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Fludrocortisone

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Fludrocortisone, sold under the brand name Florinef among others, is a corticosteroid which is used to treat adrenogenital syndrome, postural hypotension, and adrenal insufficiency. [1]

65 relations: Acetate, Addison's disease, Adrenal insufficiency, Aldosterone, Australia, Austria, Bioisostere, Brazil, Canada, Cataract, Cerebral salt-wasting syndrome, China, Congenital adrenal hyperplasia, Congenital adrenal hyperplasia due to 21-hydroxylase deficiency, Corticosteroid, Cortisol, Cortisone, Croatia, Denmark, Derivative (chemistry), Edema, Electronegativity, Ester, Europe, Fluorine, Germany, Glaucoma, Glucocorticoid, Halogen, Health system, Heart failure, Hirsutism, Hydrocortisone, Hydrogen, Hydrolysis, Hypertension, Hypokalemia, Immunosuppression, Indigestion, Insomnia, Intracranial pressure, Japan, Liver, Luxembourg, Mineralocorticoid, National Health Service, Oral administration, Organic compound, Orthostatic hypotension, Orthostatic intolerance, ..., Peptic ulcer disease, Postural orthostatic tachycardia syndrome, Potency (pharmacology), Pregnancy, Pregnane, Primary aldosteronism, Prodrug, Romania, Spain, Steroid, Substituent, Trademark distinctiveness, United Kingdom, United States, WHO Model List of Essential Medicines. Expand index (15 more) »

Acetate

An acetate is a salt formed by the combination of acetic acid with an alkaline, earthy, metallic or nonmetallic and other base.

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Addison's disease

Addison's disease, also known as primary adrenal insufficiency and hypocortisolism, is a long-term endocrine disorder in which the adrenal glands do not produce enough steroid hormones.

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Adrenal insufficiency

Adrenal insufficiency is a condition in which the adrenal glands do not produce adequate amounts of steroid hormones, primarily cortisol; but may also include impaired production of aldosterone (a mineralocorticoid), which regulates sodium conservation, potassium secretion, and water retention.

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Aldosterone

Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.

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Australia

Australia, officially the Commonwealth of Australia, is a sovereign country comprising the mainland of the Australian continent, the island of Tasmania and numerous smaller islands.

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Austria

Austria (Österreich), officially the Republic of Austria (Republik Österreich), is a federal republic and a landlocked country of over 8.8 million people in Central Europe.

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Bioisostere

In medicinal chemistry, bioisosteres are chemical substituents or groups with similar physical or chemical properties which produce broadly similar biological properties to another chemical compound.

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Brazil

Brazil (Brasil), officially the Federative Republic of Brazil (República Federativa do Brasil), is the largest country in both South America and Latin America.

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Canada

Canada is a country located in the northern part of North America.

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Cataract

A cataract is a clouding of the lens in the eye which leads to a decrease in vision.

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Cerebral salt-wasting syndrome

Cerebral salt-wasting syndrome (CSWS) is a rare endocrine condition featuring a low blood sodium concentration and dehydration in response to injury (trauma) or the presence of tumors in or surrounding the brain.

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China

China, officially the People's Republic of China (PRC), is a unitary one-party sovereign state in East Asia and the world's most populous country, with a population of around /1e9 round 3 billion.

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Congenital adrenal hyperplasia

Congenital adrenal hyperplasia (CAH) are any of several autosomal recessive diseases resulting from mutations of genes for enzymes mediating the biochemical steps of production of mineralocorticoids, glucocorticoids or sex steroids from cholesterol by the adrenal glands (steroidogenesis).

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Congenital adrenal hyperplasia due to 21-hydroxylase deficiency

Congenital adrenal hyperplasia due to 21-hydroxylase deficiency (21-OH CAH), in all its forms, accounts for over 95% of diagnosed cases of congenital adrenal hyperplasia, and "CAH" in most contexts refers to 21-hydroxylase deficiency.

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Corticosteroid

Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.

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Cortisol

Cortisol is a steroid hormone, in the glucocorticoid class of hormones.

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Cortisone

Cortisone, also known as 17α,21-dihydroxypregn-4-ene-3,11,20-trione, is a pregnane (21-carbon) steroid hormone.

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Croatia

Croatia (Hrvatska), officially the Republic of Croatia (Republika Hrvatska), is a country at the crossroads of Central and Southeast Europe, on the Adriatic Sea.

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Denmark

Denmark (Danmark), officially the Kingdom of Denmark,Kongeriget Danmark,.

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Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

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Edema

Edema, also spelled oedema or œdema, is an abnormal accumulation of fluid in the interstitium, located beneath the skin and in the cavities of the body, which can cause severe pain.

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Electronegativity

Electronegativity, symbol ''χ'', is a chemical property that describes the tendency of an atom to attract a shared pair of electrons (or electron density) towards itself.

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Ester

In chemistry, an ester is a chemical compound derived from an acid (organic or inorganic) in which at least one –OH (hydroxyl) group is replaced by an –O–alkyl (alkoxy) group.

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Europe

Europe is a continent located entirely in the Northern Hemisphere and mostly in the Eastern Hemisphere.

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Fluorine

Fluorine is a chemical element with symbol F and atomic number 9.

