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163 relations: Absorption (pharmacology), Acinar cell carcinoma of the pancreas, Active transport, Addiction, Adenocarcinoma, Aggression, Alcohol abuse, Alcohol withdrawal syndrome, Amine, Amino acid, Analgesic, Annals of Internal Medicine, Anticonvulsant, Anxiety disorder, Anxiolytic, Area under the curve (pharmacokinetics), Atagabalin, Ataxia, Binding selectivity, Bioavailability, Biological activity, Biological half-life, Bipolar disorder, Blood–brain barrier, Bloomberg News, Boxed warning, Brain, Breastfeeding, CACNA2D1, CACNA2D2, Calcium channel, Cancer, CD98, Central nervous system, Central pain syndrome, Cerebrospinal fluid, Channel blocker, Chemical structure, Chemical synthesis, Cmax (pharmacology), Cochrane (organisation), Competitive inhibition, Complex regional pain syndrome, Cyclohexane, David Franklin (scientist), Derivative (chemistry), Developing country, Diabetic neuropathy, Dizziness, Drug prohibition law, ..., Drug reaction with eosinophilia and systemic symptoms, Drug tolerance, Drug withdrawal, Elimination (pharmacology), Endogeny (biology), Enzyme, Epilepsy, Epileptic seizure, Erectile dysfunction, Essential tremor, Esterase, Fatigue, Focal seizure, Food and Drug Administration, GABA analogue, GABA receptor, GABA receptor agonist, Gabapentin enacarbil, Gabapentinoid, Gastrointestinal tract, Generalized epilepsy, Generic drug, Headache (journal), Hot flash, Hydrolysis, Hydroxy group, IC50, In vivo, Insomnia, Isoleucine, Kentucky, Kidney, Kidney disease, Kidney failure, Knee replacement, Leucine, Libido, Ligand (biochemistry), Lipophilicity, List of largest pharmaceutical settlements, List of off-label promotion pharmaceutical settlements, Liver, Low back pain, Medical guideline, Medicine, Metabolism, Metastasis, Modified-release dosage, Molar concentration, Monocarboxylate transporter 1, Mood stabilizer, Morphine, Multiple sclerosis, Neuropathic pain, Neurotransmitter, Neurotransmitter transporter, Nortriptyline, Nystagmus, Obsessive–compulsive disorder, Off-label use, Opioid, Oral administration, Orgasm, Oxycodone, P-glycoprotein, Parke-Davis, Peripheral edema, Peristalsis, Pfizer, Pharmacodynamics, Pharmacokinetics, Phenylalanine, Plasma protein binding, PLOS One, Postherpetic neuralgia, Pregabalin, Pregnancy, Prodrug, Recreational drug use, Renal function, Restless legs syndrome, Reuters, Ring (chemistry), Saturation (chemistry), Seizure types, Sexual dysfunction, Shingles, Side effect, SLC22A5, SLC5A6, Small intestine, Smoking cessation, Somnolence, Structural analog, Substance abuse, Substituent, Suicide, Teva Pharmaceutical Industries, The New England Journal of Medicine, The New York Times, The Wall Street Journal, Tinnitus, Treatment-resistant depression, Tremor, United Kingdom, United States, United States Department of Justice, Uremic pruritus, Urine, Venlafaxine, Voltage-gated calcium channel, Warner–Lambert, Xylitol. Expand index (113 more) »
Absorption (pharmacology)
In pharmacology (and more specifically pharmacokinetics), absorption is the movement of a drug from the site of administration to bloodstream.
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Acinar cell carcinoma of the pancreas
Acinar cell carcinoma of the pancreas, also acinar cell carcinoma, is a rare malignant exocrine tumour of the pancreas.
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Active transport
Active transport is the movement of molecules across a membrane from a region of their lower concentration to a region of their higher concentration—in the direction against the concentration gradient.
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Addiction
Addiction is a brain disorder characterized by compulsive engagement in rewarding stimuli despite adverse consequences.
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Adenocarcinoma
Adenocarcinoma (plural adenocarcinomas or adenocarcinomata) is a type of cancerous tumor that can occur in several parts of the body.
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Aggression
Aggression is overt, often harmful, social interaction with the intention of inflicting damage or other unpleasantness upon another individual.
