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108 relations: Aorta-gonad-mesonephros, Assay, Ataxin 1, B cell, Band cell, Basophil, Blood cell, Bone marrow, CD117, CD133, CD135, CD244, CD34, CD38, CD4, CD48, CD59, CD90, Cell counting, Cell potency, CFU-E, CFU-Eos, CFU-GEMM, CFU-GM, CFU-Meg, Cluster of differentiation, Cobblestone, Colony-forming unit, CXCR4, DNA polymerase mu, Emperipolesis, Endoglin, Eosinophil, Erythropoiesis, Extramedullary hematopoiesis, Fc receptor, Femur, Flow cytometry, Granulocyte, Granulopoiesis, Haematopoiesis, Hamming distance, Hematopoietic stem cell, Hematopoietic stem cell niche, Hematopoietic stem cell transplantation, Integrin, Integrin alpha M, Interleukin 7, Irving Weissman, LIG4, ..., Lineage markers, List of human cell types derived from the germ layers, Liver, Lymphatic system, Lymphoblast, Lymphocyte, Lymphopoiesis, Macrophage, Megakaryoblast, Megakaryocyte, Megakaryocyte–erythroid progenitor cell, Mesoderm, Metamyelocyte, Monoblast, Monocyte, Monocytopoiesis, Multipotentiality, Myeloblast, Myelocyte, Myeloid tissue, Myelopoiesis, Natural killer cell, Neutrophil, Non-homologous end joining, Non-homologous end-joining factor 1, Nucleated red blood cell, Osteoclast, Pelvis, Platelet, Proerythroblast, Prolymphocyte, Promegakaryocyte, Promonocyte, Promyelocyte, PTPRC, Red blood cell, Reticulocyte, Severe combined immunodeficiency, Side population, Signaling lymphocytic activation molecule, SLAMF1, Spleen, Stanford University, Stem cell, Stem cell factor, Stem-cell niche, Sternum, Stromal cell-derived factor 1, Symbolic dynamics, T cell, Thrombopoiesis, Thymic nurse cell, Thymocyte, Thymus, Transforming growth factor, Umbilical cord, Venous blood, Word sense. Expand index (58 more) »
Aorta-gonad-mesonephros
The aorta-gonad-mesonephros (AGM) is a region of embryonic mesoderm that develops during embryonic development from the para-aortic splanchnopleura in chick, mouse and human embryos.
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Assay
An assay is an investigative (analytic) procedure in laboratory medicine, pharmacology, environmental biology and molecular biology for qualitatively assessing or quantitatively measuring the presence, amount, or functional activity of a target entity (the analyte).
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Ataxin 1
Ataxin-1 is a DNA-binding protein which in humans is encoded by the ATXN1 gene.
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B cell
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.
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Band cell
A band cell (also called band neutrophil, band form or stab cell) is a cell undergoing granulopoiesis, derived from a metamyelocyte, and leading to a mature granulocyte.
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Basophil
Basophils are a type of white blood cells.
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Blood cell
A blood cell, also called a haematopoietic cell, hemocyte, or hematocyte, is a cell produced through hematopoiesis and found mainly in the blood.
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Bone marrow
Bone marrow is a semi-solid tissue which may be found within the spongy or cancellous portions of bones.
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CD117
Mast/stem cell growth factor receptor (SCFR), also known as proto-oncogene c-Kit or tyrosine-protein kinase Kit or CD117, is a receptor tyrosine kinase protein that in humans is encoded by the KIT gene.
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CD133
CD133 antigen, also known as prominin-1, is a glycoprotein that in humans is encoded by the PROM1 gene.
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CD135
Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3), receptor-type tyrosine-protein kinase FLT3, or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene.
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CD244
CD244 (Cluster of Differentiation 244) is a human protein encoded by the gene.
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CD34
CD34 is a transmembrane phosphoglycoprotein protein encoded by the CD34 gene in humans, mice, rats and other species.
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CD38
CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells.
