176 relations: Acquired C1 esterase inhibitor deficiency, Acquired hemolytic anemia, Acute posthemorrhagic anemia, Adenosine deaminase, Adenosine deaminase deficiency, Agranulocytosis, Alpha-thalassemia, Anemia, Antibody, Aplastic anemia, Asplenia, Autoimmune hemolytic anemia, B cell, Bare lymphocyte syndrome, Basophilia, Bernard–Soulier syndrome, Beta thalassemia, Bleeding, Blood, C1-inhibitor, Chronic condition, Chronic granulomatous disease, Coagulation, Coagulopathy, Combined immunodeficiencies, Common variable immunodeficiency, Complement system, Congenital afibrinogenemia, Congenital dyserythropoietic anemia, Congenital hypoplastic anemia, Crisis, Cryoglobulinemia, Cytochrome b5 reductase, Diamond–Blackfan anemia, DiGeorge syndrome, Disseminated intravascular coagulation, Drug-induced autoimmune hemolytic anemia, Drug-induced nonautoimmune hemolytic anemia, Dysphagia, Enzyme, Eosinophilia, Eosinophilic granuloma, Epstein–Barr virus, Essential thrombocythemia, Evans syndrome, Factor IX, Factor VIII, Factor XI, Fanconi anemia, Folate deficiency, ..., Functional disorder, Glanzmann's thrombasthenia, Glucose-6-phosphate dehydrogenase, Glucose-6-phosphate dehydrogenase deficiency, Glutathione, Glycolysis, Gray platelet syndrome, Haemophilia A, Haemophilia B, Haemophilia C, Hand–Schüller–Christian disease, Health care, Hemoglobinopathy, Hemoglobinuria, Hemolysis, Hemolytic anemia, Hemolytic-uremic syndrome, Hemophagocytic lymphohistiocytosis, Henoch–Schönlein purpura, Hereditary elliptocytosis, Hereditary persistence of fetal hemoglobin, Hereditary spherocytosis, Hereditary stomatocytosis, Heredity, Hexokinase deficiency, Histiocytosis, Humoral immune deficiency, Hyper IgM syndrome, Hypergammaglobulinemia, Hyperimmunoglobulin E syndrome, Hypogammaglobulinemia, Hypoplasia, ICD-10, ICD-10 Chapter I: Certain infectious and parasitic diseases, ICD-10 Chapter II: Neoplasms, IgG deficiency, Immune system, Immune thrombocytopenic purpura, Immunodeficiency, Immunoglobulin A, Immunoglobulin E, Immunoglobulin G, Immunoglobulin M, International Statistical Classification of Diseases and Related Health Problems, Intrinsic factor, Iron deficiency, Iron-deficiency anemia, Isolated primary immunoglobulin M deficiency, Juvenile xanthogranuloma, Kostmann syndrome, Langerhans cell histiocytosis, Leukemia, Leukemoid reaction, Leukocytosis, List of ICD-9 codes 140–239: neoplasms, Lung, Lymph node, Lymphadenopathy, Lymphocyte function-associated antigen 1, Lymphocytopenia, Lymphocytosis, Major histocompatibility complex, May–Hegglin anomaly, Medical classification, Megaloblastic anemia, Methemoglobinemia, MHC class I, Microangiopathic hemolytic anemia, Monocytosis, Mononuclear phagocyte system, Multiple carboxylase deficiency, Myelophthisic anemia, Neutropenia, Neutrophil, Nezelof syndrome, Nonthrombocytopenic purpura, Nucleotide, Nutritional anemia, Paroxysmal cold hemoglobinuria, Paroxysmal nocturnal hemoglobinuria, Pelger–Huet anomaly, Plasmacytosis, Platelet, Plummer–Vinson syndrome, Polyclonal antibodies, Polycythemia, Proteinuria, Pure red cell aplasia, Purine nucleoside phosphorylase deficiency, Purpura, Purpura fulminans, Pyruvate kinase deficiency, Qualitative property, Reticular dysgenesis, Reticulohistiocytoma, Rosai–Dorfman disease, Sarcoidosis, Scurvy, Selective immunoglobulin A deficiency, Sepsis, Severe combined immunodeficiency, Sickle cell disease, Sickle cell trait, Sideroblastic anemia, Skin, Southeast Asian ovalocytosis, Spleen, Splenic infarction, Splenomegaly, Sulfhemoglobinemia, T cell, Thalassemia, Thrombocytopenia, Transcobalamin, Transient hypogammaglobulinemia of infancy, Triosephosphate isomerase deficiency, Vitamin B12, Vitamin B12 deficiency anemia, Von Willebrand disease, Warm antibody autoimmune hemolytic anemia, White blood cell, Wiskott–Aldrich syndrome, World Health Organization, X-linked agammaglobulinemia, X-linked lymphoproliferative disease, X-linked severe combined immunodeficiency. Expand index (126 more) » « Shrink index
Acquired C1 esterase inhibitor deficiency also known as "Acquired Angioedema" presents with symptoms indistinguishable from hereditary angioedema, but generally with onset after the fourth decade of life.
