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Henderson–Hasselbalch equation

Index Henderson–Hasselbalch equation

In chemistry, the Henderson–Hasselbalch equation describes the derivation of pH as a measure of acidity (using, the negative log of the acid dissociation constant) in biological and chemical systems. [1]

40 relations: Acid, Acid dissociation constant, Acid strength, Acid–base homeostasis, Acid–base reaction, Acidosis, Alkalosis, American Journal of Physiology, Base (chemistry), Bicarbonate, Bicarbonate buffer system, Blood, Blood gas tension, Brønsted–Lowry acid–base theory, Buffer solution, Carbon dioxide, Carbonic acid, Chemical equilibrium, Chemistry, Cologarithm, Conjugate acid, Dissociation (chemistry), Henry's law, Ion, Isoelectric point, Journal of Chemical Education, Karl Albert Hasselbalch, Lawrence Joseph Henderson, Litre, Logarithm, Metabolic acidosis, Molar concentration, Mole (unit), Partial pressure, PH, Solubility, The Chemical Educator, The FEBS Journal, Titration, Torr.

Acid

An acid is a molecule or ion capable of donating a hydron (proton or hydrogen ion H+), or, alternatively, capable of forming a covalent bond with an electron pair (a Lewis acid).

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Acid dissociation constant

An acid dissociation constant, Ka, (also known as acidity constant, or acid-ionization constant) is a quantitative measure of the strength of an acid in solution.

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Acid strength

The strength of an acid refers to its ability or tendency to lose a proton (H+).

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Acid–base homeostasis

Acid–base homeostasis is the homeostatic regulation of the pH of the body's extracellular fluid (ECF).

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Acid–base reaction

An acid–base reaction is a chemical reaction that occurs between an acid and a base, which can be used to determine pH.

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Acidosis

Acidosis is a process causing increased acidity in the blood and other body tissues (i.e., an increased hydrogen ion concentration).

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Alkalosis

Alkalosis is the result of a process reducing hydrogen ion concentration of arterial blood plasma (alkalemia).

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American Journal of Physiology

The American Journal of Physiology is a peer-reviewed scientific journal on physiology published by the American Physiological Society.

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Base (chemistry)

In chemistry, bases are substances that, in aqueous solution, release hydroxide (OH−) ions, are slippery to the touch, can taste bitter if an alkali, change the color of indicators (e.g., turn red litmus paper blue), react with acids to form salts, promote certain chemical reactions (base catalysis), accept protons from any proton donor, and/or contain completely or partially displaceable OH− ions.

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Bicarbonate

In inorganic chemistry, bicarbonate (IUPAC-recommended nomenclature: hydrogencarbonate) is an intermediate form in the deprotonation of carbonic acid.

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Bicarbonate buffer system

The bicarbonate buffer system is an acid-base homeostatic mechanism involving the balance of carbonic acid (H2CO3), bicarbonate ion (HCO), and carbon dioxide (CO2) in order to maintain pH in the blood and duodenum, among other tissues, to support proper metabolic function.

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Blood

Blood is a body fluid in humans and other animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells.

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Blood gas tension

Blood gas tension refers to the partial pressure of gases in blood.

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Brønsted–Lowry acid–base theory

The Brønsted–Lowry theory is an acid–base reaction theory which was proposed independently by Johannes Nicolaus Brønsted and Thomas Martin Lowry in 1923.

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Buffer solution

A buffer solution (more precisely, pH buffer or hydrogen ion buffer) is an aqueous solution consisting of a mixture of a weak acid and its conjugate base, or vice versa.

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Carbon dioxide

Carbon dioxide (chemical formula) is a colorless gas with a density about 60% higher than that of dry air.

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Carbonic acid

Carbonic acid is a chemical compound with the chemical formula H2CO3 (equivalently OC(OH)2).

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Chemical equilibrium

In a chemical reaction, chemical equilibrium is the state in which both reactants and products are present in concentrations which have no further tendency to change with time, so that there is no observable change in the properties of the system.

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Chemistry

Chemistry is the scientific discipline involved with compounds composed of atoms, i.e. elements, and molecules, i.e. combinations of atoms: their composition, structure, properties, behavior and the changes they undergo during a reaction with other compounds.

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Cologarithm

In mathematics, the base-b cologarithm, sometimes shortened to colog, of a number is the base-b logarithm of the reciprocal of the number.