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CD4
In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells.
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CD48
CD48 antigen (Cluster of Differentiation 48) also known as B-lymphocyte activation marker (BLAST-1) or signaling lymphocytic activation molecule 2 (SLAMF2) is a protein that in humans is encoded by the CD48 gene.
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CD59
CD59 glycoprotein, also known as MAC-inhibitory protein (MAC-IP), membrane inhibitor of reactive lysis (MIRL), or protectin, is a protein that in humans is encoded by the CD59 gene.
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CD90
Thy-1 or CD90 (Cluster of Differentiation 90) is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a thymocyte antigen.
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Cell counting
Cell counting is any of various methods for the counting or similar quantification of cells in the life sciences, including medical diagnosis and treatment.
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Cell potency
Cell potency is a cell's ability to differentiate into other cell types The more cell types a cell can differentiate into, the greater its potency.
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CFU-E
CFU-E stands for '''Colony Forming Unit-Hematopoietic'''.
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CFU-Eos
CFU-Eo is a colony forming unit that gives rise to eosinophils.
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CFU-GEMM
CFU-GEMM is a colony forming unit that generates myeloid cells.
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CFU-GM
CFU-GM (or "GMP", for "granulocyte-macrophage progenitor") is a colony forming unit.
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CFU-Meg
CFU-Meg is a colony forming unit.
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Cluster of differentiation
The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells.
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Cobblestone
Cobblestone is a natural building material based on cobble-sized stones, and is used for pavement roads, streets, and buildings.
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Colony-forming unit
In microbiology, a colony-forming unit (CFU, cfu, Cfu) is a unit used to estimate the number of viable bacteria or fungal cells in a sample.
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CXCR4
C-X-C chemokine receptor type 4 (CXCR-4) also known as fusin or CD184 (cluster of differentiation 184) is a protein that in humans is encoded by the CXCR4 gene.
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DNA polymerase mu
DNA polymerase mu is a polymerase enzyme found in eukaryotes.
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Emperipolesis
In medicine, emperipolesis is the presence of an intact cell within the cytoplasm of another cell.
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Endoglin
Endoglin (ENG) is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex.
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Eosinophil
Eosinophils sometimes called eosinophiles or, less commonly, acidophils, are a variety of white blood cells and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates. Along with mast cells and basophils, they also control mechanisms associated with allergy and asthma. They are granulocytes that develop during hematopoiesis in the bone marrow before migrating into blood, after which they are terminally differentiated and do not multiply. These cells are eosinophilic or "acid-loving" due to their large acidophilic cytoplasmic granules, which show their affinity for acids by their affinity to coal tar dyes: Normally transparent, it is this affinity that causes them to appear brick-red after staining with eosin, a red dye, using the Romanowsky method. The staining is concentrated in small granules within the cellular cytoplasm, which contain many chemical mediators, such as eosinophil peroxidase, ribonuclease (RNase), deoxyribonucleases (DNase), lipase, plasminogen, and major basic protein. These mediators are released by a process called degranulation following activation of the eosinophil, and are toxic to both parasite and host tissues. In normal individuals, eosinophils make up about 1–3% of white blood cells, and are about 12–17 micrometres in size with bilobed nuclei. While they are released into the bloodstream as neutrophils are, eosinophils reside in tissue They are found in the medulla and the junction between the cortex and medulla of the thymus, and, in the lower gastrointestinal tract, ovary, uterus, spleen, and lymph nodes, but not in the lung, skin, esophagus, or some other internal organs under normal conditions. The presence of eosinophils in these latter organs is associated with disease. For instance, patients with eosinophilic asthma have high levels of eosinophils that lead to inflammation and tissue damage, making it more difficult for patients to breathe. Eosinophils persist in the circulation for 8–12 hours, and can survive in tissue for an additional 8–12 days in the absence of stimulation. Pioneering work in the 1980s elucidated that eosinophils were unique granulocytes, having the capacity to survive for extended periods of time after their maturation as demonstrated by ex-vivo culture experiments.
