology), Cycloserine, Cystic fibrosis, Cytochrome P450, Danofloxacin, Delafloxacin, Difloxacin, Distillation, DNA, DNA gyrase, DNA replication, Dose (biochemistry), Drug, Efflux (microbiology), Ehlers–Danlos syndromes, Elimination (pharmacology), Enoxacin, Enrofloxacin, ..., Epilepsy, Escherichia coli, Fleroxacin, Flumequine, Fluorine, Food and Drug Administration, Garenoxacin, Gatifloxacin, Gemifloxacin, Gram-negative bacteria, Gram-positive bacteria, Grepafloxacin, Heart arrhythmia, Hypersensitivity, Ibafloxacin, Infection, Intracellular, Ion, Legionella pneumophila, Levofloxacin, Lomefloxacin, Macrolide, Marbofloxacin, Mitochondrial DNA, Moxifloxacin, Mutation, Myasthenia gravis, Mycoplasma pneumoniae, Nadifloxacin, Nalidixic acid, Norfloxacin, Ofloxacin, Orbifloxacin, Osteomyelitis, Otitis media, Oxolinic acid, Ozenoxacin, Pathogen, Pazufloxacin, Pefloxacin, Penicillin, Pharmacophore, Phenytoin, Pipemidic acid, Piromidic acid, Plasma protein binding, Porin (protein), Probenecid, Prostatitis, Prulifloxacin, Pseudomonas, Public Citizen, Pyelonephritis, Pyrazinamide, QT interval, Quinoline, Rifampicin, Rosoxacin, Rufloxacin, Salmonella, Sarafloxacin, Sickle cell disease, Sitafloxacin, Sparfloxacin, Streptococcus, Streptococcus pneumoniae, Stroke, Structural analog, Sucralfate, Sulfonamide, Temafloxacin, Tetracycline antibiotics, The Wall Street Journal, Theophylline, Topoisomerase IV, Torsades de pointes, Tosufloxacin, Transcription (biology), Trovafloxacin, Type II topoisomerase, Urinary tract infection, Vancomycin, Warfarin, 4-Quinolone. Expand index (84 more) »
Achilles tendon
The Achilles tendon or heel cord, also known as the calcaneal tendon, is a tendon of the back of the leg, and the thickest in the human body.
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Acute bronchitis
Acute bronchitis, also known as a chest cold, is short-term inflammation of the bronchi (large and medium-sized airways) of the lungs.
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Agency for Healthcare Research and Quality
The Agency for Healthcare Research and Quality (AHRQ), located in Rockville, MD, a suburb of Washington, D.C., is one of 12 Agencies within the United States Department of Health and Human Services (HHS).
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Animal husbandry
Animal husbandry is the branch of agriculture concerned with animals that are raised for meat, fibre, milk, eggs, or other products.
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Antacid
An antacid is a substance which neutralizes stomach acidity and is used to relieve heartburn, indigestion or an upset stomach.
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Anthrax
Anthrax is an infection caused by the bacterium Bacillus anthracis.
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Antibiotic
An antibiotic (from ancient Greek αντιβιοτικά, antibiotiká), also called an antibacterial, is a type of antimicrobial drug used in the treatment and prevention of bacterial infections.
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Antimicrobial resistance
Antimicrobial resistance (AMR or AR) is the ability of a microbe to resist the effects of medication that once could successfully treat the microbe.
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Antiviral drug
Antiviral drugs are a class of medication used specifically for treating viral infections rather than bacterial ones.
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Atom
An atom is the smallest constituent unit of ordinary matter that has the properties of a chemical element.
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Azithromycin
Azithromycin is an antibiotic useful for the treatment of a number of bacterial infections.
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Bactericide
A bactericide or bacteriocide, sometimes abbreviated Bcidal, is a substance that kills bacteria.
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Balofloxacin
Balofloxacin (INN) is a fluoroquinolone antibiotic.
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Benzodiazepine dependence
Benzodiazepine dependence or benzodiazepine addiction is when one has developed one or more of either tolerance, withdrawal symptoms, drug seeking behaviors, such as continued use despite harmful effects, and maladaptive pattern of substance use, according to the DSM-IV.