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Alcohol abuse
Alcohol abuse is a previous psychiatric diagnosis in which there is recurring harmful use of alcohol despite its negative consequences.
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Alcohol withdrawal syndrome
Alcohol withdrawal syndrome is a set of symptoms that can occur following a reduction in alcohol use after a period of excessive use.
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Amine
In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair.
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Amino acid
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
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Analgesic
An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.
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Annals of Internal Medicine
Annals of Internal Medicine is an academic medical journal published by the American College of Physicians (ACP).
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Anticonvulsant
Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.
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Anxiety disorder
Anxiety disorders are a group of mental disorders characterized by significant feelings of anxiety and fear.
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Anxiolytic
An anxiolytic (also antipanic or antianxiety agent) is a medication or other intervention that inhibits anxiety.
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Area under the curve (pharmacokinetics)
In the field of pharmacokinetics, the area under the curve (AUC) is the definite integral in a plot of drug concentration in blood plasma vs.
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Atagabalin
Atagabalin (PD-0200,390) is a drug developed by Pfizer and related to gabapentin, which similarly binds to the α2δ calcium channels (1 and 2).
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Ataxia
Ataxia is a neurological sign consisting of lack of voluntary coordination of muscle movements that includes gait abnormality.
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Binding selectivity
Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.
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Bioavailability
In pharmacology, bioavailability (BA or F) is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.
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Biological activity
In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter.
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Biological half-life
The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.
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Bipolar disorder
Bipolar disorder, previously known as manic depression, is a mental disorder that causes periods of depression and periods of abnormally elevated mood.
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Blood–brain barrier
The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).
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Bloomberg News
Bloomberg News is an international news agency headquartered in New York, United States and a division of Bloomberg L.P. Content produced by Bloomberg News is disseminated through Bloomberg Terminals, Bloomberg Television, Bloomberg Radio, Bloomberg Businessweek, Bloomberg Markets, Bloomberg.com and Bloomberg's mobile platforms.
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Boxed warning
In the United States, a boxed warning (sometimes "black box warning", colloquially) is a type of warning that appears on the package insert for certain prescription drugs, so called because the U.S. Food and Drug Administration specifies that it is formatted with a 'box' or border around the text.
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Brain
The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.
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Breastfeeding
Breastfeeding, also known as nursing, is the feeding of babies and young children with milk from a woman's breast.
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CACNA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1 is a protein that in humans is encoded by the CACNA2D1 gene.
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CACNA2D2
Voltage-dependent calcium channel subunit alpha2delta-2 is a protein that in humans is encoded by the CACNA2D2 gene.
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Calcium channel
A calcium channel is an ion channel which shows selective permeability to calcium ions.
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
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CD98
CD98 is a glycoprotein that is a heterodimer composed of SLC3A2 and SLC7A5 that forms the large neutral amino acid transporter (LAT1).
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Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
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Central pain syndrome
Central pain syndrome is a neurological condition caused by damage or malfunction in the Central Nervous System (CNS) which causes a sensitization of the pain system.
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Cerebrospinal fluid
Cerebrospinal fluid (CSF) is a clear, colorless body fluid found in the brain and spinal cord.
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Channel blocker
A channel blocker is the biological mechanism in which a particular molecule is used to prevent the opening of ion channels in order to produce a physiological response in a cell.
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Chemical structure
A chemical structure determination includes a chemist's specifying the molecular geometry and, when feasible and necessary, the electronic structure of the target molecule or other solid.
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Chemical synthesis
Chemical synthesis is a purposeful execution of chemical reactions to obtain a product, or several products.
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Cmax (pharmacology)
Cmax is the maximum (or peak) serum concentration that a drug achieves in a specified compartment or test area of the body after the drug has been administrated and before the administration of a second dose.
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Cochrane (organisation)
Cochrane is a non-profit, non-governmental organization formed to organize medical research findings so as to facilitate evidence-based choices about health interventions faced by health professionals, patients, and policy makers.
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Competitive inhibition
Competitive inhibition is a form of enzyme inhibition where binding of an inhibitor prevents binding of the target molecule of the enzyme, also known as the substrate.
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Complex regional pain syndrome
Complex regional pain syndrome (CRPS), also known as reflex sympathetic dystrophy (RSD) or algodystrophy, is a disorder of a portion of the body, usually the arms or legs, which manifests as pain, swelling, limited range of motion, and changes to the skin and bones.