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Erythropoiesis
Erythropoiesis (from Greek 'erythro' meaning "red" and 'poiesis' meaning "to make") is the process which produces red blood cells (erythrocytes).
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Extramedullary hematopoiesis
Extramedullary hematopoiesis (EH) refers to hematopoiesis occurring outside of the medulla of the bone (bone marrow).
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Fc receptor
An Fc receptor is a protein found on the surface of certain cells – including, among others, B lymphocytes, follicular dendritic cells, natural killer cells, macrophages, neutrophils, eosinophils, basophils, human platelets, and mast cells – that contribute to the protective functions of the immune system.
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Femur
The femur (pl. femurs or femora) or thigh bone, is the most proximal (closest to the hip joint) bone of the leg in tetrapod vertebrates capable of walking or jumping, such as most land mammals, birds, many reptiles including lizards, and amphibians such as frogs.
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Flow cytometry
In biotechnology, flow cytometry is a laser- or impedance-based, biophysical technology employed in cell counting, cell sorting, biomarker detection and protein engineering, by suspending cells in a stream of fluid and passing them through an electronic detection apparatus.
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Granulocyte
Granulocytes are a category of white blood cells characterized by the presence of granules in their cytoplasm.
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Granulopoiesis
Granulopoiesis (or granulocytopoiesis) is production of granulocytes.
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Haematopoiesis
Haematopoiesis (from Greek αἷμα, "blood" and ποιεῖν "to make"; also hematopoiesis in American English; sometimes also haemopoiesis or hemopoiesis) is the formation of blood cellular components.
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Hamming distance
In information theory, the Hamming distance between two strings of equal length is the number of positions at which the corresponding symbols are different.
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Hematopoietic stem cell
Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells.
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Hematopoietic stem cell niche
Many human blood cells, such as red blood cells (RBCs), immune cells, and even platelets all originate from the same progenitor cell, the hematopoietic stem cell (HSC).
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Hematopoietic stem cell transplantation
Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood.
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Integrin
Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion.
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Integrin alpha M
Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3).
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Interleukin 7
Interleukin 7 (IL-7) is a protein that in humans is encoded by the IL7 gene.
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Irving Weissman
Irving Lerner "Irv" Weissman (born Great Falls, Montana, October 21, 1939) is a Professor of Pathology and Developmental Biology at Stanford University where he is the Director of the Stanford Institute of Stem Cell Biology and Regenerative Medicine along with Michael Longaker.
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LIG4
DNA ligase 4 is an enzyme that in humans is encoded by the LIG4 gene.
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Lineage markers
The lineage markers are characteristic molecules for cell lineages, e.g. cell surface markers, mRNAs, or internal proteins.
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List of human cell types derived from the germ layers
This is a list of cells in humans derived from the germ layers, which includes the ectoderm, mesoderm, and endoderm.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Lymphatic system
The lymphatic system is part of the vascular system and an important part of the immune system, comprising a network of lymphatic vessels that carry a clear fluid called lymph (from Latin, lympha meaning "water") directionally towards the heart.
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Lymphoblast
A lymphoblast is a modified naive lymphocyte that also looks completely different.
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Lymphocyte
A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system.
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Lymphopoiesis
Lymphopoiesis (lĭm'fō-poi-ē'sĭs) (or lymphocytopoiesis) is the generation of lymphocytes, one of the five types of white blood cell (WBC).
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Macrophage
Macrophages (big eaters, from Greek μακρός (makrós).
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Megakaryoblast
A megakaryoblast is a precursor cell to a promegakaryocyte, which in turn becomes a megakaryocyte during haematopoiesis.
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Megakaryocyte
A megakaryocyte (mega- + karyo- + -cyte, "large-nucleus cell") is a large bone marrow cell with a lobated nucleus responsible for the production of blood thrombocytes (platelets), which are necessary for normal blood clotting.