Acquired hemolytic anemia can be divided into immune and non-immune mediated forms of hemolytic anemia.
Acute posthemorrhagic anemia or acute blood loss anemia is a condition in which a person quickly loses a large volume of circulating hemoglobin.
Adenosine deaminase (also known as adenosine aminohydrolase, or ADA) is an enzyme involved in purine metabolism.
Adenosine deaminase deficiency (also called ADA deficiency or ADA-SCID) is an autosomal recessive metabolic disorder that causes immunodeficiency.
Agranulocytosis, also known as agranulosis or granulopenia, is an acute condition involving a severe and dangerous leukopenia (lowered white blood cell count), most commonly of neutrophils causing a neutropenia in the circulating blood.
Alpha-thalassemia (α-thalassemia, α-thalassaemia) is a form of thalassemia involving the genes HBA1 and HBA2.
Anemia is a decrease in the total amount of red blood cells (RBCs) or hemoglobin in the blood, or a lowered ability of the blood to carry oxygen.
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.
Aplastic anaemia is a rare disease in which the bone marrow and the hematopoietic stem cells that reside there are damaged.
Asplenia refers to the absence of normal spleen function and is associated with some serious infection risks.
Autoimmune hemolytic anemia (or autoimmune haemolytic anaemia; AIHA) occurs when antibodies directed against the person's own red blood cells (RBCs) cause them to burst (lyse), leading to an insufficient number of oxygen-carrying red blood cells in the circulation.
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.
Bare lymphocyte syndrome is a condition caused by mutations in certain genes of the major histocompatibility complex or involved with the processing and presentation of MHC molecules.
Basophilia is a condition derived from Basophils.
Bernard–Soulier syndrome (BSS), also called hemorrhagiparous thrombocytic dystrophy, is a rare autosomal recessive bleeding disorder that causes a deficiency of glycoprotein Ib (GpIb), the receptor for von Willebrand factor.
Beta thalassemias (β thalassemias) are a group of inherited blood disorders.
Bleeding, also known as hemorrhaging or haemorrhaging, is blood escaping from the circulatory system.
Blood is a body fluid in humans and other animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells.
C1-inhibitor (C1-inh, C1 esterase inhibitor) is a protease inhibitor belonging to the serpin superfamily.
A chronic condition is a human health condition or disease that is persistent or otherwise long-lasting in its effects or a disease that comes with time.
Chronic granulomatous disease (CGD) (also known as Bridges–Good syndrome, chronic granulomatous disorder, and Quie syndrome) is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds (most importantly the superoxide radical due to defective phagocyte NADPH oxidase) used to kill certain ingested pathogens.
Coagulation (also known as clotting) is the process by which blood changes from a liquid to a gel, forming a blood clot.
A bleeding disorder (coagulopathy) is a condition that affects the way the blood clots.
Combined immunodeficiencies (or combined immunity deficiency) are immunodeficiency disorders that involve multiple components of the immune system, including both humoral immunity and cell-mediated immunity.