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Benzodiazepine withdrawal syndrome
Benzodiazepine withdrawal syndrome—often abbreviated to benzo withdrawal—is the cluster of symptoms that emerge when a person who has taken benzodiazepines, either medically or recreationally, and has developed a physical dependence undergoes dosage reduction or discontinuation.
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Besifloxacin
Besifloxacin (INN/USAN) is a fourth-generation fluoroquinolone antibiotic.
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Bicyclic molecule
A bicyclic molecule (bi.
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Boxed warning
In the United States, a boxed warning (sometimes "black box warning", colloquially) is a type of warning that appears on the package insert for certain prescription drugs, so called because the U.S. Food and Drug Administration specifies that it is formatted with a 'box' or border around the text.
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Broad-spectrum antibiotic
The term broad-spectrum antibiotic can refer to an antibiotic that acts on the two major bacterial groups, gram-positive and gram-negative, or any antibiotic that acts against a wide range of disease-causing bacteria.
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Ceftriaxone
Ceftriaxone, sold under the trade name Rocephin, is an antibiotic useful for the treatment of a number of bacterial infections.
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Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
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Cephalosporin
The cephalosporins (sg.) are a class of β-lactam antibiotics originally derived from the fungus Acremonium, which was previously known as "Cephalosporium".
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Chemical nomenclature
A chemical nomenclature is a set of rules to generate systematic names for chemical compounds.
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Chloroquine
Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects.
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Ciclosporin
Ciclosporin, also spelled cyclosporine and cyclosporin, is an immunosuppressant medication and natural product.
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Cimetidine
Cimetidine, sold under the brand name Tagamet among others, is a histamine H2 receptor antagonist that inhibits stomach acid production.
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Cinoxacin
Cinoxacin is a quinolone antibiotic that has been discontinued in the U.K. as well the United States, both as a branded drug or a generic.
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Ciprofloxacin
Ciprofloxacin is an antibiotic used to treat a number of bacterial infections.
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Clinafloxacin
Clinafloxacin is an investigational fluoroquinolone antibiotic.
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Clindamycin
Clindamycin is an antibiotic useful for the treatment of a number of bacterial infections.
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Clostridium difficile (bacteria)
Clostridium difficile (etymology and pronunciation), also known as C. difficile, C. diff, or sometimes CDF/cdf, is a species of Gram-positive spore-forming bacterium.
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Clostridium difficile infection
Clostridium difficile infection (CDI or C-dif) is a symptomatic infection due to the spore-forming bacterium, Clostridium difficile.
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Cmax (pharmacology)
Cmax is the maximum (or peak) serum concentration that a drug achieves in a specified compartment or test area of the body after the drug has been administrated and before the administration of a second dose.
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Cycloserine
Cycloserine, sold under the brand name Seromycin, is an antibiotic used to treat tuberculosis.
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Cystic fibrosis
Cystic fibrosis (CF) is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine.
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Cytochrome P450
Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.
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Danofloxacin
Danofloxacin is a fluoroquinolone antibiotic used in veterinary medicine.
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Delafloxacin
Delafloxacin (INN) (trade name Baxdela) is a fluoroquinolone antibiotic used to treat acute bacterial skin and skin structure infections.
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Difloxacin
Difloxacin (INN), marketed under the trade name Dicural, is a second-generation, synthetic fluoroquinolone antibiotic used in veterinary medicine.
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Distillation
Distillation is the process of separating the components or substances from a liquid mixture by selective boiling and condensation.
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DNA
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
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DNA gyrase
DNA gyrase, or simply gyrase, is an enzyme within the class of topoisomerase (Type II topoisomerase) that relieves strain while double-stranded DNA is being unwound by helicase.
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DNA replication
In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.
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Dose (biochemistry)
A dose is a measured quantity of a medicine, nutrient, or pathogen which is delivered as a unit.
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Drug
A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.
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Efflux (microbiology)
Active efflux is a mechanism responsible for moving compounds, like neurotransmitters, toxic substances, and antibiotics, out of the cell; this is considered to be a vital part of xenobiotic metabolism.
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Ehlers–Danlos syndromes
Ehlers–Danlos syndromes (EDS) are a group of genetic connective tissue disorders.
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Elimination (pharmacology)
In pharmacology the elimination or excretion of a drug is understood to be any one of a number of processes by which a drug is eliminated (that is, cleared and excreted) from an organism either in an unaltered form (unbound molecules) or modified as a metabolite.
