109 relations: Alternative splicing, Amniotic sac, Amygdala, Amyotrophic lateral sclerosis, Astrocyte, Beta barrel, Betaherpesvirinae, Bone marrow suppression, Brain tumor, Burkitt's lymphoma, Cancer, Capsid, CD46, Central nervous system, Cerebrospinal fluid, Cervical cancer, Chiron Corporation, Cholesterol, Chronic fatigue syndrome, Cidofovir, Commensalism, Concatemer, Covalent bond, Cytokine, Dharam Ablashi, DNA polymerase, Encephalitis, Encephalopathy, Endometrium, Epstein–Barr virus, Equator, Female infertility, Fibromyalgia, Fibrosarcoma, Foscarnet, Ganciclovir, Glycogen synthase kinase, Glycoprotein, Glycosylphosphatidylinositol, Hashimoto's thyroiditis, Helicase–primase complex, Hematopoietic stem cell, Herpes simplex, Herpes simplex virus, Herpesvirales, Herpesviridae, Heterotetramer, Hippocampus, Histone deacetylase, HIV/AIDS, ..., Human herpesvirus 7, Human papillomavirus infection, Interleukin 8, International Committee on Taxonomy of Viruses, Kaposi's sarcoma, Kaposi's sarcoma-associated herpesvirus, Leukemia, Li–Fraumeni syndrome, Lipid raft, Lymphadenopathy, Lymphocyte, Lymphoma, Lymphoproliferative disorders, Medulloblastoma, MicroRNA, Mitogen-activated protein kinase, MMP9, Molecular and Cellular Probes, Multiple sclerosis, Myelin, Myelin basic protein, Myocarditis, National Institutes of Health, Natural killer cell, Neuroglia, Neurotropic virus, NF-κB, Olfaction, Olfactory ensheathing glia, Oligodendrocyte, Optic neuritis, Organ transplantation, Origin of replication, P53, Parahippocampal gyrus, Plasmid, Pneumonitis, Regular icosahedron, Ribozyme, Robert Gallo, Rolling circle replication, Roseola, Roseolovirus, Seattle, Serostatus, Sphingolipid, T cell, Telomere, Temporal lobe epilepsy, Thyroid, Tonsil, Valganciclovir, Vertically transmitted infection, Viral tegument, Virus, Western blot, World Health Organization, 37th parallel north, 42nd parallel north. Expand index (59 more) » « Shrink index
Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.
The amniotic sac, commonly called the bag of waters, sometimes the membranes, is the sac in which the fetus develops in amniotes.
The amygdala (plural: amygdalae; also corpus amygdaloideum; Latin from Greek, ἀμυγδαλή, amygdalē, 'Almond', 'tonsil') is one of two almond-shaped groups of nuclei located deep and medially within the temporal lobes of the brain in complex vertebrates, including humans.
Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND), and Lou Gehrig's disease, is a specific disease which causes the death of neurons controlling voluntary muscles.
Astrocytes (Astro from Greek astron.
A beta barrel is a beta-sheet that twists and coils to form a closed structure in which the first strand is hydrogen bonded to the last.
Betaherpesvirinae is a subfamily of viruses in the order Herpesvirales, in the family Herpesviridae.
Bone marrow suppression also known as myelotoxicity or myelosuppression, is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes).
A brain tumor occurs when abnormal cells form within the brain.
Burkitt lymphoma is a cancer of the lymphatic system, particularly B lymphocytes found in the germinal center.
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
A capsid is the protein shell of a virus.
CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene.
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
Cerebrospinal fluid (CSF) is a clear, colorless body fluid found in the brain and spinal cord.
Cervical cancer is a cancer arising from the cervix.
Chiron Corporation was an American multinational biotechnology firm based in Emeryville, California that was acquired by Novartis International AG on April 20, 2006.
Cholesterol (from the Ancient Greek chole- (bile) and stereos (solid), followed by the chemical suffix -ol for an alcohol) is an organic molecule.
Chronic fatigue syndrome (CFS), also referred to as myalgic encephalomyelitis (ME), is a medical condition characterized by long-term fatigue and other symptoms that limit a person's ability to carry out ordinary daily activities.
Cidofovir (brand name Vistide) is an injectable antiviral medication primarily used as a treatment for cytomegalovirus (CMV) retinitis (an infection of the retina of the eye) in people with AIDS.
Commensalism is a long term biological interaction (symbiosis) in which members of one species gain benefits while those of the other species are neither benefited nor harmed.