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Conjugate acid

A conjugate acid, within the Brønsted–Lowry acid–base theory, is a species formed by the reception of a proton (H+) by a base—in other words, it is a base with a hydrogen ion added to it.

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Dissociation (chemistry)

Dissociation in chemistry and biochemistry is a general process in which molecules (or ionic compounds such as salts, or complexes) separate or split into smaller particles such as atoms, ions or radicals, usually in a reversible manner.

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Henry's law

In chemistry, Henry's law is a gas law that states that the amount of dissolved gas is proportional to its partial pressure in the gas phase.

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Ion

An ion is an atom or molecule that has a non-zero net electrical charge (its total number of electrons is not equal to its total number of protons).

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Isoelectric point

The isoelectric point (pI, pH(I), IEP), is the pH at which a particular molecule carries no net electrical charge or is electrically neutral in the statistical mean.

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Journal of Chemical Education

The Journal of Chemical Education is a monthly peer-reviewed academic journal available in both print and electronic versions.

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Karl Albert Hasselbalch

Karl Albert Hasselbalch (1 November 1874 in Aastrup, Denmark – 19 September 1962) was a physician and chemist.

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Lawrence Joseph Henderson

Lawrence Joseph Henderson (June 3, 1878, Lynn, Massachusetts – February 10, 1942, Cambridge, Massachusetts) was a physiologist, chemist, biologist, philosopher, and sociologist.

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Litre

The litre (SI spelling) or liter (American spelling) (symbols L or l, sometimes abbreviated ltr) is an SI accepted metric system unit of volume equal to 1 cubic decimetre (dm3), 1,000 cubic centimetres (cm3) or 1/1,000 cubic metre. A cubic decimetre (or litre) occupies a volume of 10 cm×10 cm×10 cm (see figure) and is thus equal to one-thousandth of a cubic metre. The original French metric system used the litre as a base unit. The word litre is derived from an older French unit, the litron, whose name came from Greek — where it was a unit of weight, not volume — via Latin, and which equalled approximately 0.831 litres. The litre was also used in several subsequent versions of the metric system and is accepted for use with the SI,, p. 124. ("Days" and "hours" are examples of other non-SI units that SI accepts.) although not an SI unit — the SI unit of volume is the cubic metre (m3). The spelling used by the International Bureau of Weights and Measures is "litre", a spelling which is shared by almost all English-speaking countries. The spelling "liter" is predominantly used in American English. One litre of liquid water has a mass of almost exactly one kilogram, because the kilogram was originally defined in 1795 as the mass of one cubic decimetre of water at the temperature of melting ice. Subsequent redefinitions of the metre and kilogram mean that this relationship is no longer exact.

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Logarithm

In mathematics, the logarithm is the inverse function to exponentiation.

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Metabolic acidosis

Metabolic acidosis is a condition that occurs when the body produces excessive quantities of acid or when the kidneys are not removing enough acid from the body.

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Molar concentration

Molar concentration (also called molarity, amount concentration or substance concentration) is a measure of the concentration of a chemical species, in particular of a solute in a solution, in terms of amount of substance per unit volume of solution.

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Mole (unit)

The mole, symbol mol, is the SI unit of amount of substance.

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Partial pressure

In a mixture of gases, each gas has a partial pressure which is the hypothetical pressure of that gas if it alone occupied the entire volume of the original mixture at the same temperature.

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PH

In chemistry, pH is a logarithmic scale used to specify the acidity or basicity of an aqueous solution.

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Solubility

Solubility is the property of a solid, liquid or gaseous chemical substance called solute to dissolve in a solid, liquid or gaseous solvent.

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The Chemical Educator

The Chemical Educator is a peer-reviewed journal in chemical education.

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The FEBS Journal

The FEBS Journal is a biweekly peer-reviewed scientific journal published by John Wiley & Sons on behalf of the Federation of European Biochemical Societies.

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Titration

Titration, also known as titrimetry, is a common laboratory method of quantitative chemical analysis that is used to determine the concentration of an identified analyte.

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Torr

The torr (symbol: Torr) is a unit of pressure based on an absolute scale, now defined as exactly of a standard atmosphere (101.325 kPa).

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References

[1] https://en.wikipedia.org/wiki/Henderson–Hasselbalch_equation

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