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Enoxacin
EnoxacinEnoxacin is sold under the following trade names: Almitil, Bactidan, Bactidron, Comprecin, Enoksetin, Enoxen, Enroxil, Enoxin, Enoxor, Flumark, Penetrex, Gyramid, Vinone.
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Enrofloxacin
Enrofloxacin (ENR) is a fluoroquinolone antibiotic sold by the Bayer Corporation under the trade name Baytril.
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Epilepsy
Epilepsy is a group of neurological disorders characterized by epileptic seizures.
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Escherichia coli
Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).
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Fleroxacin
Fleroxacin is a quinolone antibiotic.
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Flumequine
Flumequine is a synthetic fluoroquinolone antibiotic used to treat bacterial infections.
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Fluorine
Fluorine is a chemical element with symbol F and atomic number 9.
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Food and Drug Administration
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
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Garenoxacin
Garenoxacin (INN) is a quinolone antibiotic for the treatment of Gram-positive and Gram-negative bacterial infections.
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Gatifloxacin
Gatifloxacin sold under the brand names Gatiflo, Tequin and Zymar, is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.
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Gemifloxacin
Gemifloxacin mesylate (trade name Factive, Oscient Pharmaceuticals) is an oral broad-spectrum quinolone antibacterial agent used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia.
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Gram-negative bacteria
Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the gram-staining method of bacterial differentiation.
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Gram-positive bacteria
Gram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their cell wall.
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Grepafloxacin
Grepafloxacin hydrochloride (trade name Raxar, Glaxo Wellcome) was an oral broad-spectrum fluoroquinolone antibacterial agent used to treat bacterial infections.
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Heart arrhythmia
Heart arrhythmia (also known as arrhythmia, dysrhythmia, or irregular heartbeat) is a group of conditions in which the heartbeat is irregular, too fast, or too slow.
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Hypersensitivity
Hypersensitivity (also called hypersensitivity reaction or intolerance) refers to undesirable reactions produced by the normal immune system, including allergies and autoimmunity.
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Ibafloxacin
Ibafloxacin (INN) is a Fluoroquinolone antibiotic drug used in veterinary medicine.
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Infection
Infection is the invasion of an organism's body tissues by disease-causing agents, their multiplication, and the reaction of host tissues to the infectious agents and the toxins they produce.
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Intracellular
In cell biology, molecular biology and related fields, the word intracellular means "inside the cell".
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Ion
An ion is an atom or molecule that has a non-zero net electrical charge (its total number of electrons is not equal to its total number of protons).
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Legionella pneumophila
Legionella pneumophila is a thin, aerobic, pleomorphic, flagellated, nonspore-forming, Gram-negative bacterium of the genus Legionella.
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Levofloxacin
Levofloxacin, sold under the trade names Levaquin among others, is an antibiotic.
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Lomefloxacin
Lomefloxacin hydrochloride (sold under the following brand names in English speaking countries Maxaquin, Okacyn, Uniquin) is a fluoroquinolone antibiotic used to treat bacterial infections including bronchitis and urinary tract infections.
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Macrolide
The macrolides are a class of natural products that consist of a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached.
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Marbofloxacin
Marbofloxacin is a carboxylic acid derivative third generation fluoroquinolone antibiotic.
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Mitochondrial DNA
Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, adenosine triphosphate (ATP).
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Moxifloxacin
Moxifloxacin, sold under the brandname Avelox among others, is an antibiotic used to treat a number of bacterial infections.
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Mutation
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.
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Myasthenia gravis
Myasthenia gravis (MG) is a long-term neuromuscular disease that leads to varying degrees of skeletal muscle weakness.
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Mycoplasma pneumoniae
Mycoplasma pneumoniae is a very small bacterium in the class Mollicutes.
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Nadifloxacin
Nadifloxacin (INN, brand names Acuatim, Nadiflox, Nadoxin, Nadixa, activon) is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris.
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Nalidixic acid
Nalidixic acid (tradenames Nevigramon, Neggram, Wintomylon and WIN 18,320) is the first of the synthetic quinolone antibiotics.
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Norfloxacin
Norfloxacin is a synthetic antibacterial agent that belongs to the class of fluoroquinolone antibiotics.
