12 relations: Alternative splicing, Beta-2 microglobulin, Chromosome 6, Gene, Hepcidin, HFE hereditary haemochromatosis, MHC class I, Protein, Protein–protein interaction, Transferrin, Transferrin receptor, Transferrin receptor 1.
Alternative splicing
Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.
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Beta-2 microglobulin
β2 microglobulin also known as B2M is a component of MHC class I molecules, MHC class I molecules have α1, α2, and α3 proteins which are present on all nucleated cells (excludes red blood cells).
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Chromosome 6
Chromosome 6 is one of the 23 pairs of chromosomes in humans.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Hepcidin
Hepcidin is a protein that in humans is encoded by the HAMP gene.
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HFE hereditary haemochromatosis
Haemochromatosis (or hemochromatosis) type 1 autosomal recessive is a hereditary disease characterized by excessive intestinal absorption of dietary iron resulting in a pathological increase in total body iron stores.
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MHC class I
MHC class I molecules are one of two primary classes of major histocompatibility complex (MHC) molecules (the other being MHC class II) and are found on the cell surface of all nucleated cells in the bodies of jawed vertebrates.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Transferrin
Transferrins are iron-binding blood plasma glycoproteins that control the level of free iron (Fe) in biological fluids.
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Transferrin receptor
Transferrin receptor (TfR) is a carrier protein for transferrin.
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Transferrin receptor 1
Transferrin receptor protein 1 (TfR1), also known as Cluster of Differentiation 71 (CD71), is a protein that in humans is encoded by the TFRC gene.
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C282Y, HFE gene, HFE protein, HFE1.