Common variable immunodeficiency (CVID) is an immune disorder characterized by recurrent infections and low antibody levels, specifically in immunoglobulin (Ig) types IgG, IgM and IgA.
The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's cell membrane.
Congenital afibrinogenemia is a rare, genetically inherited blood fibrinogen disorder in which the blood does not clot normally due to the lack of fibrinogen, a blood protein necessary for coagulation.
Congenital dyserythropoietic anemia (CDA) is a rare blood disorder, similar to the thalassemias.
Congenital hypoplastic anemia (or constitutional aplastic anemia) is a type of aplastic anemia which is primarily due to a congenital disorder.
A crisis (from the Greek κρίσις - krisis; plural: "crises"; adjectival form: "critical") is any event that is going (or is expected) to lead to an unstable and dangerous situation affecting an individual, group, community, or whole society.
Cryoglobulinemia, cryoglobulinaemia, or cryoglobulinemic disease, is a medical condition in which the blood contains large amounts of cryoglobulins – proteins (mostly immunoglobulins themselves) that become insoluble at reduced temperatures.
Cytochrome-b5 reductase (also known as methemoglobin reductase) is a NADH-dependent enzyme that converts methemoglobin to hemoglobin.
Diamond–Blackfan anemia (DBA) is a congenital erythroid aplasia that usually presents in infancy.
DiGeorge syndrome, also known as 22q11.2 deletion syndrome, is a syndrome caused by the deletion of a small segment of chromosome 22.
Disseminated intravascular coagulation (DIC) is a condition in which blood clots form throughout the body, blocking small blood vessels.
Drug-induced autoimmune hemolytic anemia is a form of hemolytic anemia.
Drug-induced nonautoimmune hemolytic anemia is a form of hemolytic anemia.
Dysphagia is the medical term for the symptom of difficulty in swallowing.
Enzymes are macromolecular biological catalysts.
Eosinophilia is a condition in which the eosinophil count in the peripheral blood exceeds.
Eosinophilic granuloma is a form of Langerhans cell histiocytosis.
The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is one of eight known human herpesvirus types in the herpes family, and is one of the most common viruses in humans.
Essential thrombocythemia (ET) is a rare chronic blood condition characterised by the overproduction of platelets (thrombocytes) by megakaryocytes in the bone marrow.
Evans syndrome is an autoimmune disease in which an individual's immune system attacks their own red blood cells, white blood cells, and/or platelets.
Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1.
Factor VIII (FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor (AHF).
Factor XI or plasma thromboplastin antecedent is the zymogen form of factor XIa, one of the enzymes of the coagulation cascade.
Fanconi anaemia (FA) is a rare genetic disease resulting in impaired response to DNA damage.
Folate deficiency is a low level of folic acid and derivatives in the body.
A functional disorder is a medical condition that impairs normal functioning of bodily processes that remains largely undetected under examination, dissection or even under a microscope.
Glanzmann's thrombasthenia is an abnormality of the platelets.
Glucose-6-phosphate dehydrogenase (G6PD or G6PDH) is a cytosolic enzyme that catalyzes the chemical reaction This enzyme participates in the pentose phosphate pathway (see image), a metabolic pathway that supplies reducing energy to cells (such as erythrocytes) by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH).
Glucose-6-phosphate dehydrogenase deficiency (G6PDD) is an inborn error of metabolism that predisposes to red blood cell breakdown.
Glutathione (GSH) is an important antioxidant in plants, animals, fungi, and some bacteria and archaea.
Glycolysis (from glycose, an older term for glucose + -lysis degradation) is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+.
Gray platelet syndrome (GPS), or platelet alpha-granule deficiency, is a rare congenital autosomal recessive bleeding disorder caused by a reduction or absence of alpha-granules in blood platelets, and the release of proteins normally contained in these granules into the marrow, causing myelofibrosis.
Haemophilia A (or hemophilia A) is a genetic deficiency in clotting factor VIII, which causes increased bleeding and usually affects males.
