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35 relations: Alternative splicing, Apoptosis, Bcl-2, Bcl-2 homologous antagonist killer, Bcl-2-associated X protein, Bcl-xL, BH3 interacting-domain death agonist, Caspase 10, Caspase 8, CFLAR, Chromosome 10, Cluster of differentiation, Crosstalk (biology), Cytochrome c, Death effector domain, Death-inducing signaling complex, Endosome, Exon, FADD, Fas ligand, Gene, Haplotype, Homology (biology), Inhibitor of apoptosis, Mammal, PDCD6, Protease, Protein, Protein isoform, Protein–protein interaction, Signal transducing adaptor protein, Small ubiquitin-related modifier 1, TIA1, TNF receptor superfamily, Transmembrane protein.
Alternative splicing
Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.
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Apoptosis
Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.
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Bcl-2
Bcl-2 (B-cell lymphoma 2), encoded in humans by the BCL2 gene, is the founding member of the Bcl-2 family of regulator proteins that regulate cell death (apoptosis), by either inducing (pro-apoptotic) or inhibiting (anti-apoptotic) apoptosis.
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Bcl-2 homologous antagonist killer
Bcl-2 homologous antagonist/killer is a protein that in humans is encoded by the BAK1 gene on chromosome 6.
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Bcl-2-associated X protein
Apoptosis regulator BAX, also known as bcl-2-like protein 4, is a protein that in humans is encoded by the BAX gene.
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Bcl-xL
B-cell lymphoma-extra large (Bcl-xL), encoded by the BCL2-like 1 gene, is a transmembrane molecule in the mitochondria.
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BH3 interacting-domain death agonist
The BH3 interacting-domain death agonist, or BID, gene is a pro-apoptotic member of the Bcl-2 protein family.
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Caspase 10
Caspase-10 is an enzyme that, in humans, is encoded by the CASP10 gene.
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Caspase 8
Caspase-8 is a caspase protein, encoded by the CASP8 gene.
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CFLAR
CASP8 and FADD-like apoptosis regulator is a protein that in humans is encoded by the CFLAR gene.
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Chromosome 10
Chromosome 10 is one of the 23 pairs of chromosomes in humans.
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Cluster of differentiation
The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells.
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Crosstalk (biology)
Biological crosstalk refers to instances in which one or more components of one signal transduction pathway affects another.
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Cytochrome c
The cytochrome complex, or cyt c is a small hemeprotein found loosely associated with the inner membrane of the mitochondrion.
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Death effector domain
The death-effector domain (DED) is a protein interaction domain found only in eukaryotes that regulates a variety of cellular signalling pathways.
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Death-inducing signaling complex
The death-inducing signaling complex or DISC is a multi-protein complex formed by members of the "death receptor" family of apoptosis-inducing cellular receptors.
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Endosome
In cell biology, an endosome is a membrane-bound compartment inside eukaryotic cells.
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Exon
An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.
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FADD
Fas-associated protein with death domain (FADD), also called MORT1, is encoded by the FADD gene on the 11q13.3 region of chromosome 11 in humans.
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Fas ligand
Fas ligand (FasL or CD95L) is a type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Haplotype
A haplotype (haploid genotype) is a group of alleles in an organism that are inherited together from a single parent.
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Homology (biology)
In biology, homology is the existence of shared ancestry between a pair of structures, or genes, in different taxa.
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Inhibitor of apoptosis
Apoptosis, or programmed cell death, is a highly regulated process used by many multicellular organisms.
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Mammal
Mammals are the vertebrates within the class Mammalia (from Latin mamma "breast"), a clade of endothermic amniotes distinguished from reptiles (including birds) by the possession of a neocortex (a region of the brain), hair, three middle ear bones, and mammary glands.
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PDCD6
Programmed cell death protein 6 is a protein that in humans is encoded by the PDCD6 gene.
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Protease
A protease (also called a peptidase or proteinase) is an enzyme that performs proteolysis: protein catabolism by hydrolysis of peptide bonds.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein isoform
A protein isoform, or "protein variant" is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Signal transducing adaptor protein
Signal transducing adaptor proteins are proteins that are accessory to main proteins in a signal transduction pathway.
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Small ubiquitin-related modifier 1
Small ubiquitin-related modifier 1 is a protein that in humans is encoded by the SUMO1 gene.
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TIA1
TIA1 is a 3'UTR mRNA binding protein that can bind the 5'TOP sequence of 5'TOP mRNAs.
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TNF receptor superfamily
The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis factors (TNFs) via an extracellular cysteine-rich domain.
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Transmembrane protein
A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the biological membrane to which it is permanently attached.
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APO-1, Antigens, cd95, CD95, FAS (gene), FasR, TNFRSF6.
References
[1] https://en.wikipedia.org/wiki/Fas_receptor
