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82 relations: Actin, Adenomatous polyposis coli, Alpha catenin, Apoptosis, ARF6, Arp2/3 complex, Beta-catenin, BRAF (gene), Breast cancer, C-Raf, Cadherin, Calmodulin, Calmodulin 1, Calponin, Calponin homology domain, Cancer, Carcinogenesis, CD44, CDC42, CDH1 (gene), Cell adhesion, Cell adhesion molecule, Cell cycle, Cell fate determination, Cell growth, Cell junction, Cell membrane, Cell migration, Cell nucleus, Cell signaling, Cellular differentiation, CLIP1, Colorectal cancer, Crosstalk (biology), Cytokinesis, Cytoplasm, Cytoskeleton, Epidermal growth factor, Eukaryote, Extracellular signal–regulated kinases, Filopodia, Gene, GTPase-activating protein, GTPase-activator protein for Ras-like GTPase, Hepatocellular carcinoma, Homeostasis, Hyperplasia, Insulin-like growth factor 1, IQ calmodulin-binding motif, IQ motif containing GTPase activating protein, ..., IQGAP2, Lung cancer, Malignancy, MAPK/ERK pathway, MCF-7, MDia1, Metastasis, Mitogen-activated protein kinase kinase, Mitosis, Morphology (biology), Motility, N-terminus, Nerve growth factor, Oncogene, Ovarian cancer, Platelet-derived growth factor, PRKACA, Protein, Protein domain, Protein–protein interaction, Proto-oncogene tyrosine-protein kinase Src, PTPRM, RAC1, Ras subfamily, Ras superfamily, Rho family of GTPases, S100B, Scaffold protein, Squamous cell carcinoma, Stomach cancer, Wnt signaling pathway, WW domain. Expand index (32 more) »
Actin
Actin is a family of globular multi-functional proteins that form microfilaments.
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Adenomatous polyposis coli
Adenomatous polyposis coli (APC) also known as deleted in polyposis 2.5 (DP2.5) is a protein that in humans is encoded by the APC gene.
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Alpha catenin
Alpha-catenin was suggested to function as a linking protein between cadherins and actin-containing filaments of the cytoskeleton.
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Apoptosis
Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.
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ARF6
ADP-ribosylation factor 6 (ARF6) is a member of the ADP ribosylation factor family of GTP-binding proteins.
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Arp2/3 complex
Arp2/3 complex is a seven-subunit protein complex that plays a major role in the regulation of the actin cytoskeleton.
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Beta-catenin
Catenin beta-1, also known as β-catenin, is a protein that in humans is encoded by the CTNNB1 gene.
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BRAF (gene)
BRAF is a human gene that encodes a protein called B-Raf.
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Breast cancer
Breast cancer is cancer that develops from breast tissue.
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C-Raf
RAF proto-oncogene serine/threonine-protein kinase, also known as proto-oncogene c-RAF or simply c-Raf or even Raf-1, is an enzyme that in humans is encoded by the RAF1 gene.
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Cadherin
Cadherins (named for "calcium-dependent adhesion") are a type of cell adhesion molecule (CAM) that is important in the formation of adherens junctions to bind cells with each other.
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Calmodulin
Calmodulin (CaM) (an abbreviation for calcium-modulated protein) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells.
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Calmodulin 1
Calmodulin 1 is a protein that in humans is encoded by the CALM1 gene.
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Calponin
Calponin is a calcium binding protein.
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Calponin homology domain
Calponin homology domain (or CH domain) is a family of actin binding domains found in both cytoskeletal proteins and signal transduction proteins.
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
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Carcinogenesis
Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells.
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CD44
The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration.
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CDC42
Cell division control protein 42 homolog, also known as Cdc42, is a protein involved in regulation of the cell cycle.
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CDH1 (gene)
Cadherin-1 also known as CAM 120/80 or epithelial cadherin (E-cadherin) or uvomorulin is a protein that in humans is encoded by the CDH1 gene.
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Cell adhesion
Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface.
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Cell adhesion molecule
Cell adhesion molecules (CAMs) are proteins located on the cell surface involved in binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion.
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Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.
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Cell fate determination
Within the field of developmental biology one goal is to understand how a particular cell (or embryo) develops into the final cell type (or organism), essentially how a cell's fate is determined.
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Cell growth
The term cell growth is used in the contexts of biological cell development and cell division (reproduction).
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Cell junction
A cell junction (or intercellular bridge) is a type of structure that exists within the tissue of some multicellular organisms, such as animals.
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Cell membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).
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Cell migration
Cell migration is a central process in the development and maintenance of multicellular organisms.
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Cell nucleus
In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.
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Cell signaling
Cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates all cell actions.
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Cellular differentiation
In developmental biology, cellular differentiation is the process where a cell changes from one cell type to another.
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CLIP1
CAP-GLY domain containing linker protein 1, also known as CLIP1, is a protein which in humans is encoded by the CLIP1 gene.
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Colorectal cancer
Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine).
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Crosstalk (biology)
Biological crosstalk refers to instances in which one or more components of one signal transduction pathway affects another.