Haemophilia B is a blood clotting disorder causing easy bruising and bleeding due to an inherited mutation of the gene for factor IX, and resulting in a deficiency of factor IX. It is less common than factor VIII deficiency (haemophilia A). Haemophilia B was first recognized as a distinct disease entity in 1952. It is also known by the eponym Christmas disease, named after Stephen Christmas, the first patient described with haemophilia B. In addition, the first report of its identification was published in the Christmas edition of the British Medical Journal.
Haemophilia C (also known as plasma thromboplastin antecedent (PTA) deficiency or Rosenthal syndrome) is a mild form of haemophilia affecting both sexes, due to factor XI deficiency.
Hand–Schüller–Christian disease is associated with multifocal Langerhans cell histiocytosis.
Health care or healthcare is the maintenance or improvement of health via the prevention, diagnosis, and treatment of disease, illness, injury, and other physical and mental impairments in human beings.
Hemoglobinopathy is a kind of genetic defect that results in abnormal structure of one of the globin chains of the hemoglobin molecule.
In medicine, hemoglobinuria or haemoglobinuria is a condition in which the oxygen transport protein hemoglobin is found in abnormally high concentrations in the urine.
Hemolysis or haemolysis, also known by several other names, is the rupturing (lysis) of red blood cells (erythrocytes) and the release of their contents (cytoplasm) into surrounding fluid (e.g. blood plasma).
Hemolytic anemia or haemolytic anaemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular, but usually in the spleen).
Hemolytic-uremic syndrome (HUS) is a disease characterized by a triad of hemolytic anemia (anemia caused by destruction of red blood cells), acute kidney failure (uremia), and a low platelet count (thrombocytopenia).
Hemophagocytic lymphohistiocytosis (HLH), also known as haemophagocytic lymphohistiocytosis (British spelling), and hemophagocytic or haemophagocytic syndrome, is an uncommon hematologic disorder seen more often in children than in adults.
Henoch–Schönlein purpura (HSP) also known as IgA vasculitis, anaphylactoid purpura, purpura rheumatica, and Schönlein–Henoch purpura, is a disease of the skin, mucous membranes, and sometimes other organs that most commonly affects children.
Hereditary elliptocytosis, also known as ovalocytosis, is an inherited blood disorder in which an abnormally large number of the patient's erythrocytes (i.e. red blood cells) are elliptical rather than the typical biconcave disc shape.
Hereditary persistence of fetal hemoglobin (HPFH, BrE: Hereditary persistence of foetal haemoglobin) is a benign condition in which significant fetal hemoglobin (hemoglobin F) production continues well into adulthood, disregarding the normal shutoff point after which only adult-type hemoglobin should be produced.
Hereditary spherocytosis (also known as Minkowski–Chauffard syndrome) is an abnormality of red blood cells, or erythrocytes.
Hereditary stomatocytosis describes a number of inherited autosomal dominant human conditions which affect the red blood cell, in which the membrane or outer coating of the cell 'leaks' sodium and potassium ions.
Heredity is the passing on of traits from parents to their offspring, either through asexual reproduction or sexual reproduction, the offspring cells or organisms acquire the genetic information of their parents.
Hexokinase deficiency is an anemia-causing condition associated with inadequate hexokinase.
In medicine, histiocytosis is an excessive number of histiocytes (tissue macrophages), and the term is also often used to refer to a group of rare diseases which share this sign as a characteristic.
Humoral immune deficiencies are conditions which cause impairment of humoral immunity, which can lead to immunodeficiency.
Hyper IgM syndromes is a group of primary immune deficiency disorders characterized by defective CD40 signaling; via B cells affecting class switch recombination (CSR) and somatic hypermutation.
Hypergammaglobulinemia is a medical condition with elevated levels of gamma globulin.
Hyperimmunoglobulinemia E syndrome (HIES), of which the autosomal dominant form is called Job's syndrome or Buckley syndrome, is a heterogeneous group of immune disorders.
Hypogammaglobulinemia is a type of primary immunodeficiency disease in which not enough gamma globulins exist in the blood (thus hypo- + gamma + globulin + -emia).
