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10 relations: Agonist, Drug, EC50, Inverse agonist, Naloxone, Partial agonist, Potency (pharmacology), Receptor (biochemistry), Superagonist, 2,5-Dimethoxy-4-iodoamphetamine.
Agonist
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
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Drug
A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.
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EC50
Half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time.
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Inverse agonist
In the field of pharmacology, an inverse agonist is an agent that binds to the same receptor as an agonist but induces a pharmacological response opposite to that agonist.
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Naloxone
Naloxone, sold under the brandname Narcan among others, is a medication used to block the effects of opioids, especially in overdose.
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Partial agonist
In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.
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Potency (pharmacology)
In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.
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Receptor (biochemistry)
In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.
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Superagonist
In the field of pharmacology, a superagonist is a type of agonist that is capable of producing a maximal response greater than the endogenous agonist for the target receptor, and thus has an efficacy of more than 100%.
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2,5-Dimethoxy-4-iodoamphetamine
2,5-Dimethoxy-4-iodoamphetamine (DOI) is a psychedelic drug and a substituted amphetamine.
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Efficacy (pharmacology), Intrinsic efficacy, Maximal efficacy, Relative transactivational capacities, Relative transactivational capacity.