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Cytokinesis
Cytokinesis is the part of the cell division process during which the cytoplasm of a single eukaryotic cell divides into two daughter cells.
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Cytoplasm
In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.
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Cytoskeleton
A cytoskeleton is present in all cells of all domains of life (archaea, bacteria, eukaryotes).
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Epidermal growth factor
Epidermal growth factor (EGF) stimulates cell growth and differentiation by binding to its receptor, EGFR.
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Eukaryote
Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).
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Extracellular signal–regulated kinases
In molecular biology, extracellular signal–regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that are involved in functions including the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.
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Filopodia
Filopodia (also microspikes) are slender cytoplasmic projections that extend beyond the leading edge of lamellipodia in migrating cells.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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GTPase-activating protein
GTPase-activating proteins or GTPase-accelerating proteins (GAPs) are a family of regulatory proteins whose members can bind to activated G proteins and stimulate their GTPase activity, with the result of terminating the signaling event.
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GTPase-activator protein for Ras-like GTPase
GTPase-activator protein for Ras-like GTPase is a family of evolutionarily related proteins.
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Hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults, and is the most common cause of death in people with cirrhosis.
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Homeostasis
Homeostasis is the tendency of organisms to auto-regulate and maintain their internal environment in a stable state.
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Hyperplasia
Hyperplasia (from ancient Greek ὑπέρ huper, "over" + πλάσις plasis, "formation"), or hypergenesis, is an increase in the amount of organic tissue that results from cell proliferation.
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Insulin-like growth factor 1
Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a protein that in humans is encoded by the IGF1 gene.
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IQ calmodulin-binding motif
The IQ calmodulin-binding motif is an amino acid sequence motif containing the following sequence.
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IQ motif containing GTPase activating protein
IQ motif containing GTPase activating protein (IQGAP) is a carrier protein.
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IQGAP2
Ras GTPase-activating-like protein IQGAP2 is an enzyme that in humans is encoded by the IQGAP2 gene.
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Lung cancer
Lung cancer, also known as lung carcinoma, is a malignant lung tumor characterized by uncontrolled cell growth in tissues of the lung.
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Malignancy
Malignancy is the tendency of a medical condition to become progressively worse.
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MAPK/ERK pathway
The MAPK/ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the surface of the cell to the DNA in the nucleus of the cell.
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MCF-7
MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old Caucasian woman.
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MDia1
mDia1 (also known as Dia1, Drf1 for Diaphanous-related formin-1, Diaph1, KIAA4062, p140mDia, mKIAA4062, or D18Wsu154e) is a member of the protein family called the formins and is a Rho effector.
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Metastasis
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.
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Mitogen-activated protein kinase kinase
Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a kinase enzyme which phosphorylates mitogen-activated protein kinase (MAPK).
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Mitosis
In cell biology, mitosis is a part of the cell cycle when replicated chromosomes are separated into two new nuclei.
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Morphology (biology)
Morphology is a branch of biology dealing with the study of the form and structure of organisms and their specific structural features.
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Motility
Motility is the ability of an organism to move independently, using metabolic energy.
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N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
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Nerve growth factor
Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival of certain target neurons.
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Oncogene
An oncogene is a gene that has the potential to cause cancer.
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Ovarian cancer
Ovarian cancer is a cancer that forms in or on an ovary.
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Platelet-derived growth factor
Platelet-derived growth factor (PDGF) is one of numerous growth factors that regulate cell growth and division.
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PRKACA
The catalytic subunit α of protein kinase A is a key regulatory enzyme that in humans is encoded by the PRKACA gene.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein domain
A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Proto-oncogene tyrosine-protein kinase Src
Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src or simply c-Src, is a non-receptor tyrosine kinase protein that in humans is encoded by the SRC gene.
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PTPRM
Receptor-type tyrosine-protein phosphatase mu is an enzyme that in humans is encoded by the PTPRM gene.
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RAC1
Rac1, also known as Ras-related C3 botulinum toxin substrate 1, is a protein found in human cells.
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Ras subfamily
Ras is a family of related proteins which is expressed in all animal cell lineages and organs.
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Ras superfamily
The Ras superfamily is a protein superfamily of small GTPases.
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Rho family of GTPases
The Rho family of GTPases is a family of small (~21 kDa) signaling G proteins, and is a subfamily of the Ras superfamily.
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S100B
S100 calcium-binding protein B (S100B) is a protein of the S-100 protein family.
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Scaffold protein
In biology, scaffold proteins are crucial regulators of many key signalling pathways.
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Squamous cell carcinoma
Squamous cell carcinomas, also known as epidermoid carcinoma are a number of different types of cancer that result from squamous cells.
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Stomach cancer
Stomach cancer, also known as gastric cancer, is cancer developing from the lining of the stomach.
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Wnt signaling pathway
The Wnt signaling pathways are a group of signal transduction pathways made of proteins that pass signals into a cell through cell surface receptors.
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WW domain
The WW domain, (also known as the rsp5-domain or WWP repeating motif) is a modular protein domain that mediates specific interactions with protein ligands.
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References
[1] https://en.wikipedia.org/wiki/IQGAP1