Hypoplasia (from Ancient Greek ὑπo- hypo-, "under" + πλάσις plasis, "formation"; adjective form hypoplastic) is underdevelopment or incomplete development of a tissue or organ.
ICD-10 is the 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD), a medical classification list by the World Health Organization (WHO).
ICD-10 is an international statistical classification used in health care and related industries.
ICD-10 is an international statistical classification used in health care and related industries.
IgG deficiency (Selective deficiency of immunoglobulin G) is a form of dysgammaglobulinemia where the proportional levels of the IgG isotype are reduced relative to other immunoglobulin isotypes.
The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.
Immune thrombocytopenia (ITP) is a type of thrombocytopenic purpura defined as isolated low platelet count (thrombocytopenia) with normal bone marrow and the absence of other causes of thrombocytopenia.
Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent.
Immunoglobulin A (IgA, also referred to as sIgA in its secretory form) is an antibody that plays a crucial role in the immune function of mucous membranes.
Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals.
Immunoglobulin G (IgG) is a type of antibody.
Immunoglobulin M (IgM) is one of several forms of antibody that are produced by vertebrates.
The International Classification of Diseases (ICD) is the international "standard diagnostic tool for epidemiology, health management and clinical purposes." Its full official name is International Statistical Classification of Diseases and Related Health Problems. The ICD is maintained by the World Health Organization (WHO), the directing and coordinating authority for health within the United Nations System.
Intrinsic factor (IF), also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells of the stomach.
Iron deficiency, or sideropaenia, is the state in which a body has not enough (or not qualitatively enough) iron to supply its eventual needs.
Iron-deficiency anemia is anemia caused by a lack of iron.
Isolated primary immunoglobulin M deficiency (or selective IgM immunodeficiency (SIgMD)) is a poorly defined dysgammaglobulinemia characterized by decreased levels of IgM while levels of other immunoglobulins are normal.
Juvenile xanthogranuloma (JXG) is a form of histiocytosis, classified as "non-Langerhans cell histiocytosis", or more specifically, "type 2".
Kostmann syndrome is a group of diseases that affect myelopoiesis, causing a congenital form of neutropenia (severe congenital neutropenia), usually without other physical malformations.
Langerhans cell histiocytosis (LCH) is a rare disease involving clonal proliferation of Langerhans cells, abnormal cells deriving from bone marrow and capable of migrating from skin to lymph nodes.
Leukemia, also spelled leukaemia, is a group of cancers that usually begin in the bone marrow and result in high numbers of abnormal white blood cells.
The term leukemoid reaction describes an increased white blood cell count, or leukocytosis, which is a physiological response to stress or infection (as opposed to a primary blood malignancy, such as leukemia).
Leukocytosis is white cells (the leukocyte count) above the normal range in the blood.
The lungs are the primary organs of the respiratory system in humans and many other animals including a few fish and some snails.
A lymph node or lymph gland is an ovoid or kidney-shaped organ of the lymphatic system, and of the adaptive immune system, that is widely present throughout the body.
Lymphadenopathy or adenopathy is disease of the lymph nodes, in which they are abnormal in size, number, or consistency.
Lymphocyte function-associated antigen 1 (LFA-1) is a cellular adhesion molecule found on lymphocytes.
Lymphocytopenia, or lymphopenia, is the condition of having an abnormally low level of lymphocytes in the blood.
Lymphocytosis is an increase in the number of lymphocytes in the blood.
The major histocompatibility complex (MHC) is a set of cell surface proteins essential for the acquired immune system to recognize foreign molecules in vertebrates, which in turn determines histocompatibility.
May–Hegglin anomaly (MHA), also known as Döhle leukocyte inclusions with giant platelets and macrothrombocytopenia with leukocyte inclusions, is a rare genetic disorder of the blood platelets that causes them to be abnormally large.
Medical classification, or medical coding, is the process of transforming descriptions of medical diagnoses and procedures into universal medical code numbers.
