26 relations: Amino acid, Antibody, Antigen, B cell, B-cell lymphoma, Bence Jones protein, Camelid, Charles Janeway, Chondrichthyes, Chromosome 2, Chromosome 22, Evolution of tetrapods, IGK@, IGL@, Immunoglobulin domain, Immunoglobulin heavy chain, Immunohistochemistry, Lymphoid hyperplasia, Monoclonal antibody, Multiple myeloma, Neoplasm, Peptide, Shark, Teleost, Tetrapod, Vertebrate.
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.
In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism.
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.
The B-cell lymphomas are types of lymphoma affecting B cells.
A Bence Jones protein is a monoclonal globulin protein or immunoglobulin light chain found in the urine, with a molecular weight of 22-24 kDa.
Camelids are members of the biological family Camelidae, the only currently living family in the suborder Tylopoda.
Charles Alderson Janeway, Jr. (1943–2003) was a noted immunologist.
Chondrichthyes (from Greek χονδρ- chondr- 'cartilage', ἰχθύς ichthys 'fish') is a class that contains the cartilaginous fishes: they are jawed vertebrates with paired fins, paired nares, scales, a heart with its chambers in series, and skeletons made of cartilage rather than bone.
Chromosome 2 is one of the 23 pairs of chromosomes in humans.
Chromosome 22 is one of the 23 pairs of chromosomes in human cells.
The evolution of tetrapods began about 400 million years ago in the Devonian Period with the earliest tetrapods evolved from lobe-finned fishes.
Immunoglobulin kappa locus, also known as IGK@, is a region on human chromosome 2 that contains genes for the kappa (κ) light chains of antibodies (or immunoglobulins).
Immunoglobulin lambda locus, also known as IGL@, is a region on human chromosome 22 that contains genes for the lambda light chains of antibodies (or immunoglobulins).
The immunoglobulin domain is a type of protein domain that consists of a 2-layer sandwich of 7-9 antiparallel β-strands arranged in two β-sheets with a Greek key topology, consisting of about 125 amino acids.
The immunoglobulin heavy chain (IgH) is the large polypeptide subunit of an antibody (immunoglobulin).
Immunohistochemistry (IHC) involves the process of selectively imaging antigens (proteins) in cells of a tissue section by exploiting the principle of antibodies binding specifically to antigens in biological tissues.
Lymphoid hyperplasia is the rapid growth proliferation of normal cells that resemble lymph tissue.
Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell.
Multiple myeloma, also known as plasma cell myeloma, is a cancer of plasma cells, a type of white blood cell normally responsible for producing antibodies.
Neoplasia is a type of abnormal and excessive growth of tissue.
Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.
Sharks are a group of elasmobranch fish characterized by a cartilaginous skeleton, five to seven gill slits on the sides of the head, and pectoral fins that are not fused to the head.
The teleosts or Teleostei (Greek: teleios, "complete" + osteon, "bone") are by far the largest infraclass in the class Actinopterygii, the ray-finned fishes, and make up 96% of all extant species of fish.
The superclass Tetrapoda (from Greek: τετρα- "four" and πούς "foot") contains the four-limbed vertebrates known as tetrapods; it includes living and extinct amphibians, reptiles (including dinosaurs, and its subgroup birds) and mammals (including primates, and all hominid subgroups including humans), as well as earlier extinct groups.
Vertebrates comprise all species of animals within the subphylum Vertebrata (chordates with backbones).
Antibody light chain, Immunoglobin light chain, Immunoglobulin kappa-chains, Immunoglobulin km allotypes, Immunoglobulin lambda-chains, Immunoglobulin light chains, Immunoglobulin light-chains, Kappa and lambda light chain, Kappa-chain immunoglobulin, Kappachain immunoglobulin, Lambda light chain, Lambda light chain levels, Monoclonal light chain, Monoclonal light chains.