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Megakaryocyte–erythroid progenitor cell
The megakaryocyte–erythroid progenitor cell (or MEP, or hMEP to specify human) is a cell that gives rise to megakaryocytes and erythrocytes.
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Mesoderm
In all bilaterian animals, the mesoderm is one of the three primary germ layers in the very early embryo.
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Metamyelocyte
A metamyelocyte is a cell undergoing granulopoiesis, derived from a myelocyte, and leading to a band cell.
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Monoblast
Monoblasts are normally found in bone marrow and do not appear in the normal peripheral blood.
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Monocyte
Monocytes are a type of leukocyte, or white blood cell.
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Monocytopoiesis
Monocytopoiesis is the process which leads to the production of monocytes (and, subsequently, macrophages).
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Multipotentiality
Multipotentiality is an educational and psychological term referring to the ability and preference of a person, particularly one of strong intellectual or artistic curiosity, to excel in two or more different fields.
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Myeloblast
The myeloblast is a unipotent stem cell, which will differentiate into one of the effectors of the granulocyte series.
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Myelocyte
A myelocyte is a young cell of the granulocytic series, occurring normally in bone marrow (can be found in circulating blood when caused by certain diseases).
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Myeloid tissue
Myeloid tissue, in the bone marrow sense of the word myeloid (myelo- + -oid), is tissue of bone marrow, of bone marrow cell lineage, or resembling bone marrow, and myelogenous tissue (myelo- + -genous) is any tissue of, or arising from, bone marrow; in these senses the terms are usually used synonymously, as for example with chronic myeloid/myelogenous leukemia.
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Myelopoiesis
In hematology, myelopoiesis in the broadest sense of the term is the production of bone marrow and of all cells that arise from it, namely, all blood cells.
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Natural killer cell
Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system.
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Neutrophil
Neutrophils (also known as neutrocytes) are the most abundant type of granulocytes and the most abundant (40% to 70%) type of white blood cells in most mammals.
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Non-homologous end joining
Non-homologous end joining (NHEJ) is a pathway that repairs double-strand breaks in DNA.
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Non-homologous end-joining factor 1
Non-homologous end-joining factor 1 (NHEJ1), also known as Cernunnos or XRCC4-like factor (XLF), is a protein that in humans is encoded by the NHEJ1 gene.
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Nucleated red blood cell
With the exception of mammals, all vertebrate organisms have hemoglobin-containing cells in their blood and all of these red blood cells contain a nucleus.
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Osteoclast
An osteoclast is a type of bone cell that breaks down bone tissue.
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Pelvis
The pelvis (plural pelves or pelvises) is either the lower part of the trunk of the human body between the abdomen and the thighs (sometimes also called pelvic region of the trunk) or the skeleton embedded in it (sometimes also called bony pelvis, or pelvic skeleton).
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Platelet
Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.
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Proerythroblast
A proerythroblast (or rubriblast, or pronormoblast) is the earliest of four stages in development of the normoblast.
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Prolymphocyte
A prolymphocyte is a white blood cell with a certain state of cellular differentiation in lymphocytopoiesis.
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Promegakaryocyte
A promegakaryocyte is a precursor cell for a megakaryocyte, arising from a megakaryoblast.
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Promonocyte
A promonocyte (or premonocyte) is a cell arising from a monoblast and developing into a monocyte.
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Promyelocyte
A promyelocyte (or progranulocyte) is a granulocyte precursor, developing from the myeloblast and developing into the myelocyte.
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PTPRC
Protein tyrosine phosphatase, receptor type, C also known as PTPRC is an enzyme that, in humans, is encoded by the PTPRC gene.
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Red blood cell
Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.
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Reticulocyte
Reticulocytes are immature red blood cells, typically composing about 1% of the red blood cells in the human body.
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Severe combined immunodeficiency
Severe combined immunodeficiency, SCID, also known as alymphocytosis, Glanzmann–Riniker syndrome, severe mixed immunodeficiency syndrome, and thymic alymphoplasia, is a rare genetic disorder characterized by the disturbed development of functional T cells and B cells caused by numerous genetic mutations that result in heterogeneous clinical presentations.