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Cyclohexane
Cyclohexane is a cycloalkane with the molecular formula C6H12 (the alkyl is abbreviated Cy).
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David Franklin (scientist)
David Franklin is an American microbiologist and former fellow of Harvard Medical School who while employed by Parke-Davis filed the 1996 whistleblower lawsuit exposing their illegal promotion of Neurontin (gabapentin) for off-label uses.
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Derivative (chemistry)
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.
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Developing country
A developing country (or a low and middle income country (LMIC), less developed country, less economically developed country (LEDC), underdeveloped country) is a country with a less developed industrial base and a low Human Development Index (HDI) relative to other countries.
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Diabetic neuropathy
Diabetic neuropathies are nerve damaging disorders associated with diabetes mellitus.
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Dizziness
Dizziness is an impairment in spatial perception and stability.
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Drug prohibition law
Drug prohibition law is prohibition-based law by which governments prohibit, except under licence, the production, supply, and possession of many, but not all, substances which are recognized as drugs, and which corresponds to international treaty commitments in the Single Convention on Narcotic Drugs 1961, the Convention on Psychotropic Substances 1971, and the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances 1988.
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Drug reaction with eosinophilia and systemic symptoms
Drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), also termed drug-induced hypersensitivity syndrome (DIHS), is a rare reaction to certain medications.
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Drug tolerance
Drug tolerance is a pharmacological concept describing subjects' reduced reaction to a drug following its repeated use.
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Drug withdrawal
Drug withdrawal is the group of symptoms that occur upon the abrupt discontinuation or decrease in intake of medications or recreational drugs.
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Elimination (pharmacology)
In pharmacology the elimination or excretion of a drug is understood to be any one of a number of processes by which a drug is eliminated (that is, cleared and excreted) from an organism either in an unaltered form (unbound molecules) or modified as a metabolite.
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Endogeny (biology)
Endogenous substances and processes are those that originate from within an organism, tissue, or cell.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Epilepsy
Epilepsy is a group of neurological disorders characterized by epileptic seizures.
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Epileptic seizure
An epileptic seizure is a brief episode of signs or symptoms due to abnormally excessive or synchronous neuronal activity in the brain.
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Erectile dysfunction
Erectile dysfunction (ED), also known as impotence, is a type of sexual dysfunction characterized by the inability to develop or maintain an erection of the penis during sexual activity.
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Essential tremor
Essential tremor (ET, also referred to as benign tremor, familial tremor, or idiopathic tremor) is a progressive neurological disorder that is also the most common movement disorder.
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Esterase
An esterase is a hydrolase enzyme that splits esters into an acid and an alcohol in a chemical reaction with water called hydrolysis.
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Fatigue
Fatigue is a subjective feeling of tiredness that has a gradual onset.
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Focal seizure
Focal seizures (also called partial seizures and localized seizures) are seizures which affect initially only one hemisphere of the brain.
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Food and Drug Administration
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
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GABA analogue
A GABA analogue is a compound which is an analogue or derivative of the neurotransmitter gamma-Aminobutyric acid (GABA) (the IUPAC of which is 4-aminobutanoic acid).
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GABA receptor
The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the mature vertebrate central nervous system.
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GABA receptor agonist
A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects.
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Gabapentin enacarbil
Gabapentin enacarbil (Horizant, Regnite (in Japan)) is an anticonvulsant and analgesic drug of the gabapentinoid class, and a prodrug to gabapentin.
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Gabapentinoid
Gabapentinoids, also known as α2δ ligands, are a class of drugs that are derivatives of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) (i.e., GABA analogues) which block α2δ subunit-containing voltage-dependent calcium channels (VDCCs).
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Gastrointestinal tract
The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.
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Generalized epilepsy
Generalized epilepsy, also known as primary generalized epilepsy or idiopathic epilepsy, is a form of epilepsy characterised by generalised seizures with no apparent cause.
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Generic drug
A generic drug is a pharmaceutical drug that is equivalent to a brand-name product in dosage, strength, route of administration, quality, performance, and intended use, but does not carry the brand name.