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Ofloxacin
Ofloxacin is an antibiotic useful for the treatment of a number of bacterial infections.
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Orbifloxacin
Orbifloxacin (brand name Orbax) is a fluoroquinolone antibiotic which is approved for use in dogs, marketed by Schering-Plough Animal Health.
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Osteomyelitis
Osteomyelitis (OM) is an infection of bone.
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Otitis media
Otitis media is a group of inflammatory diseases of the middle ear.
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Oxolinic acid
Oxolinic acid is a quinolone antibiotic developed in Japan in the 1970s.
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Ozenoxacin
Ozenoxacin (INN; trade names Ozaenex and Xepi) is a quinolone antibiotic being approved for the treatment of impetigo.
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Pathogen
In biology, a pathogen (πάθος pathos "suffering, passion" and -γενής -genēs "producer of") or a '''germ''' in the oldest and broadest sense is anything that can produce disease; the term came into use in the 1880s.
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Pazufloxacin
Pazufloxacin (INN) is a fluoroquinolone antibiotic.
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Pefloxacin
Pefloxacin is a quinolone antibiotic used to treat bacterial infections.
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Penicillin
Penicillin (PCN or pen) is a group of antibiotics which include penicillin G (intravenous use), penicillin V (use by mouth), procaine penicillin, and benzathine penicillin (intramuscular use).
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Pharmacophore
An example of a pharmacophore model. A pharmacophore is an abstract description of molecular features that are necessary for molecular recognition of a ligand by a biological macromolecule.
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Phenytoin
Phenytoin (PHT), sold under the brand name Dilantin among others, is an anti-seizure medication.
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Pipemidic acid
Pipemidic acid is a member of the pyridopyrimidine class of antibacterials, which display some overlap in mechanism of action with analogous pyridone-containing quinolones.
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Piromidic acid
Piromidic acid is a quinolone antibiotic.
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Plasma protein binding
Plasma protein binding refers to the degree to which medications attach to proteins within the blood.
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Porin (protein)
Porins are beta barrel proteins that cross a cellular membrane and act as a pore, through which molecules can diffuse.
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Probenecid
Probenecid, also sold under the brandname Probalan, is a medication that increases uric acid excretion in the urine.
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Prostatitis
Prostatitis is inflammation of the prostate gland.
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Prulifloxacin
Prulifloxacin is an older synthetic antibiotic of the fluoroquinolone class undergoing clinical trials prior to a possible NDA (New Drug Application) submission to the U.S. Food and Drug Administration (FDA).
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Pseudomonas
Pseudomonas is a genus of Gram-negative, Gammaproteobacteria, belonging to the family Pseudomonadaceae and containing 191 validly described species.
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Public Citizen
Public Citizen is a non-profit, liberal / progressive consumer rights advocacy group and think tank based in Washington, D.C., United States, with a branch in Austin, Texas.
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Pyelonephritis
Pyelonephritis is inflammation of the kidney, typically due to a bacterial infection.
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Pyrazinamide
Pyrazinamide is a medication used to treat tuberculosis.
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QT interval
In cardiology, the QT interval is a measure of the time between the start of the Q wave and the end of the T wave in the heart's electrical cycle.
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Quinoline
Quinoline is a heterocyclic aromatic organic compound with the chemical formula C9H7N.
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Rifampicin
Rifampicin, also known as rifampin, is an antibiotic used to treat several types of bacterial infections, including tuberculosis, leprosy, and Legionnaire's disease.
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Rosoxacin
Rosoxacin (also known as acrosoxacin, tradename Eradacil) is a quinolone antibiotic indicated for the treatment of urinary tract infections and certain sexually transmitted diseases.
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Rufloxacin
Rufloxacin is a quinolone antibiotic.
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Salmonella
Salmonella is a genus of rod-shaped (bacillus) Gram-negative bacteria of the family Enterobacteriaceae.
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Sarafloxacin
Sarafloxacin (INN) is a quinolone antibiotic drug, which was removed from clinical use by its manufacturer Abbott Laboratories from April 30, 2001.
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Sickle cell disease
Sickle cell disease (SCD) is a group of blood disorders typically inherited from a person's parents.
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Sitafloxacin
Sitafloxacin (INN; also called DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer.