Megaloblastic anemia (or megaloblastic anaemia) is an anemia (of macrocytic classification) that results from inhibition of DNA synthesis during red blood cell production.
Methemoglobinemia is a condition caused by elevated levels of methemoglobin in the blood.
MHC class I molecules are one of two primary classes of major histocompatibility complex (MHC) molecules (the other being MHC class II) and are found on the cell surface of all nucleated cells in the bodies of jawed vertebrates.
In medicine (hematology), microangiopathic hemolytic anemia (MAHA) is a microangiopathic subgroup of hemolytic anemia (loss of red blood cells through destruction) caused by factors in the small blood vessels.
Monocytosis is an increase in the number of monocytes circulating in the blood.
In immunology, the mononuclear phagocyte system or mononuclear phagocytic system (MPS) (also known as the reticuloendothelial system or macrophage system) is a part of the immune system that consists of the phagocytic cells located in reticular connective tissue.
Multiple carboxylase deficiency is a form of metabolic disorder involving failures of carboxylation enzymes.
Myelophthisic anemia (or myelophthisis) is a severe type of anemia found in some people with diseases that affect the bone marrow.
Neutropenia or neutropaenia is an abnormally low concentration of neutrophils (a type of white blood cell) in the blood.
Neutrophils (also known as neutrocytes) are the most abundant type of granulocytes and the most abundant (40% to 70%) type of white blood cells in most mammals.
Nezelof syndrome (also known as Thymic dysplasia with normal immunoglobulins) is an autosomal recessive congenital immunodeficiency condition due to underdevelopment of the thymus.
Nonthrombocytopenic purpura is a type of purpura (red or purple skin discoloration) not associated with thrombocytopenia.
Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.
Nutritional anemia refers to the low concentration of hemoglobin due to poor diet.
Paroxysmal cold hemoglobinuria (PCH), also known as Donath-Landsteiner syndrome, is a disease of humans that is characterized by the sudden presence of hemoglobin in the urine (called hemoglobinuria), typically after exposure to cold temperatures.
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired, life-threatening disease of the blood characterized by destruction of red blood cells by the complement system, a part of the body's innate immune system.
Pelger–Huët anomaly (pronunciation) is a blood laminopathy associated with the lamin B receptor.
Plasmacytosis is a condition in which there is an unusually large proportion of plasma cells in tissues, exudates, or blood.
Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.
Plummer–Vinson syndrome (PVS), also called Paterson–Brown–Kelly syndrome or sideropenic dysphagia, is a rare disease characterized by difficulty in swallowing, iron-deficiency anemia, glossitis, cheilosis and esophageal webs.
Polyclonal antibodies (pAbs) are antibodies that are secreted by different B cell lineages within the body (whereas monoclonal antibodies come from a single cell lineage).
Polycythemia (also known as polycythaemia or polyglobulia) is a disease state in which the hematocrit (the volume percentage of red blood cells in the blood) is elevated.
Proteinuria is the presence of excess proteins in the urine.
Pure red cell aplasia (PRCA) or erythroblastopenia refers to a type of anemia affecting the precursors to red blood cells but not to white blood cells.
Purine nucleoside phosphorylase deficiency, often called PNP-deficiency, is a rare autosomal recessive metabolic disorder which results in immunodeficiency.
Purpura is a condition of red or purple discolored spots on the skin that do not blanch on applying pressure.
Purpura fulminans is an acute, often fatal, thrombotic disorder which manifests as blood spots, bruising and discolouration of the skin resulting from coagulation in small blood vessels within the skin and rapidly leads to skin necrosis and disseminated intravascular coagulation.
Pyruvate kinase deficiency is an inherited metabolic disorder of the enzyme pyruvate kinase which affects the survival of red blood cells.
Qualitative properties are properties that are observed and can generally not be measured with a numerical result.
Reticular dysgenesis (RD) is a rare, inherited autosomal recessive disease that results in immunodeficiency.
Reticulohistiocytoma is a cutaneous condition characterized by a solitary, firm, dermal skin lesion of less than 1 cm in diameter.
