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Gene Disease Database

Index Gene Disease Database

In Bioinformatics, a Gene Disease Database is a systematized collection of data, typically structured to model aspects of reality, in a way to comprehend the underlying mechanisms of complex diseases, by understanding multiple composite interactions between phenotype-genotype relationships and gene-disease mechanisms. [1]

61 relations: Alzheimer's disease, Application programming interface, Biodiversity informatics, Bioinformatics, Biomedicine, BLAST, Cancer, Carcinoma, Chromosome, Clustal, Comparative Toxicogenomics Database, Computational biology, Computational genomics, Creative Commons, Database, Disease, Disease cluster, DisGeNET, DNA, Ensembl genome database project, European Bioinformatics Institute, FASTA, Functional genomics, General feature format, Genome, Genome-wide association study, Genomics, Genotype, Health informatics, Heredity, Human Genome Project, Integrative bioinformatics, International Society for Computational Biology, Java (programming language), Jumping library, List of bioinformatics companies, List of bioinformatics journals, List of biological databases, List of open-source bioinformatics software, Medical College of Wisconsin, Mendelian inheritance, Modelling biological systems, Molecular biology, Mutation, National Center for Biotechnology Information, Online Mendelian Inheritance in Man, Pathology, Phenotype, Phylogenetics, Protein, ..., Protein Information Resource, Proteomics, Rat Genome Database, Representational state transfer, Resource Description Framework, Single-nucleotide polymorphism, Structural bioinformatics, Swiss Institute of Bioinformatics, UniProt, Wellcome Sanger Institute, XML. Expand index (11 more) »

Alzheimer's disease

Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time.

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Application programming interface

In computer programming, an application programming interface (API) is a set of subroutine definitions, protocols, and tools for building software.

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Biodiversity informatics

Biodiversity Informatics is the application of informatics techniques to biodiversity information for improved management, presentation, discovery, exploration and analysis.

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Bioinformatics

Bioinformatics is an interdisciplinary field that develops methods and software tools for understanding biological data.

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Biomedicine

Biomedicine (i.e. medical biology) is a branch of medical science that applies biological and physiological principles to clinical practice.

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BLAST

In bioinformatics, BLAST for Basic Local Alignment Search Tool is an algorithm for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA sequences.

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Carcinoma

Carcinoma is a type of cancer that develops from epithelial cells.

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Chromosome

A chromosome (from Ancient Greek: χρωμόσωμα, chromosoma, chroma means colour, soma means body) is a DNA molecule with part or all of the genetic material (genome) of an organism.

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Clustal

Clustal is a series of widely used computer programs used in Bioinformatics for multiple sequence alignment.

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Comparative Toxicogenomics Database

The Comparative Toxicogenomics Database (CTD) is a public website and research tool launched in November 2004 that curates scientific data describing relationships between chemicals/drugs, genes/proteins, diseases, taxa, phenotypes, GO annotations, pathways, and interaction modules.

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Computational biology

Computational biology involves the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological, behavioral, and social systems.

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Computational genomics

Computational genomics (often referred to as Computational Genetics) refers to the use of computational and statistical analysis to decipher biology from genome sequences and related data, including both DNA and RNA sequence as well as other "post-genomic" data (i.e., experimental data obtained with technologies that require the genome sequence, such as genomic DNA microarrays).

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Creative Commons

Creative Commons (CC) is an American non-profit organization devoted to expanding the range of creative works available for others to build upon legally and to share.

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Database

A database is an organized collection of data, stored and accessed electronically.

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Disease

A disease is any condition which results in the disorder of a structure or function in an organism that is not due to any external injury.

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Disease cluster

A disease cluster is an unusually high incidence of a particular disease or disorder occurring in close proximity in terms of both time and geography.

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DisGeNET

DisGeNET is a discovery platform designed to address a variety of questions concerning the genetic underpinning of human diseases.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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Ensembl genome database project

Ensembl genome database project is a joint scientific project between the European Bioinformatics Institute and the Wellcome Trust Sanger Institute, which was launched in 1999 in response to the imminent completion of the Human Genome Project.

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European Bioinformatics Institute

The European Bioinformatics Institute (EMBL-EBI) is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory (EMBL).

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FASTA

FASTA is a DNA and protein sequence alignment software package first described by David J. Lipman and William R. Pearson in 1985.

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Functional genomics

Functional genomics is a field of molecular biology that attempts to make use of the vast wealth of data given by genomic and transcriptomic projects (such as genome sequencing projects and RNA sequencing) to describe gene (and protein) functions and interactions.

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General feature format

The general feature format (gene-finding format, generic feature format, GFF) is a file format used for describing genes and other features of DNA, RNA and protein sequences.

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Genome

In the fields of molecular biology and genetics, a genome is the genetic material of an organism.

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Genome-wide association study

In genetics, a genome-wide association study (GWA study, or GWAS), also known as whole genome association study (WGA study, or WGAS), is an observational study of a genome-wide set of genetic variants in different individuals to see if any variant is associated with a trait.

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Genomics

Genomics is an interdisciplinary field of science focusing on the structure, function, evolution, mapping, and editing of genomes.