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Headache (journal)
Headache: The Journal of Head and Face Pain is a peer-reviewed medical journal covering all aspects of head and face pain.
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Hot flash
Hot flashes (American English) or hot flushes (British English) are a form of flushing due to reduced levels of estradiol.
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Hydrolysis
Hydrolysis is a term used for both an electro-chemical process and a biological one.
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Hydroxy group
A hydroxy or hydroxyl group is the entity with the formula OH.
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IC50
The half maximal inhibitory concentration (IC50) is a measure of the potency of a substance in inhibiting a specific biological or biochemical function.
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In vivo
Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.
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Insomnia
Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping.
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Isoleucine
Isoleucine (symbol Ile or I) is an α-amino acid that is used in the biosynthesis of proteins.
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Kentucky
Kentucky, officially the Commonwealth of Kentucky, is a state located in the east south-central region of the United States.
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Kidney
The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.
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Kidney disease
Kidney disease, or renal disease, also known as nephropathy, is damage to or disease of a kidney.
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Kidney failure
Kidney failure, also known as end-stage kidney disease, is a medical condition in which the kidneys no longer work.
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Knee replacement
Knee replacement, also known as knee arthroplasty, is a surgical procedure to replace the weight-bearing surfaces of the knee joint to relieve pain and disability.
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Leucine
Leucine (symbol Leu or L) is an essential amino acid that is used in the biosynthesis of proteins.
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Libido
Libido, colloquially known as sex drive, is a person's overall sexual drive or desire for sexual activity.
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Ligand (biochemistry)
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
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Lipophilicity
Lipophilicity (from Greek λίπος "fat" and φίλος "friendly"), refers to the ability of a chemical compound to dissolve in fats, oils, lipids, and non-polar solvents such as hexane or toluene.
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List of largest pharmaceutical settlements
The following is a list of the 20 largest settlements reached between the United States Department of Justice and pharmaceutical companies from 1991 to 2012, ordered by the size of the total settlement.
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List of off-label promotion pharmaceutical settlements
The following are settlements reached with US authorities against pharmaceutical companies to resolve allegations of "off-label" promotion of drugs.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Low back pain
Low back pain (LBP) is a common disorder involving the muscles, nerves, and bones of the back.
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Medical guideline
A medical guideline (also called a clinical guideline or clinical practice line) is a document with the aim of guiding decisions and criteria regarding diagnosis, management, and treatment in specific areas of healthcare.
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Medicine
Medicine is the science and practice of the diagnosis, treatment, and prevention of disease.
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Metabolism
Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.
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Metastasis
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.
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Modified-release dosage
Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release dosage) or to a specific target in the body (targeted-release dosage).
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Molar concentration
Molar concentration (also called molarity, amount concentration or substance concentration) is a measure of the concentration of a chemical species, in particular of a solute in a solution, in terms of amount of substance per unit volume of solution.
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Monocarboxylate transporter 1
Monocarboxylate transporter 1 is a protein that in humans is encoded by the SLC16A1 gene (also known as MCT1).
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Mood stabilizer
A mood stabilizer is a psychiatric pharmaceutical drug used to treat mood disorders characterized by intense and sustained mood shifts, typically bipolar disorder type I or type II, borderline personality disorder (BPD) and schizophrenia.
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Morphine
Morphine is a pain medication of the opiate variety which is found naturally in a number of plants and animals.
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Multiple sclerosis
Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.
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Neuropathic pain
Neuropathic pain is pain caused by damage or disease affecting the somatosensory nervous system.
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Neurotransmitter
Neurotransmitters are endogenous chemicals that enable neurotransmission.
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Neurotransmitter transporter
Neurotransmitter transporters are a class of membrane transport proteins that span the cellular membranes of neurons.
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Nortriptyline
Nortriptyline, sold under the brand names Allegron, Aventyl, Noritren, Nortrilen, and Pamelor among others, is a tricyclic antidepressant (TCA) used to treat clinical depression.
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Nystagmus
Nystagmus is a condition of involuntary (or voluntary, in rare cases) eye movement, acquired in infancy or later in life, that may result in reduced or limited vision.
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Obsessive–compulsive disorder
Obsessive–compulsive disorder (OCD) is a mental disorder where people feel the need to check things repeatedly, perform certain routines repeatedly (called "rituals"), or have certain thoughts repeatedly (called "obsessions").
