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HSD17B3

Index HSD17B3

17β-Hydroxysteroid dehydrogenase 3 (17β-HSD3) is an enzyme that in humans is encoded by the HSD17B3 gene and is involved in androgen steroidogenesis. [1]

10 relations: Androgen, Androstenedione, Enzyme, Gene, Nicotinamide adenine dinucleotide phosphate, Pseudohermaphroditism, Steroid, Testicle, Testosterone, 17β-Hydroxysteroid dehydrogenase.

Androgen

An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.

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Androstenedione

Androstenedione, or 4-androstenedione (abbreviated as A4 or Δ4-dione), also known as androst-4-ene-3,17-dione, is an endogenous weak androgen steroid hormone and intermediate in the biosynthesis of estrone and of testosterone from dehydroepiandrosterone (DHEA).

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Enzyme

Enzymes are macromolecular biological catalysts.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Nicotinamide adenine dinucleotide phosphate

Nicotinamide adenine dinucleotide phosphate, abbreviated NADP or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent.

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Pseudohermaphroditism

Pseudohermaphroditism, or pseudo-hermaphroditism, is an old clinical term for an organism that is born with primary sex characteristics of one sex but develops the secondary sex characteristics that are different from what would be expected on the basis of the gonadal tissue (ovary or testis).

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Steroid

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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Testicle

The testicle or testis is the male reproductive gland in all animals, including humans.

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Testosterone

Testosterone is the primary male sex hormone and an anabolic steroid.

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17β-Hydroxysteroid dehydrogenase

17β-Hydroxysteroid dehydrogenases (17β-HSD, HSD17B), also 17-ketosteroid reductases (17-KSR), are a group of alcohol oxidoreductases which catalyze the reduction of 17-ketosteroids and the dehydrogenation of 17β-hydroxysteroids in steroidogenesis and steroid metabolism.

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Redirects here:

17 beta hydroxysteroid dehydrogenase 3, 17 beta hydroxysteroid dehydrogenase type 3, 17β-HSD 3, 17β-HSD III, 17β-HSD type 3, 17β-HSD type III, 17β-HSD3, 17β-HSDIII, 17β-Hydroxysteroid dehydrogenase 3, 17β-Hydroxysteroid dehydrogenase III, 17β-Hydroxysteroid dehydrogenase type 3, 17β-Hydroxysteroid dehydrogenase type III, 17β-hydroxysteroid dehydrogenase 3, 17β-hydroxysteroid dehydrogenase III, 17β-hydroxysteroid dehydrogenase type 3, 17β-hydroxysteroid dehydrogenase type III, HSD17B3 (gene).

References

[1] https://en.wikipedia.org/wiki/HSD17B3

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