Table of Contents
33 relations: Allopregnanolone, Allosteric modulator, Anesthesia, Barbiturate, Benzodiazepine, Biological half-life, Biosynthesis, Clinical trial, Endogeny (biology), Enzyme, Epimer, Epipregnanolone, GABAA receptor, Hormone, Learning disability, Menstrual cycle, Natural product, Neurosteroid, Pregnancy, Pregnanolone, Premenstrual dysphoric disorder, Progesterone, Protein subunit, Reaction intermediate, Receptor antagonist, Saccade, Sedation, 3α-Hydroxysteroid dehydrogenase, 3β-Androstanediol, 3β-Dihydroprogesterone, 3β-Hydroxysteroid dehydrogenase, 5α-Dihydroprogesterone, 5α-Reductase.
Allopregnanolone
Allopregnanolone is a naturally occurring neurosteroid which is made in the body from the hormone progesterone. Isopregnanolone and Allopregnanolone are neurosteroids and Pregnanes.
See Isopregnanolone and Allopregnanolone
Allosteric modulator
In pharmacology and biochemistry, allosteric modulators are a group of substances that bind to a receptor to change that receptor's response to stimuli.
See Isopregnanolone and Allosteric modulator
Anesthesia
Anesthesia or anaesthesia is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes.
See Isopregnanolone and Anesthesia
Barbiturate
Barbiturates are a class of depressant drugs that are chemically derived from barbituric acid.
See Isopregnanolone and Barbiturate
Benzodiazepine
Benzodiazepines (BZD, BDZ, BZs), colloquially called "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.
See Isopregnanolone and Benzodiazepine
Biological half-life
Biological half-life (elimination half-life, pharmacological half-life) is the time taken for concentration of a biological substance (such as a medication) to decrease from its maximum concentration (Cmax) to half of Cmax in the blood plasma.
See Isopregnanolone and Biological half-life
Biosynthesis
Biosynthesis, i.e., chemical synthesis occuring in biological contexts, is a term most often referring to multi-step, enzyme-catalyzed processes where chemical substances absorbed as nutrients (or previously converted through biosynthesis) serve as enzyme substrates, with conversion by the living organism either into simpler or more complex products.
See Isopregnanolone and Biosynthesis
Clinical trial
Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison.
See Isopregnanolone and Clinical trial
Endogeny (biology)
Endogenous substances and processes are those that originate from within a living system such as an organism, tissue, or cell.
See Isopregnanolone and Endogeny (biology)
Enzyme
Enzymes are proteins that act as biological catalysts by accelerating chemical reactions.
See Isopregnanolone and Enzyme
Epimer
In stereochemistry, an epimer is one of a pair of diastereomers.
See Isopregnanolone and Epimer
Epipregnanolone
Epipregnanolone, also known as 3β-hydroxy-5β-pregnan-20-one, 3β,5β-tetrahydroprogesterone, or 3β,5β-THP, is an endogenous neurosteroid. Isopregnanolone and Epipregnanolone are GABAA receptor negative allosteric modulators, neurosteroids and Pregnanes.
See Isopregnanolone and Epipregnanolone
GABAA receptor
The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.
See Isopregnanolone and GABAA receptor
Hormone
A hormone (from the Greek participle ὁρμῶν, "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physiology and behavior.
See Isopregnanolone and Hormone
Learning disability
Learning disability, learning disorder, or learning difficulty (British English) is a condition in the brain that causes difficulties comprehending or processing information and can be caused by several different factors.
See Isopregnanolone and Learning disability
Menstrual cycle
The menstrual cycle is a series of natural changes in hormone production and the structures of the uterus and ovaries of the female reproductive system that makes pregnancy possible.
See Isopregnanolone and Menstrual cycle
Natural product
A natural product is a natural compound or substance produced by a living organism—that is, found in nature.
See Isopregnanolone and Natural product
Neurosteroid
Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors. Isopregnanolone and Neurosteroid are neurosteroids.
See Isopregnanolone and Neurosteroid
Pregnancy
Pregnancy is the time during which one or more offspring develops (gestates) inside a woman's uterus (womb).
See Isopregnanolone and Pregnancy
Pregnanolone
Pregnanolone, also known as eltanolone, is an endogenous inhibitory neurosteroid which is produced in the body from progesterone. Isopregnanolone and Pregnanolone are neurosteroids.
See Isopregnanolone and Pregnanolone
Premenstrual dysphoric disorder
Premenstrual dysphoric disorder (PMDD) is a mood disorder characterized by emotional, cognitive, and physical symptoms.
See Isopregnanolone and Premenstrual dysphoric disorder
Progesterone
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. Isopregnanolone and Progesterone are neurosteroids and Pregnanes.
See Isopregnanolone and Progesterone
Protein subunit
In structural biology, a protein subunit is a polypeptide chain or single protein molecule that assembles (or "coassembles") with others to form a protein complex.
See Isopregnanolone and Protein subunit
Reaction intermediate
In chemistry, a reaction intermediate, or intermediate, is a molecular entity arising within the sequence of a stepwise chemical reaction.
See Isopregnanolone and Reaction intermediate
Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
See Isopregnanolone and Receptor antagonist
Saccade
A saccade (jerk) is a quick, simultaneous movement of both eyes between two or more phases of fixation in the same direction.
See Isopregnanolone and Saccade
Sedation
Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure.
See Isopregnanolone and Sedation
3α-Hydroxysteroid dehydrogenase
3α-Hydroxysteroid dehydrogenase (3α-HSD) is an enzyme (1.1.1.50) that plays a role in the metabolism of steroids and non-steroidal compounds in humans and other species, such as bacteria, fungi, plants, and so on.
See Isopregnanolone and 3α-Hydroxysteroid dehydrogenase
3β-Androstanediol
3β-Androstanediol, also known as 5α-androstane-3β,17β-diol, and sometimes shortened in the literature to 3β-diol, is an endogenous steroid hormone and a metabolite of androgens like dehydroepiandrosterone (DHEA) and dihydrotestosterone (DHT).
See Isopregnanolone and 3β-Androstanediol
3β-Dihydroprogesterone
3β-Dihydroprogesterone (3β-DHP), also known as 3β-hydroxyprogesterone, or pregn-4-en-3β-ol-20-one (4-pregnenolone, δ4-pregnenolone), is an endogenous steroid. Isopregnanolone and 3β-Dihydroprogesterone are Pregnanes.
See Isopregnanolone and 3β-Dihydroprogesterone
3β-Hydroxysteroid dehydrogenase
3β-Hydroxysteroid dehydrogenase/Δ5-4 isomerase (3β-HSD) is an enzyme that catalyzes the biosynthesis of the steroid progesterone from pregnenolone, 17α-hydroxyprogesterone from 17α-hydroxypregnenolone, and androstenedione from dehydroepiandrosterone (DHEA) in the adrenal gland.
See Isopregnanolone and 3β-Hydroxysteroid dehydrogenase
5α-Dihydroprogesterone
5α-Dihydroprogesterone (5α-DHP, allopregnanedione, or 5α-pregnane-3,20-dione) is an endogenous progestogen and neurosteroid that is synthesized from progesterone. Isopregnanolone and 5α-Dihydroprogesterone are neurosteroids and Pregnanes.
See Isopregnanolone and 5α-Dihydroprogesterone
5α-Reductase
5α-Reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism.
See Isopregnanolone and 5α-Reductase
References
Also known as 3β,5α-Tetrahydroprogesterone, 3β-Hydoxy-5α-pregnan-20-one, Epiallopregnanolone, Isoallopregnanolone, Sepranolone.