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Germany

Germany (Deutschland), officially the Federal Republic of Germany (Bundesrepublik Deutschland), is a sovereign state in central-western Europe.

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Glaucoma

Glaucoma is a group of eye diseases which result in damage to the optic nerve and vision loss.

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Glucocorticoid

Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones.

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Halogen

The halogens are a group in the periodic table consisting of five chemically related elements: fluorine (F), chlorine (Cl), bromine (Br), iodine (I), and astatine (At).

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Health system

A health system, also sometimes referred to as health care system or as healthcare system, is the organization of people, institutions, and resources that deliver health care services to meet the health needs of target populations.

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Heart failure

Heart failure (HF), often referred to as congestive heart failure (CHF), is when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs.

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Hirsutism

Hirsutism is excessive body hair in men and women on parts of the body where hair is normally absent or minimal, such as on the chin or chest in particular, or the face or body in general.

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Hydrocortisone

Hydrocortisone, sold under a number of brand names, is the name for the hormone cortisol when supplied as a medication.

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Hydrogen

Hydrogen is a chemical element with symbol H and atomic number 1.

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Hydrolysis

Hydrolysis is a term used for both an electro-chemical process and a biological one.

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Hypertension

Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.

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Hypokalemia

Hypokalemia, also spelled hypokalaemia, is a low level of potassium (K+) in the blood serum.

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Immunosuppression

Immunosuppression is a reduction of the activation or efficacy of the immune system.

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Indigestion

Indigestion, also known as dyspepsia, is a condition of impaired digestion.

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Insomnia

Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping.

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Intracranial pressure

Intracranial pressure (ICP) is the pressure inside the skull and thus in the brain tissue and cerebrospinal fluid (CSF).

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Japan

Japan (日本; Nippon or Nihon; formally 日本国 or Nihon-koku, lit. "State of Japan") is a sovereign island country in East Asia.

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Liver

The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.

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Luxembourg

Luxembourg (Lëtzebuerg; Luxembourg, Luxemburg), officially the Grand Duchy of Luxembourg, is a landlocked country in western Europe.

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Mineralocorticoid

Mineralocorticoids are a class of corticosteroids, which in turn are a class of steroid hormones.

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National Health Service

The National Health Service (NHS) is the name used for each of the public health services in the United Kingdom – the National Health Service in England, NHS Scotland, NHS Wales, and Health and Social Care in Northern Ireland – as well as a term to describe them collectively.

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Oral administration

| name.

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Organic compound

In chemistry, an organic compound is generally any chemical compound that contains carbon.

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Orthostatic hypotension

Orthostatic hypotension, also known as postural hypotension, occurs when a person's blood pressure falls when suddenly standing up from a lying or sitting position.

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Orthostatic intolerance

Orthostatic intolerance (OI) is the development of symptoms when standing upright which are relieved when reclining.

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Peptic ulcer disease

Peptic ulcer disease (PUD) is a break in the lining of the stomach, first part of the small intestine or occasionally the lower esophagus.

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Postural orthostatic tachycardia syndrome

Postural orthostatic tachycardia syndrome (POTS) is a condition in which a change from lying to standing causes an abnormally large increase in heart rate.

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Potency (pharmacology)

In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.

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Pregnancy

Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.

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Pregnane

Pregnane is a C21 steroid and, indirectly, a parent of progesterone.

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Primary aldosteronism

Primary aldosteronism, also known as primary hyperaldosteronism or Conn's syndrome, refers to the excess production of the hormone aldosterone from the adrenal glands, resulting in low renin levels.

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Prodrug

A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug.

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Romania

Romania (România) is a sovereign state located at the crossroads of Central, Eastern, and Southeastern Europe.

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Spain

Spain (España), officially the Kingdom of Spain (Reino de España), is a sovereign state mostly located on the Iberian Peninsula in Europe.

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Steroid

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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Substituent

In organic chemistry and biochemistry, a substituent is an atom or group of atoms which replaces one or more hydrogen atoms on the parent chain of a hydrocarbon, becoming a moiety of the resultant new molecule.

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Trademark distinctiveness

Trademark distinctiveness is an important concept in the law governing trademarks and service marks.

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United Kingdom

The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain,Usage is mixed with some organisations, including the and preferring to use Britain as shorthand for Great Britain is a sovereign country in western Europe.

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United States

The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.

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WHO Model List of Essential Medicines

The WHO Model List of Essential Medicines (EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system.

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Redirects here:

9 .Alpha. Ff, 9 Alpha Ff, 9 alpha-Fludrocortisone, 9 alpha-Fluorocortisol, 9.Alpha.-Fluorocortisol, 9α-Flouocortisol, ATC code H02AA02, ATCvet code QH02AA02, Alflorone, Astonin-H, C21H29FO5, Cortinef, Cortineff, F-COL, F-Cortef, Florinef, Florinefe, Fludrocortison, Fludrocortisone 21-acetate, Fludrocortisone acetate, Fludrocortone, Fludrone, Fludronef, Fluodrocortisone, Fluohydrisone, Fluohydrocortisone, Fluorocortisol, Fluorohydrocortisone acetate, ZK5.

References

[1] https://en.wikipedia.org/wiki/Fludrocortisone

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