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Immortalised cell line

Index Immortalised cell line

An immortalized cell line is a population of cells from a multicellular organism which would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division. [1]

44 relations: A549 cell, Antibody, ATCC (company), B cell, Biochemistry, Biotechnology, Cancer, Cell (biology), Cell biology, Cell Biology International, Cell cycle, Cellosaurus, Cellular senescence, Cervical cancer, Chromosome, Clone (cell biology), Fibroblast, Gene expression, HEK 293 cells, HeLa, Henrietta Lacks, Hoechst stain, Human, Hybridoma technology, In vitro, Jurkat cells, Kidney, List of breast cancer cell lines, Lung, Mammal, Medical research, Multicellular organism, Multiple myeloma, Mutagenesis, Mutation, Nature Methods, Protein, Somatic cell, Stem cell, T cell, Telomerase, Toxicity, Vero cell, 3T3 cells.

A549 cell

A549 cells are adenocarcinomic human alveolar basal epithelial cells, and constitute a cell line that was first developed in 1972 by D. J. Giard, et al.

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Antibody

An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.

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ATCC (company)

ATCC or the American Type Culture Collection is a nonprofit organization which collects, stores, and distributes standard reference microorganisms, cell lines and other materials for research and development.

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B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.

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Biochemistry

Biochemistry, sometimes called biological chemistry, is the study of chemical processes within and relating to living organisms.

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Biotechnology

Biotechnology is the broad area of science involving living systems and organisms to develop or make products, or "any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use" (UN Convention on Biological Diversity, Art. 2).

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Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Cell (biology)

The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.

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Cell biology

Cell biology (also called cytology, from the Greek κυτος, kytos, "vessel") is a branch of biology that studies the structure and function of the cell, the basic unit of life.

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Cell Biology International

Cell Biology International is a peer-reviewed scientific journal published by Portland Press for the International Federation for Cell Biology.

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Cell cycle

The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.

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Cellosaurus

Cellosaurus is an on-line knowledge resource on cell lines.

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Cellular senescence

Cellular senescence is one phenomenon by which normal cells cease to divide.

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Cervical cancer

Cervical cancer is a cancer arising from the cervix.

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Chromosome

A chromosome (from Ancient Greek: χρωμόσωμα, chromosoma, chroma means colour, soma means body) is a DNA molecule with part or all of the genetic material (genome) of an organism.

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Clone (cell biology)

A clone is a group of identical cells that share a common ancestry, meaning they are derived from the same cell.

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Fibroblast

A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing.

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Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.

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HEK 293 cells

Human embryonic kidney cells 293, also often referred to as HEK 293, HEK-293, 293 cells, or less precisely as HEK cells, are a specific cell line originally derived from human embryonic kidney cells grown in tissue culture.

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HeLa

HeLa (also Hela or hela) is a cell type in an immortal cell line used in scientific research.

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Henrietta Lacks

Henrietta Lacks (born Loretta Pleasant; August 1, 1920 – October 4, 1951) Note: Some sources report her birthday as August 2, 1920, vs.

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Hoechst stain

Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA.

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Human

Humans (taxonomically Homo sapiens) are the only extant members of the subtribe Hominina.

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Hybridoma technology

Hybridoma technology is a method for producing large numbers of identical antibodies (also called monoclonal antibodies).

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In vitro

In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.

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Jurkat cells

Jurkat cells are an immortalized line of human T lymphocyte cells that are used to study acute T cell leukemia, T cell signaling, and the expression of various chemokine receptors susceptible to viral entry, particularly HIV.

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Kidney

The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.

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List of breast cancer cell lines

Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease.

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Lung

The lungs are the primary organs of the respiratory system in humans and many other animals including a few fish and some snails.

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Mammal

Mammals are the vertebrates within the class Mammalia (from Latin mamma "breast"), a clade of endothermic amniotes distinguished from reptiles (including birds) by the possession of a neocortex (a region of the brain), hair, three middle ear bones, and mammary glands.

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Medical research

Biomedical research (or experimental medicine) encompasses a wide array of research, extending from "basic research" (also called bench science or bench research), – involving fundamental scientific principles that may apply to a ''preclinical'' understanding – to clinical research, which involves studies of people who may be subjects in clinical trials.

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Multicellular organism

Multicellular organisms are organisms that consist of more than one cell, in contrast to unicellular organisms.

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Multiple myeloma

Multiple myeloma, also known as plasma cell myeloma, is a cancer of plasma cells, a type of white blood cell normally responsible for producing antibodies.

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Mutagenesis

Mutagenesis is a process by which the genetic information of an organism is changed, resulting in a mutation.

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Mutation

In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.

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Nature Methods

Nature Methods is a monthly peer-reviewed scientific journal covering new scientific techniques.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Somatic cell

A somatic cell (from the Greek σῶμα sôma, meaning "body") or vegetal cell is any biological cell forming the body of an organism; that is, in a multicellular organism, any cell other than a gamete, germ cell, gametocyte or undifferentiated stem cell.

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Stem cell

Stem cells are biological cells that can differentiate into other types of cells and can divide to produce more of the same type of stem cells.

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T cell

A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.

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Telomerase

Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres.

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Toxicity

Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism.

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Vero cell

Vero cells are a lineage of cells used in cell cultures.

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3T3 cells

3T3 cells come from a cell line established in 1962 by two scientists then at the Department of Pathology in the New York University School of Medicine, George Todaro and Howard Green.

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Cell line, Cell lines, Immortalise, Immortalized cell line.

References

[1] https://en.wikipedia.org/wiki/Immortalised_cell_line

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