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Side population
A side population (SP) in flow cytometry is a sub-population of cells that is distinct from the main population on the basis of the markers employed.
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Signaling lymphocytic activation molecule
Signaling lymphocytic activation molecule is a family of genes.
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SLAMF1
Signaling lymphocytic activation molecule 1 is a protein that in humans is encoded by the SLAMF1 gene.
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Spleen
The spleen is an organ found in virtually all vertebrates.
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Stanford University
Stanford University (officially Leland Stanford Junior University, colloquially the Farm) is a private research university in Stanford, California.
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Stem cell
Stem cells are biological cells that can differentiate into other types of cells and can divide to produce more of the same type of stem cells.
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Stem cell factor
Stem cell factor (also known as SCF, KIT-ligand, KL, or steel factor) is a cytokine that binds to the c-KIT receptor (CD117).
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Stem-cell niche
Stem-cell niche refers to a microenvironment, within the specific anatomic location where stem cells are found, which interacts with stem cells to regulate cell fate.
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Sternum
The sternum or breastbone is a long flat bone located in the center of the chest.
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Stromal cell-derived factor 1
The stromal cell-derived factor 1 (SDF1), also known as C-X-C motif chemokine 12 (CXCL12), is a chemokine protein that in humans is encoded by the CXCL12 gene on chromosome 10.
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Symbolic dynamics
In mathematics, symbolic dynamics is the practice of modeling a topological or smooth dynamical system by a discrete space consisting of infinite sequences of abstract symbols, each of which corresponds to a state of the system, with the dynamics (evolution) given by the shift operator.
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T cell
A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.
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Thrombopoiesis
Thrombopoiesis refers to the process of thrombocyte generation.
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Thymic nurse cell
Thymic nurse cells (TNCs) are large epithelial cells found in the cortex of thymus and also in cortico-medullary junction.
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Thymocyte
Thymocytes are hematopoietic progenitor cells present in the thymus.
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Thymus
The thymus is a specialized primary lymphoid organ of the immune system.
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Transforming growth factor
Transforming growth factor (sometimes referred to as Tumor growth factor, or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ.
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Umbilical cord
In placental mammals, the umbilical cord (also called the navel string, birth cord or funiculus umbilicalis) is a conduit between the developing embryo or fetus and the placenta.
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Venous blood
Venous blood is deoxygenated blood which travels from the peripheral vessels, through the venous system into the right atrium of the heart.
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Word sense
In linguistics, a word sense is one of the meanings of a word (some words have multiple meanings, some words have only one meaning).
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Bone marrow stem cell, Cellula haematopoietica praecursoria, Cellula haematopoietica precursoria, Cellula hematopoietica praecursoria, Cellula hematopoietica precursoria, Cellulae haematopoieticae praecursoriae, Cellulae haematopoieticae precursoriae, Cellulae hematopoieticae praecursoriae, Cellulae hematopoieticae precursoriae, Erythroid progenitor cells, Haematopoetic stem cell, Haematopoietic stem cell, Haemocytoblast, Hematopoetic stem cell, Hematopoetic stem cells, Hematopoietic cell growth factors, Hematopoietic progenitor cell, Hematopoietic stem cells, Hemoblast, Hemocytoblast, Hemocytoblasts, Hemopoietic cell, Hemopoietic stem cells, Hæmatopoietic stem cell, Hæmatopoietic stem cells, Multipotent hematopoietic stem cell, Multipotential hemopoietic stem cell, Myeloid progenitor cells, PHSC, PHSCs, Pluripotential hematopoietic stem cell, Pluripotential hematopoietic stem cells, Pluripotential hemopoeitic stem cell, Pluripotential hemopoietic stem cell, Pluripotential hemopoietic stem cells, Prolymphocytic.
References
[1] https://en.wikipedia.org/wiki/Hematopoietic_stem_cell
