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79 relations: Active site, Acute myeloid leukemia, Adenine, Alternative splicing, Alzheimer's disease, Amino acid, Antioxidant, Apoptosis, Arginine, Asparagine, Aspartic acid, ATM serine/threonine kinase, Base pair, C-terminus, Caenorhabditis elegans, Cardiovascular disease, Caspase 6, Cat, CDNA library, Cell cycle checkpoint, Cell nucleus, Chromosome 7, Cloning, CREB-binding protein, CTBP1, Cytoplasm, Cytosine, Dictyostelium, DNA, Dog, Drosophila, Enzyme, EP300, Exon, Fibrosis, Gene, HIPK1, HIPK3, HMGA1, Homeobox, Human embryogenesis, Intron, Isoleucine, Lysine, Mdm2, Messenger RNA, Missense mutation, Mutation, Myelodysplastic syndrome, N-terminus, ..., Oxidative stress, Oxidizing agent, P53, PEST sequence, Phosphorylation, PIN1, Point mutation, Proteasome, Protein isoform, Protein kinase, Reactive oxygen species, Serine, Sheep, SIAH1, Signal transduction, SKI protein, SUMO protein, Tachykinin receptor 3, Threonine, Thymine, TP53INP1, Transcription factor, Tryptophan, Two-hybrid screening, Unified atomic mass unit, Wild type, WSB1, Zebrafish, Zinc. Expand index (29 more) »
Active site
In biology, the active site is the region of an enzyme where substrate molecules bind and undergo a chemical reaction.
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Acute myeloid leukemia
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cells.
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Adenine
Adenine (A, Ade) is a nucleobase (a purine derivative).
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Alternative splicing
Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.
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Alzheimer's disease
Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time.
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Amino acid
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
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Antioxidant
Antioxidants are molecules that inhibit the oxidation of other molecules.
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Apoptosis
Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.
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Arginine
Arginine (symbol Arg or R) is an α-amino acid that is used in the biosynthesis of proteins.
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Asparagine
Asparagine (symbol Asn or N), is an α-amino acid that is used in the biosynthesis of proteins.
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Aspartic acid
Aspartic acid (symbol Asp or D; salts known as aspartates), is an α-amino acid that is used in the biosynthesis of proteins.
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ATM serine/threonine kinase
ATM serine/threonine kinase, symbol ATM, is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks.
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Base pair
A base pair (bp) is a unit consisting of two nucleobases bound to each other by hydrogen bonds.
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C-terminus
The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).
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Caenorhabditis elegans
Caenorhabditis elegans is a free-living (not parasitic), transparent nematode (roundworm), about 1 mm in length, that lives in temperate soil environments.
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Cardiovascular disease
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels.
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Caspase 6
Caspase-6 is an enzyme that in humans is encoded by the CASP6 gene.
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Cat
The domestic cat (Felis silvestris catus or Felis catus) is a small, typically furry, carnivorous mammal.
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CDNA library
A cDNA library is a combination of cloned cDNA (complementary DNA) fragments inserted into a collection of host cells, which together constitute some portion of the transcriptome of the organism and are stored as a "library".
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Cell cycle checkpoint
Cell cycle checkpoints are control mechanisms in eukaryotic cells which ensure proper division of the cell.
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Cell nucleus
In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.
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Chromosome 7
Chromosome 7 is one of the 23 pairs of chromosomes in humans.
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Cloning
Cloning is the process of producing genetically identical individuals of an organism either naturally or artificially.
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CREB-binding protein
CREB-binding protein, also known as CREBBP or CBP, is a protein that in humans is encoded by the CREBBP gene.
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CTBP1
C-terminal-binding protein 1 also known as CtBP1 is a protein that in humans is encoded by the CTBP1 gene.
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Cytoplasm
In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.
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Cytosine
Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).
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Dictyostelium
Dictyostelium is a genus of single- and multi-celled eukaryotic, phagotrophic bacterivores.
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DNA
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
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Dog
The domestic dog (Canis lupus familiaris when considered a subspecies of the gray wolf or Canis familiaris when considered a distinct species) is a member of the genus Canis (canines), which forms part of the wolf-like canids, and is the most widely abundant terrestrial carnivore.
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Drosophila
Drosophila is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit.
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Enzyme
Enzymes are macromolecular biological catalysts.
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EP300
Histone acetyltransferase p300 also known as p300 HAT or E1A-associated protein p300 (where E1A.
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Exon
An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.
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Fibrosis
Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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HIPK1
Homeodomain-interacting protein kinase 1 is an enzyme that in humans is encoded by the HIPK1 gene.