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Off-label use
Off-label use is the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration.
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Opioid
Opioids are substances that act on opioid receptors to produce morphine-like effects.
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Oral administration
| name.
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Orgasm
Orgasm (from Greek ὀργασμός orgasmos "excitement, swelling"; also sexual climax) is the sudden discharge of accumulated sexual excitement during the sexual response cycle, resulting in rhythmic muscular contractions in the pelvic region characterized by sexual pleasure.
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Oxycodone
Oxycodone, sold under brand names such as Percocet and OxyContin among many others, is an opioid medication which is used for the relief of moderate to severe pain.
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P-glycoprotein
P-glycoprotein 1 (permeability glycoprotein, abbreviated as P-gp or Pgp) also known as multidrug resistance protein 1 (MDR1) or ATP-binding cassette sub-family B member 1 (ABCB1) or cluster of differentiation 243 (CD243) is an important protein of the cell membrane that pumps many foreign substances out of cells.
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Parke-Davis
Parke-Davis is a subsidiary of the pharmaceutical company Pfizer.
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Peripheral edema
Peripheral edema is edema (accumulation of fluid causing swelling) in tissues perfused by the peripheral vascular system, usually in the lower limbs.
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Peristalsis
Peristalsis is a radially symmetrical contraction and relaxation of muscles that propagates in a wave down a tube, in an anterograde direction.
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Pfizer
Pfizer Inc. is an American pharmaceutical conglomerate headquartered in New York City, with its research headquarters in Groton, Connecticut.
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Pharmacodynamics
Pharmacodynamics is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).
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Pharmacokinetics
Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism.
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Phenylalanine
Phenylalanine (symbol Phe or F) is an α-amino acid with the formula.
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Plasma protein binding
Plasma protein binding refers to the degree to which medications attach to proteins within the blood.
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PLOS One
PLOS One (stylized PLOS ONE, and formerly PLoS ONE) is a peer-reviewed open access scientific journal published by the Public Library of Science (PLOS) since 2006.
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Postherpetic neuralgia
Postherpetic neuralgia (PHN) is nerve pain which occurs due to damage to a peripheral nerve caused by the reactivation of the varicella zoster virus (herpes zoster, also known as shingles).
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Pregabalin
Pregabalin, marketed under the brand name Lyrica among others, is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder.
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Pregnancy
Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.
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Prodrug
A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug.
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Recreational drug use
Recreational drug use is the use of a psychoactive drug to induce an altered state of consciousness for pleasure, by modifying the perceptions, feelings, and emotions of the user.
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Renal function
Renal function, in nephrology, is an indication of the kidney's condition and its role in renal physiology.
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Restless legs syndrome
Restless legs syndrome (RLS) is a disorder that causes a strong urge to move one's legs.
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Reuters
Reuters is an international news agency headquartered in London, United Kingdom.
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Ring (chemistry)
In chemistry, a ring is an ambiguous term referring either to a simple cycle of atoms and bonds in a molecule or to a connected set of atoms and bonds in which every atom and bond is a member of a cycle (also called a ring system).
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Saturation (chemistry)
In chemistry, saturation (from the Latin word saturare, meaning 'to fill') has diverse meanings, all based on the idea of reaching a maximum capacity.
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Seizure types
Seizure types most commonly follow the classification proposed by the International League Against Epilepsy (ILAE) in 1981.
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Sexual dysfunction
Sexual dysfunction (or sexual malfunction or sexual disorder) is difficulty experienced by an individual or a couple during any stage of a normal sexual activity, including physical pleasure, desire, preference, arousal or orgasm.
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Shingles
Shingles, also known as herpes zoster, is a viral disease characterized by a painful skin rash with blisters in a localized area.
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Side effect
In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.
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SLC22A5
SLC22A5 is a membrane transport protein associated with primary carnitine deficiency.
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SLC5A6
Sodium-dependent multivitamin transporter is a protein that in humans is encoded by the SLC5A6 gene.
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Small intestine
The small intestine or small bowel is the part of the gastrointestinal tract between the stomach and the large intestine, and is where most of the end absorption of food takes place.
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Smoking cessation
Smoking cessation (also known as quitting smoking or simply quitting) is the process of discontinuing tobacco smoking.