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Sparfloxacin
Sparfloxacin (spar FLOX a sin), trade names Spacin in Bangladesh, Zagam and Zagam Respipac, is a fluoroquinolone antibiotic used in the treatment of bacterial infections.
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Streptococcus
Streptococcus (term coined by Viennese surgeon Albert Theodor Billroth (1829-1894) from strepto- "twisted" + Modern Latin coccus "spherical bacterium," from Greek kokkos meaning "berry") is a genus of coccus (spherical) Gram-positive bacteria belonging to the phylum Firmicutes and the order Lactobacillales (lactic acid bacteria).
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Streptococcus pneumoniae
Streptococcus pneumoniae, or pneumococcus, is a Gram-positive, alpha-hemolytic (under aerobic conditions) or beta-hemolytic (under anaerobic conditions), facultative anaerobic member of the genus Streptococcus.
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Stroke
A stroke is a medical condition in which poor blood flow to the brain results in cell death.
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Structural analog
A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.
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Sucralfate
Sucralfate is a medication primarily taken to treat active duodenal ulcers. Sucralfate is also used for the treatment of gastroesophageal reflux disease (GERD) and stress ulcers. Sucralfate is a sucrose sulfate-aluminium complex that binds to the ulcer, creating a physical barrier that protects the gastrointestinal tract from stomach acid and prevents the degradation of mucus. It also promotes bicarbonate production and acts like an acid buffer with cytoprotective properties.
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Sulfonamide
In chemistry, the sulfonamide functional group (also spelled sulphonamide) is -S(.
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Temafloxacin
Temafloxacin (marketed by Abbott Laboratories as Omniflox) is a fluoroquinolone antibiotic drug which was withdrawn from sale in the United States shortly after its approval in 1992 because of serious adverse effects resulting in three deaths.
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Tetracycline antibiotics
Tetracyclines are broad-spectrum antibiotics whose general usefulness has been reduced with the onset of antibiotic resistance.
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The Wall Street Journal
The Wall Street Journal is a U.S. business-focused, English-language international daily newspaper based in New York City.
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Theophylline
Theophylline, also known as 1,3-dimethylxanthine, is a methylxanthine drug used in therapy for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma under a variety of brand names.
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Topoisomerase IV
Topoisomerase IV is one of two type-II topoisomerases in bacteria, the other being DNA gyrase.
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Torsades de pointes
Torsades de pointes or torsade depointes (TdP or simply torsade(s)) (translated as "twisting of the points"), is a specific type of abnormal heart rhythm that can lead to sudden cardiac death.
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Tosufloxacin
Tosufloxacin is a fluoroquinolone antibiotic.
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Transcription (biology)
Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.
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Trovafloxacin
Trovafloxacin (sold as Trovan by Pfizer and Turvel by Laboratorios Almirall) was a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in various bacteria by blocking the activity of DNA gyrase and topoisomerase IV.
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Type II topoisomerase
Type II topoisomerases cut both strands of the DNA helix simultaneously in order to manage DNA tangles and supercoils.
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Urinary tract infection
A urinary tract infection (UTI) is an infection that affects part of the urinary tract.
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Vancomycin
Vancomycin is an antibiotic used to treat a number of bacterial infections.
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Warfarin
Warfarin, sold under the brand name Coumadin among others, is a medication that is used as an anticoagulant (blood thinner).
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4-Quinolone
4-Quinolone is an organic compound derived from quinoline.
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Redirects here:
2- and 4-Quinolones, Adverse effects of fluoroquinolones, Adverse effects of quinolones, Adverse reaction to fluoroquinolone, FQAD, FQTS, Flouroquinolone, Fluoroquinolone, Fluoroquinolone Toxicity, Fluoroquinolone Toxicity Syndrome, Fluoroquinolone adverse reactions, Fluoroquinolone antibiotic, Fluoroquinolone antibiotics, Fluoroquinolone toxicity, Fluoroquinolone toxicity syndrome, Fluoroquinolone-associated disability, Fluoroquinolones, Quinolone anitbiotics, Quinolone antibiotics, Quinolone toxicity syndrome, Quinolone-induced tendonopathy.
References
[1] https://en.wikipedia.org/wiki/Quinolone_antibiotic