A concatemer is a long continuous DNA molecule that contains multiple copies of the same DNA sequence linked in series.
A covalent bond, also called a molecular bond, is a chemical bond that involves the sharing of electron pairs between atoms.
Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.
Dharam V. Ablashi (born October 8, 1931) is an American biomedical researcher born in India.
DNA polymerases are enzymes that synthesize DNA molecules from deoxyribonucleotides, the building blocks of DNA.
Encephalitis is inflammation of the brain.
Encephalopathy (from ἐγκέφαλος "brain" + πάθος "suffering") means any disorder or disease of the brain, especially chronic degenerative conditions.
The endometrium is the inner epithelial layer, along with its mucous membrane, of the mammalian uterus.
The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is one of eight known human herpesvirus types in the herpes family, and is one of the most common viruses in humans.
An equator of a rotating spheroid (such as a planet) is its zeroth circle of latitude (parallel).
Female infertility refers to infertility in female humans.
Fibromyalgia (FM) is a medical condition characterised by chronic widespread pain and a heightened pain response to pressure.
Fibrosarcoma (fibroblastic sarcoma) is a malignant mesenchymal tumour derived from fibrous connective tissue and characterized by the presence of immature proliferating fibroblasts or undifferentiated anaplastic spindle cells in a storiform pattern.
Foscarnet (sodium) is an antiviral medication which is primarily used to treat viral infections involving the Herpesviridae family.
Ganciclovir is an antiviral medication used to treat cytomegalovirus (CMV) infections.
Glycogen synthase kinase is an enzyme.
Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to amino acid side-chains.
Glycosylphosphatidylinositol, or glycophosphatidylinositol, or GPI in short, is a glycolipid that can be attached to the C-terminus of a protein during posttranslational modification.
Hashimoto's thyroiditis, also known as chronic lymphocytic thyroiditis and Hashimoto's disease, is an autoimmune disease in which the thyroid gland is gradually destroyed.
A helicase–primase complex (also helicase-primase, Hel/Prim, H-P or H/P) is a complex of enzymes including DNA helicase and DNA primase.
Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells.
Herpes simplex is a viral disease caused by the herpes simplex virus.
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as human herpesvirus 1 and 2 (HHV-1 and HHV-2), are two members of the herpesvirus family, Herpesviridae, that infect humans.
The Herpesvirales is an order of dsDNA viruses with eukaryotic hosts and enveloped virions, characterized by a common morphology.
Herpesviridae is a large family of DNA viruses that cause diseases in animals, including humans.
A heterotetramer is protein containing four non-covalently bound subunits, wherein the subunits are not all identical.
The hippocampus (named after its resemblance to the seahorse, from the Greek ἱππόκαμπος, "seahorse" from ἵππος hippos, "horse" and κάμπος kampos, "sea monster") is a major component of the brains of humans and other vertebrates.
Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups (O.
Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV).
Human herpesvirus 7 (HHV-7) is one of nine known members of the Herpesviridae family that infects humans.
Human papillomavirus infection is an infection by human papillomavirus (HPV).
Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells.
The International Committee on Taxonomy of Viruses (ICTV) authorizes and organizes the taxonomic classification of and the nomenclatures for viruses.
Kaposi's sarcoma (KS) is a type of cancer that can form masses in the skin, lymph nodes, or other organs.
Kaposi's sarcoma-associated herpesvirus (KSHV) is the ninth known human herpesvirus; its formal name according to the International Committee on Taxonomy of Viruses (ICTV) is HHV-8.
Leukemia, also spelled leukaemia, is a group of cancers that usually begin in the bone marrow and result in high numbers of abnormal white blood cells.
Li–Fraumeni syndrome is a rare, autosomal dominant, hereditary disorder that pre-disposes carriers to cancer development.
The plasma membranes of cells contain combinations of glycosphingolipids and protein receptors organised in glycolipoprotein microdomains termed lipid rafts.
Lymphadenopathy or adenopathy is disease of the lymph nodes, in which they are abnormal in size, number, or consistency.
A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system.
Lymphoma is a group of blood cancers that develop from lymphocytes (a type of white blood cell).
Lymphoproliferative disorders (LPDs) refer to several conditions in which lymphocytes are produced in excessive quantities.
Medulloblastoma is the most common type of pediatric malignant primary brain tumor (cancer), originating in the part of the brain that is towards the back and the bottom, on the floor of the skull, in the cerebellum, or posterior fossa.