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Somnolence
Somnolence (alternatively "sleepiness" or "drowsiness") is a state of strong desire for sleep, or sleeping for unusually long periods (compare hypersomnia).
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Structural analog
A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.
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Substance abuse
Substance abuse, also known as drug abuse, is a patterned use of a drug in which the user consumes the substance in amounts or with methods which are harmful to themselves or others, and is a form of substance-related disorder.
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Substituent
In organic chemistry and biochemistry, a substituent is an atom or group of atoms which replaces one or more hydrogen atoms on the parent chain of a hydrocarbon, becoming a moiety of the resultant new molecule.
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Suicide
Suicide is the act of intentionally causing one's own death.
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Teva Pharmaceutical Industries
Teva Pharmaceutical Industries Ltd. (טבע תעשיות פרמצבטיות בע"מ) is an Israeli multinational pharmaceutical company headquartered in Petah Tikva, Israel.
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The New England Journal of Medicine
The New England Journal of Medicine (NEJM) is a weekly medical journal published by the Massachusetts Medical Society.
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The New York Times
The New York Times (sometimes abbreviated as The NYT or The Times) is an American newspaper based in New York City with worldwide influence and readership.
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The Wall Street Journal
The Wall Street Journal is a U.S. business-focused, English-language international daily newspaper based in New York City.
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Tinnitus
Tinnitus is the hearing of sound when no external sound is present.
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Treatment-resistant depression
Treatment-resistant depression (TRD) or treatment-refractory depression is a term used in clinical psychiatry to describe cases of major depressive disorder (MDD) that do not respond adequately to appropriate courses of at least two antidepressants.
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Tremor
A tremor is an involuntary, somewhat rhythmic, muscle contraction and relaxation involving oscillations or twitching movements of one or more body parts.
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United Kingdom
The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain,Usage is mixed with some organisations, including the and preferring to use Britain as shorthand for Great Britain is a sovereign country in western Europe.
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United States
The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.
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United States Department of Justice
The United States Department of Justice (DOJ), also known as the Justice Department, is a federal executive department of the U.S. government, responsible for the enforcement of the law and administration of justice in the United States, equivalent to the justice or interior ministries of other countries. The department was formed in 1870 during the Ulysses S. Grant administration. The Department of Justice administers several federal law enforcement agencies including the Federal Bureau of Investigation (FBI), and the Drug Enforcement Administration (DEA). The department is responsible for investigating instances of financial fraud, representing the United States government in legal matters (such as in cases before the Supreme Court), and running the federal prison system. The department is also responsible for reviewing the conduct of local law enforcement as directed by the Violent Crime Control and Law Enforcement Act of 1994. The department is headed by the United States Attorney General, who is nominated by the President and confirmed by the Senate and is a member of the Cabinet. The current Attorney General is Jeff Sessions.
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Uremic pruritus
Uremic pruritus (also known as uraemic pruritus or renal pruritus) is caused by chronic kidney failure and is the most common internal systemic cause of itching.
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Urine
Urine is a liquid by-product of metabolism in humans and in many animals.
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Venlafaxine
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant of the selective serotonin-norepinephrine reuptake inhibitor (SNRI) class.
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Voltage-gated calcium channel
Voltage-gated calcium channels (VGCCs), also known as voltage-dependent calcium channels (VDCCs), are a group of voltage-gated ion channels found in the membrane of excitable cells (e.g., muscle, glial cells, neurons, etc.) with a permeability to the calcium ion Ca2+.
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Warner–Lambert
Warner–Lambert was an American pharmaceutical company.
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Xylitol
Xylitol is a sugar alcohol used as a sweetener.
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Redirects here:
ATC code N03AX12, ATCvet code QN03AX12, Aclonium, C9H17NO2, Fanatrex, Gabacent, Gabaciz, Gabagamma, Gabalept, Gabantin, Gabapentin ER, Gabapentin XR, Gabapentin extended release, Gabapentin extended-release, Gabapentine, Gabapin, Gabatin, Gabatol, Gabator, Gabepentin, Gabex, Gabtin, Gaptin, Gralise, Neurontin, Neurotin, Novo-Gabapentin, Nurontin.
References
[1] https://en.wikipedia.org/wiki/Gabapentin
