Glycoprotein IIb/IIIa

In biochemistry and medicine, glycoprotein IIb/IIIa (GPIIb/IIIa, also known as integrin αIIbβ3) is an integrin complex found on platelets. ^[1]

25 relations: Abciximab, Adenosine diphosphate, Autocrine signaling, Biochemistry, Clopidogrel, Coagulation, Eptifibatide, Factor XIII, Fibrinogen, Glanzmann's thrombasthenia, Glycoprotein IIb/IIIa inhibitors, Immune thrombocytopenic purpura, Integrin, Integrin alpha 2b, Integrin beta 3, Medicine, Myocardial infarction, Paracrine signaling, Platelet, Protein kinase C, Stroke, Thrombin, Thromboxane A2, Tirofiban, Von Willebrand factor.
Integrins

Abciximab

Abciximab, a glycoprotein IIb/IIIa receptor antagonist manufactured by Janssen Biologics BV and distributed by Eli Lilly under the trade name ReoPro, is a platelet aggregation inhibitor mainly used during and after coronary artery procedures like angioplasty to prevent platelets from sticking together and causing thrombus (blood clot) formation within the coronary artery.

See Glycoprotein IIb/IIIa and Abciximab

Adenosine diphosphate

Adenosine diphosphate (ADP), also known as adenosine pyrophosphate (APP), is an important organic compound in metabolism and is essential to the flow of energy in living cells.

See Glycoprotein IIb/IIIa and Adenosine diphosphate

Autocrine signaling

Autocrine signaling is a form of cell signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent) that binds to autocrine receptors on that same cell, leading to changes in the cell.

See Glycoprotein IIb/IIIa and Autocrine signaling

Biochemistry

Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms.

See Glycoprotein IIb/IIIa and Biochemistry

Clopidogrel

Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk.

See Glycoprotein IIb/IIIa and Clopidogrel

Coagulation

Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot.

See Glycoprotein IIb/IIIa and Coagulation

Eptifibatide

Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class.

See Glycoprotein IIb/IIIa and Eptifibatide

Factor XIII

Factor XIII, or fibrin stabilizing factor, is a plasma protein and zymogen.

See Glycoprotein IIb/IIIa and Factor XIII

Fibrinogen

Fibrinogen (coagulation factor I) is a glycoprotein complex, produced in the liver, that circulates in the blood of all vertebrates.

See Glycoprotein IIb/IIIa and Fibrinogen

Glanzmann's thrombasthenia

Glanzmann's thrombasthenia is an abnormality of the platelets.

See Glycoprotein IIb/IIIa and Glanzmann's thrombasthenia

Glycoprotein IIb/IIIa inhibitors

In medicine, glycoprotein IIb/IIIa inhibitors, also GpIIb/IIIa inhibitors, is a class of antiplatelet agents.

See Glycoprotein IIb/IIIa and Glycoprotein IIb/IIIa inhibitors

Immune thrombocytopenic purpura

Immune thrombocytopenic purpura (ITP), also known as idiopathic thrombocytopenic purpura or immune thrombocytopenia, is an autoimmune primary disorder of hemostasis characterized by a low platelet count in the absence of other causes.

See Glycoprotein IIb/IIIa and Immune thrombocytopenic purpura

Integrin

Integrins are transmembrane receptors that help cell-cell and cell-extracellular matrix (ECM) adhesion. Glycoprotein IIb/IIIa and Integrin are Integrins.

See Glycoprotein IIb/IIIa and Integrin

Integrin alpha 2b

Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. Glycoprotein IIb/IIIa and Integrin alpha 2b are genes on human chromosome 17 and Integrins.

See Glycoprotein IIb/IIIa and Integrin alpha 2b

Integrin beta 3

Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene. Glycoprotein IIb/IIIa and Integrin beta 3 are genes on human chromosome 17, human chromosome 17 gene stubs and Integrins.

See Glycoprotein IIb/IIIa and Integrin beta 3

Medicine

Medicine is the science and practice of caring for patients, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health.

See Glycoprotein IIb/IIIa and Medicine

Myocardial infarction

A myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction (tissue death) to the heart muscle.

See Glycoprotein IIb/IIIa and Myocardial infarction

Paracrine signaling

In cellular biology, paracrine signaling is a form of cell signaling, a type of cellular communication in which a cell produces a signal to induce changes in nearby cells, altering the behaviour of those cells.

See Glycoprotein IIb/IIIa and Paracrine signaling

Platelet

Platelets or thrombocytes are a blood component whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.

See Glycoprotein IIb/IIIa and Platelet

Protein kinase C

In cell biology, Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family.

See Glycoprotein IIb/IIIa and Protein kinase C

Stroke

Stroke (also known as a cerebrovascular accident (CVA) or brain attack) is a medical condition in which poor blood flow to the brain causes cell death.

See Glycoprotein IIb/IIIa and Stroke

Thrombin

Prothrombin (Coagulation factor II) is encoded in the human by the F2 gene.

See Glycoprotein IIb/IIIa and Thrombin

Thromboxane A2

Thromboxane A2 (TXA2) is a type of thromboxane that is produced by activated platelets during hemostasis and has prothrombotic properties: it stimulates activation of new platelets as well as increases platelet aggregation.

See Glycoprotein IIb/IIIa and Thromboxane A2

Tirofiban

Tirofiban, sold under the brand name Aggrastat, is an antiplatelet medication.

See Glycoprotein IIb/IIIa and Tirofiban

Von Willebrand factor

Von Willebrand factor (VWF) is a blood glycoprotein that promotes hemostasis, specifically, platelet adhesion.

See Glycoprotein IIb/IIIa and Von Willebrand factor

References

[1] https://en.wikipedia.org/wiki/Glycoprotein_IIb/IIIa

Also known as GP IIb/IIIa, GPIIb/IIIa, IIb-IIIa, Integrin αIIbβ3, Platelet glycoprotein gpiib-iiia complex.

Unionpedia is a concept map or semantic network organized like an encyclopedia – dictionary. It gives a brief definition of each concept and its relationships.

This is a giant online mental map that serves as a basis for concept diagrams. It's free to use and each article or document can be downloaded. It's a tool, resource or reference for study, research, education, learning or teaching, that can be used by teachers, educators, pupils or students; for the academic world: for school, primary, secondary, high school, middle, technical degree, college, university, undergraduate, master's or doctoral degrees; for papers, reports, projects, ideas, documentation, surveys, summaries, or thesis. Here is the definition, explanation, description, or the meaning of each significant on which you need information, and a list of their associated concepts as a glossary. Available in English, Spanish, Portuguese, Japanese, Chinese, French, German, Italian, Polish, Dutch, Russian, Arabic, Hindi, Swedish, Ukrainian, Hungarian, Catalan, Czech, Hebrew, Danish, Finnish, Indonesian, Norwegian, Romanian, Turkish, Vietnamese, Korean, Thai, Greek, Bulgarian, Croatian, Slovak, Lithuanian, Filipino, Latvian, Estonian and Slovenian. More languages soon.

The information is based on Wikipedia articles and other Wikimedia projects, and it's available under the Creative Commons Attribution-ShareAlike License.

Unionpedia is not endorsed by or affiliated with the Wikimedia Foundation.

Google Play, Android and the Google Play logo are trademarks of Google Inc.

Languages