Iodocholesterol

Iodocholesterol, or 19-iodocholesterol, also as iodocholesterol (131I) (INN) and NP-59, is a derivative of cholesterol with an iodine atom in the C19 position and a radiopharmaceutical. ^[1]

Adrenal cortex

The adrenal cortex is the outer region and also the largest part of the adrenal gland.

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Adrenalectomy (Latin root Ad "near/at" + renal "related to the kidneys" + Greek ‑ectomy “out-cutting”; sometimes written as ADX for the procedure or resulting state) is the surgical removal of one (unilateral) or both (bilateral) adrenal glands.

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Atom

Atoms are the basic particles of the chemical elements.

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Cholesterol

Cholesterol is the principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. Iodocholesterol and Cholesterol are Cholestanes.

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Cushing's syndrome

Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol.

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Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

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Hyperaldosteronism

Hyperaldosteronism is a medical condition wherein too much aldosterone is produced.

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International nonproprietary name

An international nonproprietary name (INN) is an official generic and nonproprietary name given to a pharmaceutical drug or an active ingredient.

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Iodine

Iodine is a chemical element; it has symbol I and atomic number 53.

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Iodine-125

Iodine-125 (125I) is a radioisotope of iodine which has uses in biological assays, nuclear medicine imaging and in radiation therapy as brachytherapy to treat a number of conditions, including prostate cancer, uveal melanomas, and brain tumors.

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Iodine-131

Iodine-131 (131I, I-131) is an important radioisotope of iodine discovered by Glenn Seaborg and John Livingood in 1938 at the University of California, Berkeley.

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Pheochromocytoma

Pheochromocytoma is a rare tumor of the adrenal medulla composed of chromaffin cells and is part of the paraganglioma (PGL) family of tumors, being defined as an intra-adrenal PGL.

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Radioactive tracer

A radioactive tracer, radiotracer, or radioactive label is a synthetic derivative of a natural compound in which one or more atoms have been replaced by a radionuclide (a radioactive atom). Iodocholesterol and radioactive tracer are Radiopharmaceuticals.

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Radionuclide

A radionuclide (radioactive nuclide, radioisotope or radioactive isotope) is a nuclide that has excess numbers of either neutrons or protons, giving it excess nuclear energy, and making it unstable.

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Radiopharmaceutical

Radiopharmaceuticals, or medicinal radiocompounds, are a group of pharmaceutical drugs containing radioactive isotopes. Iodocholesterol and Radiopharmaceutical are Radiopharmaceuticals.

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References

[1] https://en.wikipedia.org/wiki/Iodocholesterol

Also known as 19-Iodocholesterol, Iodocholesterol (125I), Iodocholesterol (131I), NP-59.

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