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Isopentenyl pyrophosphate

Index Isopentenyl pyrophosphate

Isopentenyl pyrophosphate (IPP, isopentenyl diphosphate, or IDP) is an isoprenoid precursor. [1]

19 relations: Acetyl-CoA, Apicomplexa, Bacteria, Dimethylallyl pyrophosphate, Dimethylallyltranstransferase, Geranyl pyrophosphate, Isomer, Isopentenyl-diphosphate delta isomerase, Malaria, Mevalonate pathway, Non-mevalonate pathway, Plant, Plastid, Protozoa, Squalene, Terpene, Terpenoid, (E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate, 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase.


Acetyl-CoA (acetyl coenzyme A) is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism.

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The Apicomplexa (also called Apicomplexia) are a large phylum of parasitic alveolates.

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Bacteria (common noun bacteria, singular bacterium) is a type of biological cell.

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Dimethylallyl pyrophosphate

Dimethylallyl pyrophosphate (DMAPP; or alternatively, dimethylallyl diphosphate (DMADP); also isoprenyl pyrophosphate) is an isoprenoid precursor.

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Dimethylallyltranstransferase (DMATT), also known as farnesylpyrophosphate synthase (FPPS) or as farnesyldiphosphate synthase (FDPS), is an enzyme that catalyzes the transformation of dimethylallylpyrophosphate (DMAPP) and isopentenyl pyrophosphate (IPP) into farnesylpyrophosphate (FPP).

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Geranyl pyrophosphate

Geranyl pyrophosphate (GPP), also known as geranyl diphosphate (GDP), is an intermediate in the HMG-CoA reductase pathway used by organisms in the biosynthesis of farnesyl pyrophosphate, geranylgeranyl pyrophosphate.

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An isomer (from Greek ἰσομερής, isomerès; isos.

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Isopentenyl-diphosphate delta isomerase

Isopentenyl pyrophosphate isomerase (IPP isomerase), also known as Isopentenyl-diphosphate delta isomerase, is an isomerase that catalyzes the conversion of the relatively un-reactive isopentenyl pyrophosphate (IPP) to the more-reactive electrophile dimethylallyl pyrophosphate (DMAPP).

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Malaria is a mosquito-borne infectious disease affecting humans and other animals caused by parasitic protozoans (a group of single-celled microorganisms) belonging to the Plasmodium type.

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Mevalonate pathway

The mevalonate pathway, also known as the isoprenoid pathway or HMG-CoA reductase pathway is an essential metabolic pathway present in eukaryotes, archaea, and some bacteria.

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Non-mevalonate pathway

The non-mevalonate pathway—also appearing as the mevalonate-independent pathway and the 2-C-methyl-D-erythritol 4-phosphate/1-deoxy-D-xylulose 5-phosphate (MEP/DOXP) pathway—is an alternative metabolic pathway for the biosynthesis of the isoprenoid precursors isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP).

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Plants are mainly multicellular, predominantly photosynthetic eukaryotes of the kingdom Plantae.

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The plastid (Greek: πλαστός; plastós: formed, molded – plural plastids) is a double-membrane organelle found in the cells of plants, algae, and some other eukaryotic organisms.

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Protozoa (also protozoan, plural protozoans) is an informal term for single-celled eukaryotes, either free-living or parasitic, which feed on organic matter such as other microorganisms or organic tissues and debris.

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Squalene is a natural 30-carbon organic compound originally obtained for commercial purposes primarily from shark liver oil (hence its name, as Squalus is a genus of sharks), although plant sources (primarily vegetable oils) are now used as well, including amaranth seed, rice bran, wheat germ, and olives.

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Terpenes are a large and diverse class of organic compounds, produced by a variety of plants, particularly conifers, and by some insects.

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The terpenoids, sometimes called isoprenoids, are a large and diverse class of naturally occurring organic chemicals derived from terpenes.

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(E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate

(E)-4-Hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP or HMB-PP) is an intermediate of the MEP pathway (non-mevalonate pathway) of isoprenoid biosynthesis.

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4-Hydroxy-3-methylbut-2-enyl diphosphate reductase

4-Hydroxy-3-methylbut-2-enyl diphosphate reductase (isopentenyl-diphosphate:NADP+ oxidoreductase, LytB, (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase, HMBPP reductase, IspH, LytB/IspH) is an enzyme in the non-mevalonate pathway.

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3-isopentenyl pyrophosphate, Isopentenyl diphosphate.


[1] https://en.wikipedia.org/wiki/Isopentenyl_pyrophosphate

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