A microRNA (abbreviated miRNA) is a small non-coding RNA molecule (containing about 22 nucleotides) found in plants, animals and some viruses, that functions in RNA silencing and post-transcriptional regulation of gene expression.
A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of protein kinase that is specific to the amino acids serine and threonine (i.e., a serine/threonine-specific protein kinase).
Matrix metallopeptidase 9 (MMP-9), also known as 92 kDa type IV collagenase, 92 kDa gelatinase or gelatinase B (GELB), is a matrixin, a class of enzymes that belong to the zinc-metalloproteinases family involved in the degradation of the extracellular matrix.
Molecular and Cellular Probes is a peer-reviewed scientific journal covering research on the location, diagnosis, and monitoring of inherited and infectious disease utilizing genomic, proteomic, and immunological techniques.
Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged.
Myelin is a lipid-rich substance that surrounds the axon of some nerve cells, forming an electrically insulating layer.
Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system.
Myocarditis, also known as inflammatory cardiomyopathy, is inflammation of the heart muscle.
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.
Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system.
Neuroglia, also called glial cells or simply glia, are non-neuronal cells in the central nervous system (brain and spinal cord) and the peripheral nervous system.
A neurotropic virus is a virus that is capable of infecting nerve cells.
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival.
Olfaction is a chemoreception that forms the sense of smell.
Olfactory ensheathing glia (OEG), also known as olfactory ensheathing cells (OECs) or olfactory ensheathing glial cells, are a type of macroglia (radial glia) found in the nervous system.
Oligodendrocytes, or oligodendroglia,.
Optic neuritis is a demyelinating inflammation of the optic nerve.
Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ.
The origin of replication (also called the replication origin) is a particular sequence in a genome at which replication is initiated.
Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice).
The parahippocampal gyrus (Syn. hippocampal gyrus) is a grey matter cortical region of the brain that surrounds the hippocampus and is part of the limbic system.
A plasmid is a small DNA molecule within a cell that is physically separated from a chromosomal DNA and can replicate independently.
Pneumonitis or pulmonitis is an inflammation of lung tissue due to factors other than microorganisms.
In geometry, a regular icosahedron is a convex polyhedron with 20 faces, 30 edges and 12 vertices.
Ribozymes (ribonucleic acid enzymes) are RNA molecules that are capable of catalyzing specific biochemical reactions, similar to the action of protein enzymes.
Robert Charles Gallo (born March 23, 1937) is an American biomedical researcher.
Rolling circle replication describes a process of unidirectional nucleic acid replication that can rapidly synthesize multiple copies of circular molecules of DNA or RNA, such as plasmids, the genomes of bacteriophages, and the circular RNA genome of viroids.
Roseola is an infectious disease caused by certain types of virus.
Roseolovirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Betaherpesvirinae.
Seattle is a seaport city on the west coast of the United States.
Serostatus refers to the presence or absence of a serological marker in the blood.
Sphingolipids are a class of lipids containing a backbone of sphingoid bases, a set of aliphatic amino alcohols that includes sphingosine.
A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.
A telomere is a region of repetitive nucleotide sequences at each end of a chromosome, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes.
Temporal lobe epilepsy (TLE) is a chronic disorder of the nervous system characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes.
The thyroid gland, or simply the thyroid, is an endocrine gland in the neck, consisting of two lobes connected by an isthmus.
Tonsils are collections of lymphoid tissue facing into the aerodigestive tract.
Valganciclovir, sold under the brandname Valcyte among others, is an antiviral medication used to treat cytomegalovirus (CMV) infection in those with HIV/AIDS or following organ transplant.
A vertically transmitted infection is an infection caused by pathogens (such as bacteria and viruses) that uses mother-to-child transmission, that is, transmission directly from the mother to an embryo, fetus, or baby during pregnancy or childbirth.
A viral tegument or tegument, more commonly known as a viral matrix, is a cluster of proteins that lines the space between the envelope and nucleocapsid of all herpesviruses.
A virus is a small infectious agent that replicates only inside the living cells of other organisms.
The western blot (sometimes called the protein immunoblot) is a widely used analytical technique used in molecular biology, immunogenetics and other molecular biology disciplines to detect specific proteins in a sample of tissue homogenate or extract.
The World Health Organization (WHO; French: Organisation mondiale de la santé) is a specialized agency of the United Nations that is concerned with international public health.
The 37th parallel north is a circle of latitude that is 37 degrees north of the Earth's equatorial plane.
The 42nd parallel north is a circle of latitude that is 42 degrees north of the Earth's equatorial plane.