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Genotype

The genotype is the part of the genetic makeup of a cell, and therefore of an organism or individual, which determines one of its characteristics (phenotype).

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Health informatics

Health informatics (also called health care informatics, healthcare informatics, medical informatics, nursing informatics, clinical informatics, or biomedical informatics) is information engineering applied to the field of health care, essentially the management and use of patient healthcare information.

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Heredity

Heredity is the passing on of traits from parents to their offspring, either through asexual reproduction or sexual reproduction, the offspring cells or organisms acquire the genetic information of their parents.

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Human Genome Project

The Human Genome Project (HGP) was an international scientific research project with the goal of determining the sequence of nucleotide base pairs that make up human DNA, and of identifying and mapping all of the genes of the human genome from both a physical and a functional standpoint.

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Integrative bioinformatics

Integrative bioinformatics is a discipline of bioinformatics that focuses on problems of data integration for the life sciences.

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International Society for Computational Biology

Founded in 1997, the International Society for Computational Biology (ISCB) is a scholarly society for researchers in computational biology and bioinformatics working towards advancing understanding of living systems through computation and for communicating scientific advances worldwide.

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Java (programming language)

Java is a general-purpose computer-programming language that is concurrent, class-based, object-oriented, and specifically designed to have as few implementation dependencies as possible.

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Jumping library

Jumping libraries or junction-fragment libraries are collections of genomic DNA fragments generated by chromosome jumping.

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List of bioinformatics companies

This is a list of bioinformatics companies that have articles at Wikipedia.

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List of bioinformatics journals

This is a list of articles about journals containing peer-reviewed scientific journals that focus on bioinformatics and computational biology.

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List of biological databases

Biological databases are stores of biological information.

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List of open-source bioinformatics software

This is a list of computer software which is made for bioinformatics and released under open-source software licenses with articles in Wikipedia.

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Medical College of Wisconsin

The Medical College of Wisconsin, or simply MCW, is a private, freestanding medical school and graduate school of sciences in the central United States, located in Milwaukee, Wisconsin.

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Mendelian inheritance

Mendelian inheritance is a type of biological inheritance that follows the laws originally proposed by Gregor Mendel in 1865 and 1866 and re-discovered in 1900.

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Modelling biological systems

Modelling biological systems is a significant task of systems biology and mathematical biology.

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Molecular biology

Molecular biology is a branch of biology which concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, proteins and their biosynthesis, as well as the regulation of these interactions.

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Mutation

In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.

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National Center for Biotechnology Information

The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health (NIH).

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Online Mendelian Inheritance in Man

Online Mendelian Inheritance in Man (OMIM) is a continuously updated catalog of human genes and genetic disorders and traits, with a particular focus on the gene-phenotype relationship.

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Pathology

Pathology (from the Ancient Greek roots of pathos (πάθος), meaning "experience" or "suffering" and -logia (-λογία), "study of") is a significant field in modern medical diagnosis and medical research, concerned mainly with the causal study of disease, whether caused by pathogens or non-infectious physiological disorder.

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Phenotype

A phenotype is the composite of an organism's observable characteristics or traits, such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior (such as a bird's nest).

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Phylogenetics

In biology, phylogenetics (Greek: φυλή, φῦλον – phylé, phylon.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein Information Resource

The Protein Information Resource (PIR), located at Georgetown University Medical Center (GUMC), is an integrated public bioinformatics resource to support genomic and proteomic research, and scientific studies.

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Proteomics

Proteomics is the large-scale study of proteins.

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Rat Genome Database

The Rat Genome Database (RGD) is the premiere location for rat genomics, genetics, physiology and functional data, as well as data for comparative genomics between rat, human and mouse.

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Representational state transfer

Representational State Transfer (REST) is an architectural style that defines a set of constraints and properties based on HTTP.

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Resource Description Framework

The Resource Description Framework (RDF) is a family of World Wide Web Consortium (W3C) specifications originally designed as a metadata data model.

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Single-nucleotide polymorphism

A single-nucleotide polymorphism, often abbreviated to SNP (plural), is a variation in a single nucleotide that occurs at a specific position in the genome, where each variation is present to some appreciable degree within a population (e.g. > 1%).

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Structural bioinformatics

Structural bioinformatics is the branch of bioinformatics which is related to the analysis and prediction of the three-dimensional structure of biological macromolecules such as proteins, RNA, and DNA.

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Swiss Institute of Bioinformatics

The SIB Swiss Institute of Bioinformatics is an academic not-for-profit foundation which federates bioinformatics activities throughout Switzerland.

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UniProt

UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects.

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Wellcome Sanger Institute

The Wellcome Sanger Institute, previously known as The Sanger Centre and Wellcome Trust Sanger Institute, is a non-profit British genomics and genetics research institute, primarily funded by the Wellcome Trust.

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XML

In computing, Extensible Markup Language (XML) is a markup language that defines a set of rules for encoding documents in a format that is both human-readable and machine-readable.

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References

[1] https://en.wikipedia.org/wiki/Gene_Disease_Database

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