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30 relations: Ataxia telangiectasia and Rad3 related, ATM serine/threonine kinase, BARD1, Bloom syndrome protein, BRCA1, CBX1, CHD4, Chromatin, Chromatin remodeling, DNA, DNA-PKcs, Eukaryote, Gene, Heterochromatin protein 1, Histone, Histone H2A, Histone H3, Histone methylation, Ionizing radiation, MDC1, Mi-2/NuRD complex, MRE11A, MRN complex, Nibrin, Protein complex, Protein–protein interaction, Rad50, RAD51, RNF8, TP53BP1.
Ataxia telangiectasia and Rad3 related
Serine/threonine-protein kinase ATR also known as ataxia telangiectasia and Rad3-related protein (ATR) or FRAP-related protein 1 (FRP1) is an enzyme that, in humans, is encoded by the ATR gene.
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ATM serine/threonine kinase
ATM serine/threonine kinase, symbol ATM, is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks.
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BARD1
BRCA1-associated RING domain protein 1 is a protein that in humans is encoded by the BARD1 gene.
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Bloom syndrome protein
Bloom syndrome protein is a protein that in humans is encoded by the BLM gene and is not expressed in Bloom syndrome.
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BRCA1
BRCA1 and BRCA1 are a human gene and its protein product, respectively.
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CBX1
Chromobox protein homolog 1 is a protein that in humans is encoded by the CBX1 gene.
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CHD4
Chromodomain-helicase-DNA-binding protein 4 is an enzyme that in humans is encoded by the CHD4 gene.
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Chromatin
Chromatin is a complex of macromolecules found in cells, consisting of DNA, protein, and RNA.
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Chromatin remodeling
Chromatin remodeling is the dynamic modification of chromatin architecture to allow access of condensed genomic DNA to the regulatory transcription machinery proteins, and thereby control gene expression.
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DNA
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
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DNA-PKcs
DNA-dependent protein kinase, catalytic subunit, also known as DNA-PKcs, is an enzyme that in humans is encoded by the gene designated as PRKDC or XRCC7.
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Eukaryote
Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Heterochromatin protein 1
The family of heterochromatin protein 1 (HP1) ("Chromobox Homolog", CBX) consists of highly conserved proteins, which have important functions in the cell nucleus.
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Histone
In biology, histones are highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units called nucleosomes.
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Histone H2A
Histone H2A is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells.
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Histone H3
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells.
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Histone methylation
Histone methylation is a process by which methyl groups are transferred to amino acids of histone proteins that make up nucleosomes, which the DNA double helix wraps around to form chromosomes.
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Ionizing radiation
Ionizing radiation (ionising radiation) is radiation that carries enough energy to liberate electrons from atoms or molecules, thereby ionizing them.
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MDC1
Mediator of DNA damage checkpoint protein 1 is a 2080 amino acid long protein that in humans is encoded by the MDC1 gene located on the short arm (p) of chromosome 6.
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Mi-2/NuRD complex
In the field of molecular biology, the Mi-2/NuRD (Nucleosome Remodeling Deacetylase) complex, is a group of associated proteins with both ATP-dependent chromatin remodeling and histone deacetylase activities.
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MRE11A
Double-strand break repair protein MRE11A is a protein that in humans is encoded by the MRE11A gene.
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MRN complex
The MRN complex (MRX complex in yeast) is a protein complex consisting of Mre11, Rad50 and Nbs1 (also known as Nibrin in humans and as Xrs2 in yeast).
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Nibrin
Nibrin, also known as NBN or NBS1, is a protein which in humans is encoded by the NBN gene.
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Protein complex
A protein complex or multiprotein complex is a group of two or more associated polypeptide chains.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Rad50
DNA repair protein RAD50, also known as RAD50, is a protein that in humans is encoded by the RAD50 gene.
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RAD51
RAD51 is a eukaryotic gene.
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RNF8
E3 ubiquitin-protein ligase RNF8 is an enzyme that in humans is encoded by the RNF8 gene.
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TP53BP1
Tumor suppressor p53-binding protein 1 also known as p53-binding protein 1 or 53BP1 is a protein that in humans is encoded by the TP53BP1 gene.
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Redirects here:
H2A.X, H2AFX (gene), H2AX, H2a.x, H2ax.
References
[1] https://en.wikipedia.org/wiki/H2AFX
