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44 relations: Anticoagulant, Arginine, Bleeding, C-terminus, Calcium, Calcium in biology, Ceruloplasmin, Chromosome 1, Chronic liver disease, Coagulation, Cofactor (biochemistry), Discoidin domain, Dominance (genetics), Factor V Leiden, Factor VIII, Factor X, Fibrinogen, Gene, Glutamine, Haemophilia, Homology (biology), Menorrhagia, Multicopper oxidase, Mutation, Norway, Nosebleed, Paul Morawitz, Phospholipid, Platelet, Protein, Protein C, Protein S, Protein–protein interaction, Prothrombin time, Prothrombinase, The Lancet, Thrombin, Thrombomodulin, Thrombophilia, Thrombosis, Thrombus, Venous thrombosis, Vitamin K, World War II.
Anticoagulant
Anticoagulants, commonly referred to as blood thinners, are chemical substances that prevent or reduce coagulation of blood, prolonging the clotting time.
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Arginine
Arginine (symbol Arg or R) is an α-amino acid that is used in the biosynthesis of proteins.
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Bleeding
Bleeding, also known as hemorrhaging or haemorrhaging, is blood escaping from the circulatory system.
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C-terminus
The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).
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Calcium
Calcium is a chemical element with symbol Ca and atomic number 20.
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Calcium in biology
Calcium ions (Ca2+) play a vital role in the physiology and biochemistry of organisms and the cell.
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Ceruloplasmin
Ceruloplasmin (or caeruloplasmin) is a ferroxidase enzyme that in humans is encoded by the CP gene.
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Chromosome 1
Chromosome 1 is the designation for the largest human chromosome.
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Chronic liver disease
Chronic liver disease in the clinical context is a disease process of the liver that involves a process of progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis.
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Coagulation
Coagulation (also known as clotting) is the process by which blood changes from a liquid to a gel, forming a blood clot.
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Cofactor (biochemistry)
A cofactor is a non-protein chemical compound or metallic ion that is required for an enzyme's activity.
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Discoidin domain
Discoidin domain (also known as F5/8 type C domain, or C2-like domain) is major protein domain of many blood coagulation factors.
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Dominance (genetics)
Dominance in genetics is a relationship between alleles of one gene, in which the effect on phenotype of one allele masks the contribution of a second allele at the same locus.
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Factor V Leiden
Factor V Leiden (rs6025) is a variant (mutated form) of human factor V (one of several substances that helps blood clot), which causes an increase in blood clotting (hypercoagulability).
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Factor VIII
Factor VIII (FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor (AHF).
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Factor X
Factor X, also known by the eponym Stuart–Prower factor, is an enzyme of the coagulation cascade.
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Fibrinogen
Fibrinogen (factor I) is a glycoprotein that in vertebrates circulates in the blood.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Glutamine
Glutamine (symbol Gln or Q) is an α-amino acid that is used in the biosynthesis of proteins.
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Haemophilia
Haemophilia, also spelled hemophilia, is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding.
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Homology (biology)
In biology, homology is the existence of shared ancestry between a pair of structures, or genes, in different taxa.
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Menorrhagia
Menorrhagia is a menstrual period with excessively heavy flow and falls under the larger category of abnormal uterine bleeding (AUB).
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Multicopper oxidase
In molecular biology, multicopper oxidases are enzymes which oxidise their substrate by accepting electrons at a mononuclear copper centre and transferring them to a trinuclear copper centre; dioxygen binds to the trinuclear centre and, following the transfer of four electrons, is reduced to two molecules of water.
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Mutation
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.
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Norway
Norway (Norwegian: (Bokmål) or (Nynorsk); Norga), officially the Kingdom of Norway, is a unitary sovereign state whose territory comprises the western portion of the Scandinavian Peninsula plus the remote island of Jan Mayen and the archipelago of Svalbard.
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Nosebleed
A nosebleed, also known as epistaxis, is the common occurrence of bleeding from the nose.
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Paul Morawitz
Paul Oskar Morawitz (April 3, 1879 in St. Petersburg – July 1, 1936) was a German internist and physiologist whose most important work was in studying the coagulation of blood.
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Phospholipid
Phospholipids are a class of lipids that are a major component of all cell membranes.
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Platelet
Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein C
Protein C, also known as autoprothrombin IIA and blood coagulation factor XIV, is a zymogen, the activated form of which plays an important role in regulating anticoagulation, inflammation, cell death, and maintaining the permeability of blood vessel walls in humans and other animals.
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Protein S
Protein S (also known as S-Protein) is a vitamin K-dependent plasma glycoprotein synthesized in the liver.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Prothrombin time
The prothrombin time (PT)—along with its derived measures of prothrombin ratio (PR) and international normalized ratio (INR)—are assays evaluating the extrinsic pathway of coagulation.
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Prothrombinase
The prothrombinase complex consists of the serine protein, Factor Xa, and the protein cofactor, Factor Va.
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The Lancet
The Lancet is a weekly peer-reviewed general medical journal.
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Thrombin
Thrombin (fibrinogenase, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated blood-coagulation factor II, blood-coagulation factor IIa, factor IIa, E thrombin, beta-thrombin, gamma-thrombin) is a serine protease, an enzyme that, in humans, is encoded by the F2 gene.
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Thrombomodulin
Thrombomodulin (TM), CD141 or BDCA-3 is an integral membrane protein expressed on the surface of endothelial cells and serves as a cofactor for thrombin.
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Thrombophilia
Thrombophilia (sometimes hypercoagulability or a prothrombotic state) is an abnormality of blood coagulation that increases the risk of thrombosis (blood clots in blood vessels).
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Thrombosis
Thrombosis (from Ancient Greek θρόμβωσις thrómbōsis "clotting”) is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.
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Thrombus
A thrombus, colloquially called a blood clot, is the final product of the blood coagulation step in hemostasis.
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Venous thrombosis
A venous thrombus is a blood clot (thrombus) that forms within a vein.
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Vitamin K
Vitamin K is a group of structurally similar, fat-soluble vitamins that the human body requires for complete synthesis of certain proteins that are prerequisites for blood coagulation (K from Koagulation, Danish for "coagulation") and which the body also needs for controlling binding of calcium in bones and other tissues.
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World War II
World War II (often abbreviated to WWII or WW2), also known as the Second World War, was a global war that lasted from 1939 to 1945, although conflicts reflecting the ideological clash between what would become the Allied and Axis blocs began earlier.
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Redirects here:
Coagulation factor V deficiency, F5 (gene), FV gene, Factor V deficiency, Factor Va, Factor v, Factor v deficiency, Factor va, Parahaemophilia, Proaccelerin.
References
[1] https://en.wikipedia.org/wiki/Factor_V