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HIPK3
Homeodomain-interacting protein kinase 3 is an enzyme that in humans is encoded by the HIPK3 gene.
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HMGA1
High-mobility group protein HMG-I/HMG-Y is a protein that in humans is encoded by the HMGA1 gene.
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Homeobox
A homeobox is a DNA sequence, around 180 base pairs long, found within genes that are involved in the regulation of patterns of anatomical development (morphogenesis) in animals, fungi and plants.
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Human embryogenesis
Human embryogenesis is the process of cell division and cellular differentiation of the embryo that occurs during the early stages of development.
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Intron
An intron is any nucleotide sequence within a gene that is removed by RNA splicing during maturation of the final RNA product.
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Isoleucine
Isoleucine (symbol Ile or I) is an α-amino acid that is used in the biosynthesis of proteins.
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Lysine
Lysine (symbol Lys or K) is an α-amino acid that is used in the biosynthesis of proteins.
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Mdm2
Mouse double minute 2 homolog (MDM2) also known as E3 ubiquitin-protein ligase Mdm2 is a protein that in humans is encoded by the MDM2 gene.
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Messenger RNA
Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
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Missense mutation
In genetics, a missense mutation is a point mutation in which a single nucleotide change results in a codon that codes for a different amino acid.
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Mutation
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.
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Myelodysplastic syndrome
Myelodysplastic syndromes (MDS) are a group of cancers in which immature blood cells in the bone marrow do not mature and therefore do not become healthy blood cells.
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N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
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Oxidative stress
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage.
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Oxidizing agent
In chemistry, an oxidizing agent (oxidant, oxidizer) is a substance that has the ability to oxidize other substances — in other words to cause them to lose electrons.
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P53
Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice).
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PEST sequence
A PEST sequence is a peptide sequence that is rich in proline (P), glutamic acid (E), serine (S), and threonine (T).
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Phosphorylation
In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.
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PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 is an enzyme that in humans is encoded by the PIN1 gene.
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Point mutation
A point mutation is a genetic mutation where a single nucleotide base is changed, inserted or deleted from a sequence of DNA or RNA.
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Proteasome
Proteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds.
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Protein isoform
A protein isoform, or "protein variant" is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.
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Protein kinase
A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation).
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Reactive oxygen species
Reactive oxygen species (ROS) are chemically reactive chemical species containing oxygen.
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Serine
Serine (symbol Ser or S) is an ɑ-amino acid that is used in the biosynthesis of proteins.
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Sheep
Domestic sheep (Ovis aries) are quadrupedal, ruminant mammal typically kept as livestock.
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SIAH1
E3 ubiquitin-protein ligase SIAH1 is an enzyme that in humans is encoded by the SIAH1 gene.
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Signal transduction
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.
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SKI protein
The SKI protein is a nuclear proto-oncogene that is associated with tumors at high cellular concentrations.
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SUMO protein
Small Ubiquitin-like Modifier (or SUMO) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function.
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Tachykinin receptor 3
Tachykinin receptor 3, also known as TACR3, is a protein which in humans is encoded by the TACR3 gene.
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Threonine
Threonine (symbol Thr or T) is an amino acid that is used in the biosynthesis of proteins.
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Thymine
---> Thymine (T, Thy) is one of the four nucleobases in the nucleic acid of DNA that are represented by the letters G–C–A–T.
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TP53INP1
Tumor protein p53-inducible nuclear protein 1 is a protein that in humans is encoded by the TP53INP1 gene.
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Transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.
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Tryptophan
Tryptophan (symbol Trp or W) is an α-amino acid that is used in the biosynthesis of proteins.
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Two-hybrid screening
Two-hybrid screening (originally known as yeast two-hybrid system or Y2H) is a molecular biology technique used to discover protein–protein interactions (PPIs) and protein–DNA interactions by testing for physical interactions (such as binding) between two proteins or a single protein and a DNA molecule, respectively.
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Unified atomic mass unit
The unified atomic mass unit or dalton (symbol: u, or Da) is a standard unit of mass that quantifies mass on an atomic or molecular scale (atomic mass).
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Wild type
Wild type (WT) refers to the phenotype of the typical form of a species as it occurs in nature.
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WSB1
WD repeat and SOCS box-containing protein 1 is a protein that in humans is encoded by the WSB1 gene.
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Zebrafish
The zebrafish (Danio rerio) is a freshwater fish belonging to the minnow family (Cyprinidae) of the order Cypriniformes.
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Zinc
Zinc is a chemical element with symbol Zn and atomic number 30.
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References
[1] https://en.wikipedia.org/wiki/HIPK2
