Faster access than browser!
33 relations: Alternative splicing, Antisense therapy, Biogen, Blood plasma, Central nervous system, Cerebrospinal fluid, Cision, Cold Spring Harbor Laboratory, Cytochrome P450, Drug discovery, European Medicines Agency, European Union, Intrathecal administration, Ionis Pharmaceuticals, List price, Marketing authorization, Mutation, New Drug Application, Oligonucleotide, Orphan drug, Priority review, Pulmonary aspiration, Scoliosis, SMN1, SMN2, Spinal muscular atrophy, Survival of motor neuron, The New York Times, Thiophosphate, Thrombocytopenia, Unified atomic mass unit, United States, University of Massachusetts Medical School.
Alternative splicing
Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.
New!!: Nusinersen and Alternative splicing · See more »
Antisense therapy
Antisense therapy is a form of treatment for genetic disorders or infections.
New!!: Nusinersen and Antisense therapy · See more »
Biogen
Biogen, Inc. (previously known as Biogen Idec) is an American multinational biotechnology company based in Cambridge, Massachusetts, specializing in the discovery, development, and delivery of therapies for the treatment of neurodegenerative, hematologic, and autoimmune diseases to patients worldwide.
New!!: Nusinersen and Biogen · See more »
Blood plasma
Blood plasma is a yellowish coloured liquid component of blood that normally holds the blood cells in whole blood in suspension; this makes plasma the extracellular matrix of blood cells.
New!!: Nusinersen and Blood plasma · See more »
Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
New!!: Nusinersen and Central nervous system · See more »
Cerebrospinal fluid
Cerebrospinal fluid (CSF) is a clear, colorless body fluid found in the brain and spinal cord.
New!!: Nusinersen and Cerebrospinal fluid · See more »
Cision
Cision Ltd. is a public relations and earned media software company and services provider.
New!!: Nusinersen and Cision · See more »
Cold Spring Harbor Laboratory
Cold Spring Harbor Laboratory (CSHL) is a private, non-profit institution with research programs focusing on cancer, neuroscience, plant genetics, genomics, and quantitative biology.
New!!: Nusinersen and Cold Spring Harbor Laboratory · See more »
Cytochrome P450
Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.
New!!: Nusinersen and Cytochrome P450 · See more »
Drug discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
New!!: Nusinersen and Drug discovery · See more »
European Medicines Agency
The European Medicines Agency (EMA) is a European Union agency for the evaluation of medicinal products.
New!!: Nusinersen and European Medicines Agency · See more »
European Union
The European Union (EU) is a political and economic union of EUnum member states that are located primarily in Europe.
New!!: Nusinersen and European Union · See more »
Intrathecal administration
Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF) and is useful in spinal anaesthesia, chemotherapy, or pain management applications.
New!!: Nusinersen and Intrathecal administration · See more »
Ionis Pharmaceuticals
Ionis Pharmaceuticals (known as Isis Pharmaceuticals until December 2015) is a publicly traded pharmaceutical company based in Carlsbad, California, United States.
New!!: Nusinersen and Ionis Pharmaceuticals · See more »
List price
The list price, also known as the manufacturer's suggested retail price (MSRP), or the recommended retail price (RRP), or the suggested retail price (SRP), of a product is the price at which the manufacturer recommends that the retailer sell the product.
New!!: Nusinersen and List price · See more »
Marketing authorization
Process of reviewing and assessing the dossier to support a medicinal product in view of its marketing (also called licensing, registration, approval, etc.), finalized by granting of a document also called marketing authorization (MA) (equivalent: product license).
New!!: Nusinersen and Marketing authorization · See more »
Mutation
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.
New!!: Nusinersen and Mutation · See more »
New Drug Application
The Food and Drug Administration's New Drug Application (NDA) is the vehicle in the United States through which drug sponsors formally propose that the FDA approve a new pharmaceutical for sale and marketing.
New!!: Nusinersen and New Drug Application · See more »
Oligonucleotide
Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics.
New!!: Nusinersen and Oligonucleotide · See more »
Orphan drug
An orphan drug is a pharmaceutical agent that has been developed specifically to treat a rare medical condition, the condition itself being referred to as an orphan disease.
New!!: Nusinersen and Orphan drug · See more »
Priority review
Priority review is a mechanism used by the United States Food and Drug Administration (FDA) to expedite the review process for drugs that are expected to have a particularly great impact on the treatment of a disease.
New!!: Nusinersen and Priority review · See more »
Pulmonary aspiration
Pulmonary aspiration is the entry of material (such as pharyngeal secretions, food or drink, or stomach contents) from the oropharynx or gastrointestinal tract into the larynx (voice box) and lower respiratory tract (the portions of the respiratory system from the trachea—i.e., windpipe—to the lungs).
New!!: Nusinersen and Pulmonary aspiration · See more »
Scoliosis
Scoliosis is a medical condition in which a person's spine has a sideways curve.
New!!: Nusinersen and Scoliosis · See more »
SMN1
Survival of motor neuron 1 (SMN1), also known as component of gems 1 or GEMIN1, is a gene that encodes the SMN protein in humans.
New!!: Nusinersen and SMN1 · See more »
SMN2
Survival of motor neuron 2 (SMN2) is a gene that encodes the SMN protein (full and truncated) in humans.
New!!: Nusinersen and SMN2 · See more »
Spinal muscular atrophy
Spinal muscular atrophy (SMA) is a rare neuromuscular disorder characterised by loss of motor neurons and progressive muscle wasting, often leading to early death.
New!!: Nusinersen and Spinal muscular atrophy · See more »
Survival of motor neuron
Survival of motor neuron or survival motor neuron (SMN) is a protein that in humans is encoded by the SMN1 and SMN2 genes.
New!!: Nusinersen and Survival of motor neuron · See more »
The New York Times
The New York Times (sometimes abbreviated as The NYT or The Times) is an American newspaper based in New York City with worldwide influence and readership.
New!!: Nusinersen and The New York Times · See more »
Thiophosphate
Thiophosphates (or phosphorothioates, PS) are chemical compounds and anions with the general chemical formula PS4−xO (x.
New!!: Nusinersen and Thiophosphate · See more »
Thrombocytopenia
Thrombocytopenia is a condition characterized by abnormally low levels of thrombocytes, also known as platelets, in the blood.
New!!: Nusinersen and Thrombocytopenia · See more »
Unified atomic mass unit
The unified atomic mass unit or dalton (symbol: u, or Da) is a standard unit of mass that quantifies mass on an atomic or molecular scale (atomic mass).
New!!: Nusinersen and Unified atomic mass unit · See more »
United States
The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.
New!!: Nusinersen and United States · See more »
University of Massachusetts Medical School
The University of Massachusetts Medical School (UMMS) is one of five campuses of the University of Massachusetts (UMass) system.
New!!: Nusinersen and University of Massachusetts Medical School · See more »
Redirects here:
IONIS-SMNRx, ISIS-SMNRx, SMNRx, Spinraza.
References
[1] https://en.wikipedia.org/wiki/Nusinersen
