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Fludrocortisone (also called 9α-fluorocortisol or 9α-fluorohydrocortisone) is a synthetic corticosteroid with moderate glucocorticoid potency and much greater mineralocorticoid potency. [1]

27 relations: Addison's disease, Adrenal insufficiency, Aldosterone, Bioisostere, Cataract, Cerebral salt-wasting syndrome, Congenital adrenal hyperplasia, Congenital adrenal hyperplasia due to 21-hydroxylase deficiency, Corticosteroid, Cortisol, Edema, Electronegativity, Glaucoma, Glucocorticoid, Health system, Hirsutism, Hypertension, Hypokalemia, Indigestion, Insomnia, Intracranial pressure, Mineralocorticoid, Orthostatic intolerance, Peptic ulcer, Postural orthostatic tachycardia syndrome, Primary aldosteronism, WHO Model List of Essential Medicines.

Addison's disease

Addison’s disease (also Addison disease, chronic adrenal insufficiency, hypocortisolism, and hypoadrenalism) is a rare, chronic endocrine system disorder in which the adrenal glands do not produce sufficient steroid hormones (glucocorticoids and mineralocorticoids).

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Adrenal insufficiency

Adrenal insufficiency is a condition in which the adrenal glands do not produce adequate amounts of steroid hormones, primarily cortisol; but may also include impaired production of aldosterone (a mineralocorticoid), which regulates sodium conservation, potassium secretion, and water retention.

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Aldosterone is a steroid hormone (mineralocorticoid family) produced by the outer section (zona glomerulosa) of the adrenal cortex in the adrenal gland.

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In medicinal chemistry, bioisosteres are chemical substituents or groups with similar physical or chemical properties which produce broadly similar biological properties to another chemical compound.

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A cataract is a clouding of the lens in the eye leading to a decrease in vision.

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Cerebral salt-wasting syndrome

Cerebral salt-wasting syndrome (CSWS) is a rare endocrine condition featuring a low blood sodium concentration and dehydration in response to trauma/injury or the presence of tumors in or surrounding the brain.

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Congenital adrenal hyperplasia

Congenital adrenal hyperplasia (CAH) are any of several autosomal recessive diseases resulting from mutations of genes for enzymes mediating the biochemical steps of production of cortisol from cholesterol by the adrenal glands (steroidogenesis).

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Congenital adrenal hyperplasia due to 21-hydroxylase deficiency

Congenital adrenal hyperplasia due to 21-hydroxylase deficiency (21-OH CAH), in all its forms, accounts for over 95% of diagnosed cases of congenital adrenal hyperplasia, and "CAH" in most contexts refers to 21-hydroxylase deficiency.

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Corticosteroids are a class of chemicals that includes the steroid hormones that are produced in the adrenal cortex of vertebrates as well as the synthetic analogues of these hormones.

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Cortisol is a steroid hormone, in the glucocorticoid class of hormones, and is produced in humans by the zona fasciculata of the adrenal cortex within the adrenal gland.

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Edema (also oedema, dropsy, and hydropsy) (Greek οἴδημα oídēma, "swelling") is an abnormal accumulation of fluid in the interstitium, located beneath the skin and in the cavities of the body which cause severe pain.

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Electronegativity, symbol χ, is a chemical property that describes the tendency of an atom or a functional group to attract electrons (or electron density) towards itself.

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Glaucoma is a term for a group of eye disorders which result in damage to the optic nerve.

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Glucocorticoids (GCs) are a class of steroid hormones which bind to the glucocorticoid receptor (GR), that is present in almost every vertebrate animal cell.

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Health system

A health system, also sometimes referred to as health care system or healthcare system, is the organization of people, institutions, and resources that deliver health care services to meet the health needs of target populations.

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Hirsutism is the excessive hairiness on women in those parts of the body where terminal hair does not normally occur or is minimal — for example, a beard or chest hair.

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Hypertension (HTN or HT), also known as high blood pressure or arterial hypertension, is a chronic medical condition in which the blood pressure in the arteries is persistently elevated.

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Hypokalemia (American English) or hypokalaemia (British English), also hypopotassemia or hypopotassaemia (ICD-9), refers to the condition in which the concentration of potassium (K+) in the blood is low.

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Indigestion, also known as dyspepsia, is a condition of impaired digestion.

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Insomnia, or trouble sleeping, is a sleep disorder in which there is an inability to fall asleep or to stay asleep as long as desired.

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Intracranial pressure

Intracranial pressure (ICP) is the pressure inside the skull and thus in the brain tissue and cerebrospinal fluid (CSF).

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Mineralocorticoid(s) are a class of steroid hormones characterized by their influence on salt and water balances.

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Orthostatic intolerance

Orthostatic intolerance (OI) is the development of symptoms when standing upright which are relieved when reclining.

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Peptic ulcer

Peptic ulcer disease (PUD), also known as a peptic ulcer or stomach ulcer, is a break in the lining of the stomach, first part of the small intestine, or occasionally the lower esophagus.

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Postural orthostatic tachycardia syndrome

Postural orthostatic tachycardia syndrome (POTS, also known as postural tachycardia syndrome) is a condition in which a change from the supine position to an upright position causes an abnormally large increase in heart rate, called tachycardia.

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Primary aldosteronism

Primary aldosteronism, also known as primary hyperaldosteronism or Conn's syndrome, is excess production of the hormone aldosterone by the adrenal glands resulting in low renin levels.

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WHO Model List of Essential Medicines

WHO Model List of Essential Medicines is published by the World Health Organization (WHO).

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Redirects here:

9 .Alpha. Ff, 9 Alpha Ff, 9 alpha-Fludrocortisone, 9 alpha-Fluorocortisol, 9.Alpha.-Fluorocortisol, 9α-Flouocortisol, ATC code H02AA02, ATCvet code QH02AA02, Alflorone, Astonin-H, C21H29FO5, F-COL, F-Cortef, Florinef, Fludrocortisone acetate, Fludrocortone, Fludrone, Fludronef, Fluodrocortisone, Fluohydrisone, Fluohydrocortisone, Fluorocortisol, Fluorocortisone, ZK5.


[1] https://en.wikipedia.org/wiki/Fludrocortisone

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