Rosai–Dorfman disease, originally known as sinus histiocytosis with massive lymphadenopathy, is a rare disorder of unknown cause that is characterized by abundant histiocytes in the lymph nodes or other locations throughout the body.
Sarcoidosis is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomas.
Scurvy is a disease resulting from a lack of vitamin C (ascorbic acid).
Selective immunoglobulin A (IgA) deficiency (SIgAD) is a genetic immunodeficiency, a type of hypogammaglobulinemia.
Sepsis is a life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs.
Severe combined immunodeficiency, SCID, also known as alymphocytosis, Glanzmann–Riniker syndrome, severe mixed immunodeficiency syndrome, and thymic alymphoplasia, is a rare genetic disorder characterized by the disturbed development of functional T cells and B cells caused by numerous genetic mutations that result in heterogeneous clinical presentations.
Sickle cell disease (SCD) is a group of blood disorders typically inherited from a person's parents.
Sickle cell trait describes a condition in which a person has one abnormal allele of the hemoglobin beta gene (is heterozygous), but does not display the severe symptoms of sickle-cell disease that occur in a person who has two copies of that allele (is homozygous).
Sideroblastic anemia or sideroachrestic anemia is a form of anemia in which the bone marrow produces ringed sideroblasts rather than healthy red blood cells (erythrocytes).
Skin is the soft outer tissue covering vertebrates.
Southeast Asian ovalocytosis is a blood disorder that is similar to, but distinct from hereditary elliptocytosis.
The spleen is an organ found in virtually all vertebrates.
Splenic infarction is a condition in which oxygen supply to the spleen is interrupted, leading to partial or complete infarction (tissue death due to oxygen shortage) in the organ.
Splenomegaly is an enlargement of the spleen.
Sulfhemoglobinemia (or sulfhaemoglobinaemia) is a rare condition in which there is excess sulfhemoglobin (SulfHb) in the blood.
A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.
Thalassemias are inherited blood disorders characterized by abnormal hemoglobin production.
Thrombocytopenia is a condition characterized by abnormally low levels of thrombocytes, also known as platelets, in the blood.
Transcobalamins are carrier proteins which bind cobalamin (B12).
Transient hypogammaglobulinemia of infancy is a form of hypogammaglobulinemia appearing after birth, leading to a reduction in the level of IgG, and also sometimes IgA and IgM.
Triosephosphate isomerase deficiency is a rare autosomal recessive metabolic disorder which was initially described in 1965.
Vitamin B12, also called cobalamin, is a water-soluble vitamin that is involved in the metabolism of every cell of the human body: it is a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism.
Vitamin B12 deficiency anemia, of which pernicious anemia is a type, is a disease in which not enough red blood cells are produced due to a deficiency of vitamin B12.
Von Willebrand disease (vWD) is the most common hereditary blood-clotting disorder in humans.
Warm antibody autoimmune hemolytic anemia (WAIHA) is the most common form of autoimmune hemolytic anemia.
White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.
Wiskott–Aldrich syndrome (WAS) is a rare X-linked recessive disease characterized by eczema, thrombocytopenia (low platelet count), immune deficiency, and bloody diarrhea (secondary to the thrombocytopenia).
The World Health Organization (WHO; French: Organisation mondiale de la santé) is a specialized agency of the United Nations that is concerned with international public health.
X-linked agammaglobulinemia (XLA) is a rare genetic disorder discovered in 1952 that affects the body's ability to fight infection.
X-linked lymphoproliferative disease (also known as "Duncan's disease" or "Purtilo syndrome") is a lymphoproliferative disorder.
X-linked severe combined immunodeficiency (X-SCID) is an immunodeficiency disorder in which the body produces very few T cells and NK cells.
ICD-10 Chapter D, ICD-10 Chapter II: Neoplasms; Chapter III: Diseases of the blood and blood-forming organs, and certain disorders involving the immune mechanism, ICD-10 Chapters C and D: Neoplasms, diseases of the blood and blood-forming organs, and certain disorders involving the immune mechanism.