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HIV tropism

Index HIV tropism

HIV tropism refers to the cell type that the human immunodeficiency virus (HIV) infects and replicates in. [1]

17 relations: CCL5, CCR5, CD4, Cell (biology), Cell type, Chemokine, CXCR4, Envelope glycoprotein GP120, HIV, Ligand, Macrophage, Macrophage inflammatory protein, Stromal cell-derived factor 1, Syncytium, T helper cell, Tissue tropism, Trofile assay.


Chemokine (C-C motif) ligand 5 (also CCL5) is a protein which in humans is encoded by the CCL5 gene.

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C-C chemokine receptor type 5, also known as CCR5 or CD195, is a protein on the surface of white blood cells that is involved in the immune system as it acts as a receptor for chemokines.

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In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells.

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Cell (biology)

The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.

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Cell type

A cell type is a classification used to distinguish between morphologically or phenotypically distinct cell forms within a species.

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Chemokines (Greek -kinos, movement) are a family of small cytokines, or signaling proteins secreted by cells.

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C-X-C chemokine receptor type 4 (CXCR-4) also known as fusin or CD184 (cluster of differentiation 184) is a protein that in humans is encoded by the CXCR4 gene.

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Envelope glycoprotein GP120

Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope.

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The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS).

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In coordination chemistry, a ligand is an ion or molecule (functional group) that binds to a central metal atom to form a coordination complex.

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Macrophages (big eaters, from Greek μακρός (makrós).

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Macrophage inflammatory protein

Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines.

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Stromal cell-derived factor 1

The stromal cell-derived factor 1 (SDF1), also known as C-X-C motif chemokine 12 (CXCL12), is a chemokine protein that in humans is encoded by the CXCL12 gene on chromosome 10.

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A syncytium or symplasm (plural syncytia; from Greek: σύν (syn).

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T helper cell

The T helper cells (Th cells) are a type of T cell that play an important role in the immune system, particularly in the adaptive immune system.

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Tissue tropism

Tissue tropism is the cells and tissues of a host that support growth of a particular virus or bacterium.

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Trofile assay

The Trofile assay is a blood test that identifies the tropism of a patient's HIV.

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Redirects here:

Macrophage-tropic virus, R5 virus, R5X4, X4 virus.


[1] https://en.wikipedia.org/wiki/HIV_tropism

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