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Gaboxadol

Index Gaboxadol

Gaboxadol, also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP), is a conformationally constrained derivative of the alkaloid muscimol that was first synthesized in 1977 by the Danish chemist Povl Krogsgaard-Larsen. [1]

20 relations: Adverse effect, Alkaloid, Alzheimer's disease, Amanita muscaria, Angelman syndrome, Barbiturate, Benzodiazepine, Chemist, CI-966, Fragile X syndrome, Gamma-Aminobutyric acid, Huntington's disease, Lundbeck, Merck & Co., Muscimol, Non-rapid eye movement sleep, Nonbenzodiazepine, Pilot experiment, Spasticity, Tardive dyskinesia.

Adverse effect

In medicine, an adverse effect is an undesired harmful effect resulting from a medication or other intervention such as surgery.

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Alkaloid

Alkaloids are a class of naturally occurring chemical compounds that mostly contain basic nitrogen atoms.

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Alzheimer's disease

Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time.

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Amanita muscaria

Amanita muscaria, commonly known as the fly agaric or fly amanita, is a basidiomycete mushroom, one of many in the genus Amanita.

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Angelman syndrome

Angelman syndrome (AS) is a genetic disorder that mainly affects the nervous system.

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Barbiturate

A barbiturate is a drug that acts as a central nervous system depressant, and can therefore produce a wide spectrum of effects, from mild sedation to death.

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Benzodiazepine

Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.

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Chemist

A chemist (from Greek chēm (ía) alchemy; replacing chymist from Medieval Latin alchimista) is a scientist trained in the study of chemistry.

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CI-966

CI-966 (developmental code name) is a central nervous system depressant acting as a GABA reuptake inhibitor, specifically a highly potent and selective blocker of the GABA transporter 1 (GAT-1) (IC50.

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Fragile X syndrome

Fragile X syndrome (FXS) is a genetic disorder.

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Gamma-Aminobutyric acid

gamma-Aminobutyric acid, or γ-aminobutyric acid, or GABA, is the chief inhibitory neurotransmitter in the mammalian central nervous system.

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Huntington's disease

Huntington's disease (HD), also known as Huntington's chorea, is an inherited disorder that results in death of brain cells.

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Lundbeck

H.

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Merck & Co.

Merck & Company, Inc., d.b.a. Merck Sharp & Dohme (MSD) outside the United States and Canada, is an American pharmaceutical company and one of the largest pharmaceutical companies in the world.

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Muscimol

Muscimol (also known as agarin or pantherine) is one of the principal psychoactive constituents of Amanita muscaria and related species of mushroom.

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Non-rapid eye movement sleep

Non-rapid eye movement sleep (NREM) is, collectively, sleep stages 1–3, previously known as stages 1–4.

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Nonbenzodiazepine

Nonbenzodiazepines (sometimes referred to colloquially as "Z-drugs") are a class of psychoactive drugs that are very benzodiazepine-like in nature.

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Pilot experiment

A pilot study, pilot project, or pilot experiment is a small scale preliminary study conducted in order to evaluate feasibility, time, cost, adverse events, and improve upon the study design prior to performance of a full-scale research project.

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Spasticity

Spasticity is a feature of altered skeletal muscle performance with a combination of paralysis, increased tendon reflex activity, and hypertonia.

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Tardive dyskinesia

Tardive dyskinesia (TD) is a disorder that results in involuntary, repetitive body movements.

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Redirects here:

THIP, Tetrahydroisoxazolopyridinol, Thip.

References

[1] https://en.wikipedia.org/wiki/Gaboxadol

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