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36 relations: Antibody, Beta sheet, CCR5, CD4, Cell membrane, Conformational change, DC-SIGN, Electrostatics, Endoplasmic reticulum, Entry inhibitor, Env (gene), Fostemsavir, Furin, Gene, Glycoprotein, Gp41, Heparan sulfate, HIV vaccine, Hydrogen bond, Lloyd Mayer, Maraviroc, Molecular mass, National Institutes of Health, Protease, Protein dimer, Receptor (biochemistry), Red Queen hypothesis, Science, Structure and genome of HIV, Subtypes of HIV, T cell, T helper cell, Transmembrane protein, Unified atomic mass unit, Van der Waals force, Viral envelope.
Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.
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Beta sheet
The β-sheet (also β-pleated sheet) is a common motif of regular secondary structure in proteins.
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CCR5
C-C chemokine receptor type 5, also known as CCR5 or CD195, is a protein on the surface of white blood cells that is involved in the immune system as it acts as a receptor for chemokines.
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CD4
In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells.
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Cell membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).
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Conformational change
In biochemistry, a conformational change is a change in the shape of a macromolecule, often induced by environmental factors.
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DC-SIGN
DC-SIGN (Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin) also known as CD209 ('''C'''luster of '''D'''ifferentiation 209) is a protein which in humans is encoded by the CD209 gene.
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Electrostatics
Electrostatics is a branch of physics that studies electric charges at rest.
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Endoplasmic reticulum
The endoplasmic reticulum (ER) is a type of organelle found in eukaryotic cells that forms an interconnected network of flattened, membrane-enclosed sacs or tube-like structures known as cisternae.
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Entry inhibitor
Entry inhibitors, also known as fusion inhibitors, are a class of antiretroviral drugs, used in combination therapy for the treatment of HIV infection.
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Env (gene)
Env is a viral gene that encodes the protein forming the viral envelope.
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Fostemsavir
Fostemsavir (BMS-663068) is an experimental HIV entry inhibitor and a prodrug of temsavir (BMS-626529).
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Furin
Furin is a protein that in humans is encoded by the FURIN gene.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Glycoprotein
Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to amino acid side-chains.
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Gp41
Gp41 also known as glycoprotein 41 is a subunit of the envelope protein complex of retroviruses, including human immunodeficiency virus (HIV).
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Heparan sulfate
Heparan sulfate (HS) is a linear polysaccharide found in all animal tissues.
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HIV vaccine
An HIV vaccine is a vaccine which would either protect individuals who do not have HIV from contracting that virus, or otherwise may have a therapeutic effect for persons who have or later contract HIV/AIDS.
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Hydrogen bond
A hydrogen bond is a partially electrostatic attraction between a hydrogen (H) which is bound to a more electronegative atom such as nitrogen (N), oxygen (O), or fluorine (F), and another adjacent atom bearing a lone pair of electrons.
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Lloyd Mayer
Lloyd Mayer (June 21, 1952 – September 5, 2013) was an American gastroenterologist and immunologist.
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Maraviroc
Maraviroc (INN, brand-named Selzentry, or Celsentri outside the U.S.) is an antiretroviral drug in the CCR5 receptor antagonist class used in the treatment of HIV infection.
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Molecular mass
Relative Molecular mass or molecular weight is the mass of a molecule.
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National Institutes of Health
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.
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Protease
A protease (also called a peptidase or proteinase) is an enzyme that performs proteolysis: protein catabolism by hydrolysis of peptide bonds.
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Protein dimer
In biochemistry, a protein dimer is a macromolecular complex formed by two protein monomers, or single proteins, which are usually non-covalently bound.
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Receptor (biochemistry)
In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.
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Red Queen hypothesis
The Red Queen hypothesis, also referred to as Red Queen's, Red Queen's race or the Red Queen effect, is an evolutionary hypothesis which proposes that organisms must constantly adapt, evolve, and proliferate not merely to gain reproductive advantage, but also simply to survive while pitted against ever-evolving opposing organisms in an ever-changing environment.
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Science
R. P. Feynman, The Feynman Lectures on Physics, Vol.1, Chaps.1,2,&3.
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Structure and genome of HIV
The genome and proteins of HIV (human immunodeficiency virus) have been the subject of extensive research since the discovery of the virus in 1983.
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Subtypes of HIV
One of the obstacles to treatment of the human immunodeficiency virus is its high genetic variability.
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T cell
A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.
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T helper cell
The T helper cells (Th cells) are a type of T cell that play an important role in the immune system, particularly in the adaptive immune system.
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Transmembrane protein
A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the biological membrane to which it is permanently attached.
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Unified atomic mass unit
The unified atomic mass unit or dalton (symbol: u, or Da) is a standard unit of mass that quantifies mass on an atomic or molecular scale (atomic mass).
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Van der Waals force
In molecular physics, the van der Waals forces, named after Dutch scientist Johannes Diderik van der Waals, are distance-dependent interactions between atoms or molecules.
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Viral envelope
Some viruses (e.g. HIV and many animal viruses) have viral envelopes covering their protective protein capsids.
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Redirects here:
GP-120, GP120, Gp-120, Gp120, Hiv envelope protein gp120.
References
[1] https://en.wikipedia.org/wiki/Envelope_glycoprotein_GP120
