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15 relations: Allosteric modulator, Anticonvulsant, Antidepressant, Anxiolytic, G protein–coupled receptor, Galanin, Galanin receptor 1, Galanin receptor 2, Galanin receptor 3, Galanin-like peptide, Galmic, Galnon, HT-2157, Metabotropic receptor, SCH-202,596.
Allosteric modulator
In biochemistry and pharmacology, an allosteric modulator (allo- from the Greek meaning "other") is a substance which indirectly influences (modulates) the effects of a primary ligand that directly activates or deactivates the function of a target protein.
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Anticonvulsant
Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.
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Antidepressant
Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.
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Anxiolytic
An anxiolytic (also antipanic or antianxiety agent) is a medication or other intervention that inhibits anxiety.
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G protein–coupled receptor
G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.
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Galanin
Galanin is a neuropeptide encoded by the GAL gene, that is widely expressed in the brain, spinal cord, and gut of humans as well as other mammals.
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Galanin receptor 1
Galanin receptor 1 (GAL1) is a G-protein coupled receptor encoded by the GALR1 gene.
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Galanin receptor 2
Galanin receptor 2, (GAL2) is a G-protein coupled receptor encoded by the GALR2 gene.
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Galanin receptor 3
Galanin receptor 3 (GAL3) is a G-protein coupled receptor encoded by the GALR3 gene.
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Galanin-like peptide
Galanin-like peptide (GALP) is a neuropeptide present in humans and other mammals.
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Galmic
Galmic is a drug which acts as a selective, non-peptide agonist at the galanin receptors GALR.
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Galnon
Galnon is a drug which acts as a selective, non-peptide agonist at the galanin receptors GALR.
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HT-2157
HT-2157 (former code name SNAP-37889) is a drug which acts as a selective non-peptide antagonist for the receptor GAL-3, which is usually activated by the neuropeptide galanin.
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Metabotropic receptor
A metabotropic receptor is a type of membrane receptor of eukaryotic cells that acts through a second messenger.
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SCH-202,596
SCH-202,596 is a natural product which is a metabolite derived from an Aspergillus fungus.
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